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Quest Group International, Inc. Raises $20 Million, Acquires Extensive New Generation Oncology Portfolio and Announces Three Lead Therapeutic Product Programs
LOS ANGELES, May 18 /PRNewswire-FirstCall/ -- Quest Group
International, Inc. ("Quest") (OTC Bulletin Board: QSTG) today announced
that it entered into a license agreement with Vitae Pharmaceuticals, Inc.,
a privately held company, ("Vitae"), under which it acquired an extensive
portfolio of technology and intellectual property around nuclear receptors
with new generation oncology product candidates for blood and solid tumor
cancers and cancer supportive care. Quest also announced the completion of
a $20 million private placement and detailed its product development
pipeline.
The extensive portfolio of compounds acquired from Vitae includes
selective retinoic acid receptor agonists and antagonists and rexinoids,
the latter being small molecule synthetic compounds. Quest plans to
implement research and development of three lead compounds. Each compound
represents a unique chemical structure, unique class of therapy, and unique
pharmacological function. The first compound will enter phase 2 study for
the treatment of acute leukemia; the second lead compound will be tested
for safety in humans followed by efficacy studies in some of the most
common cancers, including lung and breast cancer. A novel third program is
intended to evaluate and develop a lead compound as therapy to reduce the
toxicity of chemotherapy, in particular, diminish the risk of infection as
consequence of reduction in white blood cell count. In addition to these
three lead compounds Quest has acquired a platform of technology,
intellectual property, and a large library of small molecules, that will be
used for additional discoveries of novel therapeutics.
Dr. Parkash Gill, who will serve as Quest's Chairman of the Scientific
Board, said, "Quest now represents the single largest concentration of
retinoid/rexinoid therapeutics in the world. The company hopes to deliver
on the promise of these therapeutics to drive tumor cells towards
differentiation and/cell death. This approach may also incorporate rational
combination with other therapeutics."
Dr. Harin Padma-Nathan, who will serve as Quest's Chief Executive
Officer, said, "We are pleased to announce the acquisition of an extensive
portfolio of technology and intellectual property around nuclear receptors
with new generation product candidates in clinical testing for both blood
and solid tumor cancers and cancer supportive care. Our experience and
expertise in R&D and drug development in oncology coupled with our long
standing working relationships with the leading cancer centers in the world
brings us added confidence to rapidly advance this novel nuclear receptor
platform. In addition, we have secured strong financial backing from
institutions that will allow us drive our product development pipeline."
$20 Million Private Placement
Quest Group International, Inc. raised $20 million in gross proceeds
from institutional investors in a private placement of common stock. Hunter
World Markets, Inc. of Beverly Hills, California acted as the Company's
sole placement agent. Todd Ficeto, President and Chief Executive Officer of
Hunter World Markets, Inc., said, "I am very pleased to be a part of this
venture and help provide the resources that enable this group of
distinguished scientist with extensive experience in developing some of the
biggest pharmaceutical products of the past decade including Viagra and
Taxol, to acquire and develop exciting new generation oncology products."
Management
Dr. Harin Padma-Nathan will serve as Quest's Chief Executive Officer.
He brings over 20 years of experience in clinical research, drug
development, and regulatory experience. He has been a Professor of Clinical
Urology at the Keck School of Medicine of the University of Southern
California, Medical Director of The Male Clinic, and Chief Scientific
Officer at Insyght Interactive. Dr. Padma-Nathan has also been involved in
numerous clinical research studies and served as the principal investigator
for Viagra and was a lead investigator for other therapies in the field of
erectile dysfunction. Additionally, his clinical research experience
extends to hypertension, BPH, incontinence, coronary artery disease, female
sexual dysfunction, and prostate cancer. He is extensively published,
including in the New England Journal of Medicine.
Dr. Parkash Gill will serve as Quest's Chairman of the Scientific
Board. He is an internationally recognized authority in cancer and vascular
biology, identification and development of therapeutics with application in
cancer, diabetic retinopathy, and macular degeneration. He has played a
pivotal role in the development of three marketed drugs including Taxol(R)
Paxene(R) and DaunoXome(R) and has served on FDA Advisory Committees. He
has been a Professor of Medicine (Hematology, Oncology and Pathology) at
the Keck School of Medicine of the University of Southern California since
July 1999. He has held an endowed chair in Cancer Therapeutic at the same
institution since July 2005. He has authored nearly 200 research
publications in oncology. Dr. Gill has also demonstrated entrepreneur
translation of his research into viable companies, most recently, Vasgene
Therapeutics.
About Hunter World Markets, Inc. (HWM)
Based in Beverly Hills, California, Hunter World Markets, Inc. (HWM) is
a member of NASD and SIPC and offers investment banking, investment
advisory and institutional trading to select clients with a diversity of
sector and industry experience, particularly in North American and European
markets. HWM has equity underwriting capabilities that include capital
rising through initial public offerings and private placements. In
institutional trading, HWM offers highly individualized trading services to
investment advisors, asset managers, pension funds, insurance companies,
hedge funds, banks and other institutional investors, and trades on all
major exchanges in North America and Europe through RBC Dain Rauscher Inc.
About Vitae Pharmaceuticals, Inc.
Vitae Pharmaceuticals is an emerging pharmaceutical company dedicated
to being a leader in rapidly discovering, developing and commercializing
innovative, high value, small molecule medicines, focusing on known
biologic targets with significant unmet medical need. Vitae's two lead
programs are rapidly advancing in the cardiovascular and diabetes
therapeutic areas. Vitae's first and lead program is in renin inhibition
for the treatment of hypertension. Vitae and GlaxoSmithKline formed one of
2005's largest preclinical partnerships to continue to advance Vitae's
renin program.
About Quest Group International, Inc.
Quest Group is an emerging pharmaceutical company with a focus on
nuclear receptor target therapeutics. Quest is pleased to announce the
acquisition of an extensive portfolio of technology and intellectual
property around nuclear receptors with new generation product candidates in
clinical testing for both blood and solid tumor cancers and cancer
supportive care. This extensive portfolio of compounds includes selective
retinoic acid receptor agonists and antagonists and rexinoids, the latter
being small molecule synthetic compounds. Quest plans to implement research
and development of three lead compounds. Each compound represents a unique
chemical structure, unique class of therapy, and unique pharmacological
function. The first compound will enter phase 2 study for the treatment of
acute leukemia, the second lead compound will be tested for safety in
humans followed by efficacy studies in some of the most common cancers,
including lung and breast cancer. A novel third program is intended to
evaluate and develop a lead compound as therapy to reduce the toxicity of
chemotherapy, in particular, to diminish the risk of infection as
consequence of reduction in white blood cell count. In addition to these
three lead compounds, Quest has acquired a platform of technology,
intellectual property, and a large library of small molecules, which will
be used for additional discoveries of novel therapeutics. A group of highly
talented and experienced scientists in this field will lead the Quest
research efforts. The Company has the necessary skills and chemical
resources to produce novel therapies for other human diseases such as bone
repair and healing, cartilage loss, lipid metabolic defects, and diabetes
mellitus.
The Company, from time to time, may discuss forward-looking
information. Except for the historical information contained in this
release, all forward- looking statements are predictions by the Company's
management and are subject to various risks and uncertainties that may
cause results to differ from management's current expectations. Such
factors include the fact that the Company is engaged in early stage
research and does not expect to obtain any revenues for several years and
other risks as detailed from time to time in the Company's registration
statement and reports and filings with the Securities and Exchange
Commission. All forward-looking statements, if any, in this release
represent the Company's judgment as of the date of this release. The
Company disclaims, however, any intent or obligation to update
forward-looking statements.
SOURCE Quest Group International, Inc.
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