Do-Coop Technologies Introduces Neowater(TM) - Solubilization Enhancer to its Expanding Product Portfolio

New Breakthrough Product Enhances Solubilization of Insoluble, Hydrophobic

Molecules and Compounds

Apr 06, 2006, 01:00 ET from Do-Coop Technologies Ltd.

    OR-YEHUDA, Israel, April 6 /PRNewswire/ -- Do-Coop Technologies Ltd., a
 privately held corporation based in Israel, announced today the commercial
 availability of Neowater(TM) - Solubilization Enhancer, a new product that
 enables or increases the solubility of hydrophobic, insoluble molecules and
 drugs. As with the entire Neowater-based product line, the Solubilzation
 Enhancer product is also generic, simple to use, and can be easily
 incorporated into any type of compounds with dramatic results.
     About Neowater
     Neowater is an enabling technology that is based on breakthrough
 water-based nanotechnology. Unlike traditional, dry nanotechnology, which
 focuses on a nanoparticle end product, Neowater builds upon the unique
 properties of nanoparticles to modify the physical properties of water
 molecules around them.
     Each nanoparticle within Neowater, with its huge surface, creates an
 effect known as the "surface effect," and in turn organizes the water
 molecules surrounding it. This is similar to the surface effect of
 organelles within living cells. Both the organelles and the nanoparticles
 use this unique mechanism to create intracellular water. While the former
 is within cells and organs and cannot be harnessed nor used in a lab bench,
 the latter one, which is branded as Neowater, can.
     This technology, developed in Israel, produces water whose physical
 properties mimic that of intracellular water using inorganic, insoluble
 crystals introduced in water in a patented process. Neowater, with its
 stable system of largely hydrated nano-particles, like non-ionic detergent
 derived micelles, reduces the entropy of aqueous solutions. In addition, by
 design, it exhibits both hydrophilic and hydrophobic properties.
     Neowater-based products significantly accelerate and improve the
 efficiency of biological reactions.
     About Neowater(TM) - Solubilization Enhancer
     "Biotech and Pharma companies have in their portfolios a significant
 amount of compounds and drugs which have been proven effective in vitro,
 yet they are very insoluble and thus unusable, such as novel cancer
 therapeutic drugs. Neowater technology dramatically enhances the solubility
 of those compounds that are difficult-to-solvate, or that are used with
 common solvents but exhibit poor pharmacokinetics. Using our new product,
 Biotech and Pharma companies can solubilize these compounds, enhance both
 their stability and bio-availability, and thus can extend and protect their
 intellectual property. We have packaged our enabling technology into this
 unique new product that can replace polar solvents such as detergents and
 surfactants, alcohols such as ethanol and other broadly used solvents like
 DMSO. Furthermore, companies can alternatively use this product to reduce
 the solubility of highly soluble, hydrophilic compounds. We anticipate that
 Biotech and Pharma companies will use this product in laboratory tests with
 their own problematic proprietary compounds and drugs, and then return to
 us to license this unique capability from us. As with all of our other
 products, Neowater(TM) - Solubilization Enhancer is very easy to use with
 existing drugs and compounds, and without the need for new equipment or
 processes," said Eran Gabbai, founder, President and CTO of Do-Coop
 Technologies, and the inventor of Neowater technology.
     Do-Coop Technologies is exhibiting (Booth number 2379) at the upcoming
 BIO 2006 conference in Chicago, on April 9-12, 2006, and will also present
 its Neowater technology at the Business Forum on Tuesday, April 11 at
 09:34, room "E".
     Contact information:
     Do-Coop Technologies Ltd.
     Irit Gabbai, +972-3-533-3804

SOURCE Do-Coop Technologies Ltd.