CENTER VALLEY, Pa., April 4, 2008 /PRNewswire/ -- Scientists in fields
as diverse as pharmaceutical research, food science and biology will
benefit from the Olympus FluoroPoint(TM) single molecule fluorescence
detection system for molecular interaction analysis. Already in use in
scores of laboratories around the world, the system, with its high
sensitivity, low sample volumes, flexibility and ease of use, is now
available for the first time to U.S. screening and research laboratories.
FluoroPoint provides scientists with highly accurate and reliable data
for studies involving protein-protein interactions, DNA, RNA, receptor
binding, siRNA, SNP genotyping, enzyme reactions, polymerization,
thermodynamics, and other processes and mechanisms. Useful in a wide
variety of facilities, it provides absolute quantification, rather than the
relative or proportional measurements generated by other techniques. The
system is highly sensitive, yielding accurate results for sample volumes as
small as 30 microliters, thus allowing the conservation of precious
samples. Compatible with 384-well plates and using a plate reader format,
FluoroPoint is easily adopted by pharmaceutical companies for drug
discovery activities, and provides complementary technology to core
facilities and other life science research laboratories.
Biological systems are often more complex and less predictable than the
molecular contexts generally interrogated by biophysicists and chemists.
Whereas typical molecular interaction experiments (using techniques such as
surface plasmon resonance, for instance) use a defined selection of
molecules, FluoroPoint can accurately and specifically perform single
molecule detection in environments that are similar to the physiological
conditions found in living organisms. In contrast to fluorescence plate
readers, which only make aggregate measurements, FluoroPoint delivers true
single molecule data, long trusted by biophysicists.
FluoroPoint offers fluorescence correlation spectroscopy (FCS),
molecular brightness (FIDA), and confocal anisotropy (FIDA-PO)
measurements, all in an automated, user-friendly format. Its
mix-and-measure simplicity means that researchers do not have to do any
washing or other complicated preparatory efforts. Data is available as
quickly as 0.5 seconds per well, depending on the measurements collected.
For more information on the Olympus FluoroPoint molecular interaction
analysis system, contact Olympus America Inc., 3500 Corporate Parkway,
Center Valley PA 18034-0610; phone 1-908-596-0417; visit
www.olympusamerica.com/FluoroPoint or email FluoroPoint@olympus.com.
About Olympus Products for Life Science, Biotechnology and
Olympus America is a recognized leader in applying optical technology
for life science research. With proven expertise in providing advanced
systems to power research, Olympus delivers a portfolio of products for
drug discovery, biotechnology and the life sciences, including microscopes,
endoscopes and surgical instruments, along with diagnostic and scientific
instruments, cameras and software.
Olympus is a precision technology leader, creating innovative
opto-digital solutions in healthcare, life science and consumer electronics
products. Olympus works collaboratively with its customers and its
affiliates worldwide to leverage R&D investment in precision technology and
manufacturing processes across diverse business lines. These include:
-- Gastrointestinal endoscopes, accessories, and minimally invasive
-- Advanced clinical and research microscopes;
-- Lab automation systems, chemistry-immuno and blood bank analyzers and
-- Digital cameras and voice recorders.
Olympus serves healthcare and commercial laboratory markets with
integrated product solutions and financial, educational and consulting
services that help customers to efficiently, reliably and more easily
achieve exceptional results. Olympus develops breakthrough technologies
with revolutionary product design and functionality for the consumer and
professional photography markets, and also is the leader in
gastrointestinal endoscopy and clinical and educational microscopes. For
more information, visit www.olympusamerica.com.