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Clinical Data on Eisai's Oncology Pipeline to be Presented at ASCO Annual Meeting
Diversity of Abstracts Reflects Continued Growth of Eisai's Commitment to
Oncology
WOODCLIFF LAKE, N.J., May 31 /PRNewswire/ -- Eisai announced today that
several abstracts covering clinical data about their oncology pipeline
compounds have been accepted for presentation at the American Society of
Clinical Oncology (ASCO) annual meeting. ASCO takes place in Chicago from
June 1-5, 2007.
These abstracts reveal a growing and diverse oncology clinical
development program at Eisai. In addition to the variety of oncology
product classes under investigation, these compounds are being studied in
advanced diseases where there remains considerable unmet medical need,
particularly in refractory metastatic breast cancer, advanced non-small
cell lung cancer, and advanced ovarian cancer.
The following abstracts highlight data from pipeline compounds that
have been accepted for presentation at this year's ASCO meeting.
Product Abstract Details Location Details
Eribulin Phase II Study of Eribulin Mesylate June 2, 2007 8:00
Mesylate (E7389) Halichondrin B Analog in AM - 1:00 PM
(E7389) Patients with Refractory Breast Cancer Location: S403
Abstract No: Poster Number: 21
1034
Eribulin Phase II Study of Eribulin Mesylate June 2, 2007 8:00
Mesylate (E7389), a Mechanistically Novel AM - 1:00 PM
(E7389) Inhibitor of Microtubule Dynamics, Location: E451a
Abstract No: in Patients with Advanced Non-Small
7546 Cell Lung Cancer (nsclc)
Poster Number: 20
MORAb-003 Novel Phase II Study Design of June 2, 2007
Abstract No: MORAb-003, a Monoclonal Antibody 2:00 PM - 6:00 PM
5583 against Folate Receptor Alpha in Location: S Hall A2
Platinum-Sensitive Ovarian Cancer
in First Relapse
Poster Number: U4
MORAb-003 A Phase I Study of MORAb-003, a Fully June 2, 2007
Abstract No: Humanized Monoclonal Antibody against 2:00 PM - 6:00 PM
5553 Folate Receptor Alpha, in Advanced Location: S Hall A2
Epithelial Ovarian Cancer
Poster Number: R7
E7974 A Phase I Trial of E7974 Administered June 3, 2007
Abstract No: on Days 1 and 15 of a 28-Day Cycle in 8:00 AM - 12:00 PM
2550 Patients With Solid Malignancies Location: S Hall A2
Poster Number: B6
E7974 A Phase I Trial of E7974 Administered June 3, 2007
Abstract No: on Days 1, 8, and 15 of a 28-Day Cycle 8:00 AM - 12:00 PM
2543 in Patients With Solid Malignancies Location: S Hall A2
Poster Number: A13
The expansion of Eisai's oncology discovery, research and clinical
development capabilities complements the company's establishment of its
oncology sales and marketing operations in the United States. Through its
acquisition in 2006 of four marketed oncology products, Eisai also obtained
key oncology personnel and expertise, including a sales force. Most
recently, Eisai acquired Morphotek, Inc., which discovers and develops
therapeutic monoclonal antibodies through its proprietary technologies.
Morphotek has preclinical and clinical development programs underway in
several therapeutic categories, including oncology. Both acquisitions
expand Eisai's capabilities into the biologic therapeutics field.
Eisai is committed to building its commercial oncology infrastructure
and is well positioned to market new oncology products that originate from
its research and discovery efforts or through future acquisition,
co-promotion or in-licensing opportunities. That growth will help Eisai
address the unmet medical needs of patients, especially cancer patients,
throughout the world.
About Eisai Inc.
Eisai Inc. is a U.S. pharmaceutical subsidiary of Eisai Co., Ltd., a
research-based human health care (hhc) company that discovers, develops and
markets products throughout the world. Eisai focuses its efforts in three
therapeutic areas: neurology, gastrointestinal disorders and
oncology/critical care. Established in 1995 and ranked among the top-20
U.S. pharmaceutical companies (based on retail sales), Eisai Inc. began
marketing its first product in the United States in 1997 and has rapidly
grown to become an integrated pharmaceutical business with sales of
approximately $2.6 billion in fiscal year 2006 (year ended March 31, 2007).
Eisai Inc. employs approximately 1,500 people at its headquarters in
Woodcliff Lake, NJ, at its state-of-the-art pharmaceutical production and
formulation research and development facility in Research Triangle Park,
NC, and in the field. For more information about Eisai, please visit
http://www.eisai.com.
About Eisai Medical Research Inc.
Eisai Medical Research Inc., a U.S. pharmaceutical subsidiary of Eisai
Co., Ltd., headquartered in Ridgefield Park, NJ, is focused on clinical
drug development of new chemical entities and of new indications for
marketed products.
About Morphotek, Inc.
Morphotek(R), Inc., a U.S. subsidiary of Eisai Co., Ltd., was acquired
by Eisai in April 2007. Founded in 2000 and located in Exton, PA, Morphotek
is a biopharmaceutical company which discovers and develops monoclonal
antibodies through the use of proprietary human antibody technology called
Human MORPHODOMA(R). Morphotek has assembled a strong pipeline of lead
products in the areas of oncology and inflammation and infectious diseases.
It has programs in clinical development and in preclinical stage moving
towards IND filing. For further information, visit
http://www.morphotek.com.
About Eisai Co., Ltd.
Eisai Co., Ltd. is a research-based human health care company that
discovers, develops and markets products throughout the world. Through a
global network of research facilities, manufacturing sites and marketing
subsidiaries, Eisai actively participates in all aspects of the worldwide
health care system. Eisai employs more than 9,000 people worldwide.
SOURCE Eisai
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