Biotechnology Sector Trends Higher with Breakthrough Clinical Trials, Collaborations & License Agreements
CORAL SPRINGS, Florida, July 16, 2014 /PRNewswire/ --
Biotechnology Companies strive to improve cancer treatment and develop innovative therapies as biotech sector sees growth as well as registered success: GenSpera, Inc. (OTC: GNSZ), Codexis, Inc. (NASDAQ: CDXS), Eli Lilly and Company (NYSE: LLY), Pfizer Inc. (NYSE: PFE), Johnson & Johnson (NYSE: JNJ) and Seattle Genetics (NASDAQ: SGEN).
GenSpera, Inc. (OTCQB: GNSZ), a leader in developing prodrug therapeutics for the treatment of cancer, releases the APPLE 2014 presentation. Devalingam Mahalingam, MD, PhD, Principal Investigator of the G-202 Phase II trial in hepatocellular carcinoma (HCC) patients, presented the HCC clinical trial update for G-202 at the 5th Asia-Pacific Primary Liver Cancer Expert Meeting Saturday, July 12th, in Taipei, Taiwan.
Dr. Mahalingam, an oncologist at the Cancer Therapy & Research Center at the University of Texas Health Science Center at San Antonio, presented interim results from the Phase Ib and ongoing Phase II study in hepatocellular carcinoma (HCC) patients who had previously progressed on, or who were intolerant of, sorafenib. Historically, this patient population has a median time to progression of only two months when they enter subsequent clinical trials. Impressively, 80% of patients treated with G-202 had stable disease (no tumor growth) at two months and 50% of patients exhibited stable disease at 4 months on study.
Read this FULL GNSZ press release at http://www.fnmprofiles.com/profiles-gnsz.html
"The efficacy and safety analyses on patients enrolled to date on this study continue to demonstrate that G-202 holds promise for patients with advanced HCC, with half the patients showing disease stability at 4 months and the majority of patients tolerating G-202 with minimal toxicities," stated Dr. Mahalingam.
GenSpera also recently announced that Kareg Corporation's Director of Research, Sheldon S. Traube, has issued the following research report on the company.
GNSZ is attractive for speculative accounts seeking above-average appreciation potential based upon the considerations listing in the full report. Based on the company's attractive growth prospects with a pipeline of products based upon its unique platform targeting large tumor applications; and strong development and experienced management team that has taken drugs successfully through clinical trials, we recommend the purchase of GNSZ stock for speculative accounts seeking long-term capital appreciation. Kareg's target more than a double within the next 12-24 months. Read the full report: http://www.genspera.com/press/140711_Genspera_research_report_July2014.pdf
Codexis, Inc. (NASDAQ: CDXS), a leading developer of biocatalysts for the pharmaceutical and fine chemical industries, today announced the signing of a platform technology license agreement with GlaxoSmithKline (GSK). Under the terms of the agreement, Codexis granted GSK a license to use Codexis' proprietary CodeEvolver(R) protein engineering platform technology in the field of human healthcare. The license allows GSK to use Codexis' platform technology to develop novel enzymes for use in the manufacture of GSK's pharmaceutical and health care products. GSK may also use the licensed technology to develop new therapeutic, diagnostic and prophylactic products in the human health field. Upon completion of technology transfer, GSK will have Codexis' state-of-the-art CodeEvolver protein engineering platform installed at its Upper Merion, Pennsylvania research and development site.
Eli Lilly and Company (NYSE: LLY) has rebooted the Lilly for Better Health™ program, with several innovative enhancements to lillyforbetterhealth.com that help enrich the user experience with Lilly's non-product-branded health education. Changes to the site include improved ease of use, interactive engagement and an updated mobile experience. Lilly for Better Health is one of the many ways Lilly goes beyond medicine to support individuals and caregivers on their health care journeys. The program, and its website, lillyforbetterhealth.com, recognized by the MarCom Awards, Aster Awards and eHealthcare for excellence in health communication, offer nearly 100 non-product-branded health education resources in English and Spanish, plus information on health-related topics, such as diabetes, depression, exercise and stress.
Pfizer Inc. (NYSE: PFE) recently announced the opening of a new 280,000 square-foot Research and Development (R&D) hub in Cambridge, Mass. The new Pfizer facilities in Kendall Square bring together 1,000 colleagues from three area locations and position Pfizer in closer proximity to leading academic institutions, hospitals and patient organizations. "Our new Kendall Square presence in Cambridge represents an important milestone in Pfizer's approach to creating a sustainable R&D engine that is designed to yield a flow of innovative therapies year after year," said Mikael Dolsten, M.D., Ph.D., President of Worldwide Research and Development at Pfizer. "Having all of our Cambridge-area researchers working closely together in one of the world's most exciting biomedical ecosystems will allow us to continue our efforts to grow our external collaborations and has the potential to help speed the translation of scientific knowledge into potential medical breakthroughs across areas of unmet need such as lupus, inflammatory bowel disease, kidney disease, type 2 diabetes, muscular dystrophy and Parkinson's disease."
Johnson & Johnson (NYSE: JNJ) recently announced sales of $19.5 billion for the second quarter of 2014, an increase of 9.1% as compared to the second quarter of 2013. Operational results increased 9.4% and the negative impact of currency was 0.3%. Domestic sales increased 14.9%. International sales increased 4.4%, reflecting operational growth of 5.0% and a negative currency impact of 0.6%. Net earnings and diluted earnings per share for the second quarter of 2014 were $4.3 billion and $1.51, respectively. The second-quarter results included a charge for after-tax special items of approximately $0.4 billion, primarily related to an increase in the litigation accrual as well as integration and transaction costs related to the acquisition of Synthes, Inc. Second quarter 2013 net earnings included a charge for after-tax special items of approximately $0.5 billion as shown in the accompanying reconciliation of non-GAAP financial measures. To read the full report, please click here: http://finance.yahoo.com/news/johnson-johnson-reports-2014-second-114500172.html
Seattle Genetics (NASDAQ: SGEN), a biotechnology company, develops and commercializes antibody-based therapies for the treatment of cancer. The company is developing antibody-drug conjugates (ADCs), a technology designed to harness the targeting ability of antibodies to deliver cell-killing agents directly to cancer cells. Its lead product, ADCETRIS (brentuximab vedotin), is an ADC that has been approved in approximately 35 countries, including the United States, Canada, Japan, and members of the European Union for relapsed Hodgkin lymphoma (HL) and relapsed systemic anaplastic large cell lymphoma (sALCL) in collaboration with Takeda Pharmaceutical Company Limited. On Tuesday, SGEN closed down 4.66% on over 1.5 million shares traded.
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