Reportlinker Adds Cardiac Rhythm Management (CRM) Devices Report

NEW YORK, Sept. 8 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue.

Cardiac Rhythm Management (CRM) Devices

http://www.reportlinker.com/p0131251/Cardiac-Rhythm-Management-(CRM)-Devices.html

This report analyzes the worldwide markets for Cardiac Rhythm Management (CRM) Devices in Millions of US$ by the following segments: Implantable Cardioverter Defibrillators (ICD), Pacemakers, External Defibrillators, and EP Catheterization, Mapping, and Ablation (CMA) devices. The report provides separate comprehensive analytics for the United States, and Rest of World. Annual forecasts are provided for each region for the period 2006 through 2015. A six-year historic analysis is also provided for these markets. The report profiles 59 companies including many key and niche players worldwide such as Bard Electrophysiology, Biosense Webster, Inc., Boston Scientific Corporation, Biotronik GMBH & Co. KG, Medtronic, Inc., Medtronic CryoCath LP, Vitatron Nederland BV, Philips Healthcare, St. Jude Medical, Inc., and Sorin Group. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.

I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

Study Reliability and Reporting Limitations I-1

Disclaimers I-2

Data Interpretation & Reporting Level I-3

Quantitative Techniques & Analytics I-3

Product Definitions and Scope of Study I-3

Implantable Cardioverter Defibrillators (ICD) I-3

Pacemaker I-4

External Defibrillators I-4

Electrophysiology (EP) Catheterization, Mapping, and Ablation (CMA) I-4

II. EXECUTIVE SUMMARY

1. INDUSTRY OVERVIEW II-1

A Prelude II-1

Market Structure II-1

Table 1: World Market for Cardiac Rhythm Management Devices (2008 & 2010P): Percentage Market Share Breakdown of Leading Players - Medtronic, St. Jude Medical, Boston Scientific (Guidant), and Others (includes corresponding Graph/Chart) II-2

Table 2: World Market for High Power CRM Devices (2008 & 2010P): Percentage Market Share Breakdown of Leading Players Medtronic, St. Jude Medical, Boston Scientific (Guidant), and Others (includes corresponding Graph/Chart) II-2

Table 3: World Market for Low Power CRM Devices (2008 & 2010P): Percentage Market Share Breakdown of Leading Players - Medtronic, St. Jude Medical, Boston Scientific (Guidant), and Others (includes corresponding Graph/Chart) II-3

Table 4: World Market for Implantable Cardioverter

Defibrillator (ICD) (2008 & 2010P): Percentage Market Share Breakdown of Leading Players - Medtronic, Boston Scientific (Guidant), St. Jude Medical, and Others (includes corresponding Graph/Chart) II-3

Table 5: World Catheter Ablation Devices Market (2007): Percentage Market Share Breakdown of Leading Players - Johnson & Johnson, St.Jude Medical, Boston Scientific, Bard, Medtronic, CryoCath, and Others (includes corresponding Graph/Chart) II-4

Table 6: World External Defibrillators Market (2006): Percentage Market Share Breakdown of Leading Players - Medtronic, Philips and Others (includes corresponding Graph/Chart) II-4

Table 7: World Market for Advanced Cardiac Resynchronization Therapy (CRT) Devices (2005): Percentage Market Share Breakdown of Leading Players - Medtronic, Boston Scientific (Guidant), St. Jude Medical, and Others (includes corresponding Graph/Chart) II-4

Noteworthy Trends & Issues II-5

Infamous Product Recalls Throw Growth Off-track II-5

Market Shapes Up After the Recall Shock II-5

Regulatory Riders Knit to Ensure Greater Device Reliability II-6

Growing Proportion of Obese Population: A Major Demographic Driver II-6

Replacements to Drive the Growth of ICDs II-6

Developments in Energy-Based Therapies Augur Well for Cardiac Ablation Treatments II-6

Expanding Applications Lend Traction to Growth II-7

Prices of Cardiac Pacemakers Soften II-7

Heart Patients Using ICD, Enjoy Satisfactory Quality Life II-8

Pacemakers Ensure Effective Management of Non-Systolic Heart Failures II-8

CRT: An Effective Treatment for Bradycardia, Tachycardia & Fibrillation II-8

ICDs in Pediatric Care Shows Promise II-9

Emerging Therapies for the Treatment of Atrial Fibrillation II-9

New Generation CRM Devices Feature Superior Benefits II-10

MRI-Compatible Pacemakers & ICDs II-10

Resistance Against Electronic Interferences II-10

Confusion Over the Use of CRM Devices Threaten Perceived Effectiveness II-11

Breathing Disorders in Patients Implanted with Pacemakers: A Cause for Concern II-12

Approval of Untested Pacemaker Connectors Raises Eyebrows II-12

ICD Lead Failure Demands Immediate Attention II-13

Pacemaker Hacking Has the Industry Up by Its Ears II-13

Pacemakers Face Stiff Competition from CRT-D Devices II-14

ICDs More Prone to Malfunction than Pacemakers II-14

Conclusion II-14

Technology Innovation: A Futuristic Rumination II-15

The Heart to Power CRM Devices: The Future of CRM Therapies II-15

Genetic Advances to Yield Replacement for Pacemakers II-15

Ablation Technology Undergoing Innovations II-15

Vein Ablation Catheter Proves Successful in Cases of Paroxysmal Atrial Fibrillation II-16

Ablation Therapy Useful in Treating Persistent/ Permanent Atrial Fibrillation (PPAF) II-16

Magnetic Navigation: An Innovation in Catheter Ablation II-16

New Force-Sensing Ablation Catheter Aims to Aid Physician Decision Making II-17

Pricing & Reimbursements: Critical Determinants of Growth II-17

New Guidelines Issued for Safe Management of CRM Devices in the US and Europe II-18

2. REGIONAL MARKET OVERVIEW II-19

2a. THE UNITED STATES II-19

A.Market Analysis II-19

Outlook II-19

Market Overview II-19

Demand for Automated External Defibrillators Shoots Up in the US II-19

Market Share Statistics II-20

Table 8: US Market for Implantable Cardioverter Defibrillator (ICD) (2007& 2010): Percentage Breakdown of Player Market Shares - Medtronic, Boston Scientific (Guidant), St Jude Medical, and Others (includes corresponding Graph/Chart) II-20

Table 9: US Market for Core Pacemakers & CRT-P (2007 & 2010): Percentage Breakdown of Player Market Shares - Medtronic, St. Jude, Boston Scientific, and Others (includes corresponding Graph/Chart) II-21

Cardiovascular Disease Incidence Statistics II-21

Table 10: Total Direct Economic Cost of Cardiovascular Diseases (CVDs) in the United States (2009E): Breakdown by Disease Type (In US$ Billion) (includes corresponding Graph/Chart) II-21

Table 11: Total Direct Economic Cost of Cardiovascular Diseases (CVDs) in the United States (2009E): Percentage Breakdown by Type of Expenditure (includes corresponding Graph/Chart) II-22

Table 12: Prevalence of Cardiovascular Diseases in Adults Over the Age of 20 Years in the United States (2006): Percentage Breakdown by Age and Gender (includes corresponding Graph/Chart) II-22

Table 13: Cardiovascular Diseases in the United States (2006): Percentage Breakdown of Deaths Caused by Cardiovascular Diseases by Type (includes corresponding Graph/Chart) II-23

B.Market Analytics II-23

Table 14: US Recent Past, Current & Future Analysis for Cardiac Rhythm Management Devices by Product Segment - Implantable Cardioverter Defibrillators, Pacemakers, External Defibrillators, and EP Catheterization, Mapping, and Ablation (CMA) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2006 through 2015 (includes corresponding Graph/Chart) II-23

Table 15: US Historic Review for Cardiac Rhythm Management Devices by Product Segment - Implantable Cardioverter Defibrillators, Pacemakers, External Defibrillators, and EP Catheterization, Mapping, and Ablation (CMA) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2005 (includes corresponding Graph/Chart) II-24

Table 16: US 10-Year Perspective for Cardiac Rhythm Management Devices by Product Segment - Percentage Breakdown of Dollar Sales for Implantable Cardioverter Defibrillators, Pacemakers, External Defibrillators, and EP Catheterization, Mapping, and Ablation (CMA) for Years 2006, 2009 & 2015 (includes corresponding Graph/Chart) II-24

2b. REST OF WORLD II-25

A.Market Analysis II-25

Outlook II-25

Market Share Statistics II-25

Table 17: Implantable Cardioverter Defibrillator (ICD) Market in EMEA, Asia, & South America (2007&2010): Percentage Market Share Breakdown of Leading Players - Medtronic, Boston Scientific (Guidant), St Jude Medical, and Others (includes corresponding Graph/Chart) II-25

Table 18: Core Pacemakers & CRT-P Market in EMEA, Asia, & South America (2007&2010): Percentage Market Share Breakdown of Leading Players - Medtronic, St. Jude, Boston Scientific and Others (includes corresponding Graph/Chart) II-26

Focus on Select Markets II-26

Europe II-26

Highly Competitive External Defibrillators Market Paves Way for Consolidations II-27

UK II-27

Asia-Pacific II-28

China II-28

B.Market AnalyticsII-29

Table 19: Rest of World Recent Past, Current & Future Analysis for Cardiac Rhythm Management Devices by Product Segment - Implantable Cardioverter Defibrillators, Pacemakers, External Defibrillators, and EP Catheterization, Mapping, and Ablation (CMA) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2006 through 2015 (includes corresponding Graph/Chart) II-29

Table 20: Rest of World Historic Review for Cardiac Rhythm Management Devices by Product Segment - Implantable Cardioverter Defibrillators, Pacemakers, External Defibrillators, and EP Catheterization, Mapping, and Ablation (CMA) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2005 (includes corresponding Graph/Chart) II-30

Table 21: Rest of World 10-Year Perspective for Cardiac Rhythm Management Devices by Product Segment - Percentage Breakdown of Dollar Sales for Implantable Cardioverter Defibrillators, Pacemakers, External Defibrillators, and EP Catheterization, Mapping, and Ablation (CMA) for Years 2006, 2009 & 2015 (includes corresponding Graph/Chart) II-30

3. PRODUCT OVERVIEW II-31

Sudden Cardiac Arrest: A Leading Cause of Death II-31

Cardiac Rhythm Management (CRM): A Definition II-31

Implantable Cardioverter Defibrillators (ICDs) II-31

Surgical Implantation of ICDs: The Procedure II-32

ICDs - The Benefits II-32

Types of ICDs II-33

ICDs: An Evolution Scan II-33

Complications Associated With ICD Usage II-33

CRT-D - A New Therapeutic Device II-33

Pacemakers II-34

Surgical Implantation of Pacemakers: The Procedure II-34

Types of Pacemakers II-34

Methods of Pacing II-35

Fixed Rate Pacemakers II-35

Demand Pacemakers II-35

Rate-Responsive Pacemaker II-35

Pacemakers: An Evolution Scan II-36

Complications Associated with Pacemakers II-36

Advent of CRT-P II-36

Electrophysiology (EP) Catheterization, Mapping, and Ablation (CMA) II-36

The Ablation Procedure II-37

External Defibrillators II-37

Types of AEDs II-38

Cardiac Rhythm Disorders: A Brief Review II-38

Cardiac Arrhythmias II-39

Classification of Cardiac Arrhythmias II-39

Bradycardia II-39

Tachycardia II-40

Atrial Fibrillation II-40

Heart Blocks II-41

Syncope II-41

Sick Sinus Syndrome II-41

Cardiomyopathy II-42

4. PRODUCT APPROVALS/INTRODUCTIONS II-43

Biosense Catheter Receives FDA Marketing Approval II-43

St. Jude Medical Secures Approval for Atlas II ICD from Japan II-43

Zoll Medical Defibrillators Receive FDA Clearance II-43

St. Jude Medical Receives CE Mark for Integrated Irrigation Pump and Ablation Generator II-43

AtriCure Secures FDA 510(k) Approval for Coolrail Device II-44

Hansen Medical Gains FDA Approval for CoHesion(TM) Module II-44

St. Jude Medical Obtains CE Mark and FDA Approval for HIFU Surgical Ablation Solutions II-45

Biosense Releases NAVISTAR(R) RMT THERMOCOOL(R) Catheter II-45

Atricure Unveils The ORLab(TM) II-45

Cardima Receives SFDA Approval to Market INTELLITEMP(R) in China II-46

ZOLL Obtains 510K Clearance to Sell and Market Zoll R Series Code-Ready Defibrillator II-46

ST. Jude Medical Obtains FDA and CE Mark Approval for New Epicor LP Cardiac Ablation System II-47

Cardima Obtains Approval for Marketing Surgical Ablation System in Thailand II-47

ATS Medical Introduces First CryoMaze Surgical Ablation Clamp II-47

CardioNet Unveils New Reporting Package for Atrial Fibrillation Treatment II-47

Boston Scientific Defibrillator Receives CE Mark Approval II-48

TyRx Introduces New Anti-bacterial Envelope, AIGISRX(TM) ICD II-48

St. Jude Medical Receives Approval from Japanese MHLW II-49

Boston Scientific Secures FDA Approval for CRM Solutions II-49

Sorin Group Develops New-Generation CRT-D Implants II-49

BSC Secures CE Mark Approval for ALTRUA Pacemakers II-49

Medtronic Secures FDA Approval for New Vision 3D Devices II-50

Medtronic Obtains FDA Approval for Software Update II-51

St. Jude Medical Obtains FDA Approval for SJM Cardiac Monitor II-51

Boston Scientific Obtains Approval For Cognis CRT-D And Teligen ICD II-51

FDA Approves Medtronic's Medtronic Sprint Quattro Secure(R) S Lead II-51

Medtronic Obtains CE Mark Approval for Pacemaker and Pacing Leads II-52

St. Jude Medical Obtains Japanese Approval for Victory(R) Pacemakers Family II-52

Sorin Group Obtains Approval For Isoline Defibrillation Leads In Japan II-52

BSC Secures FDA Approval for New ALTRUA Pacemakers II-53

St. Jude Medical Obtains Approval for Durata Defibrillation Lead II-53

St. Jude Medical Obtains Japanese Approval for Durata Defibrillation Lead II-54

St. Jude Medical Obtains Japanese Approval for Victory Family of Pacemakers II-54

Sorin Group Gains FDA Approval for OVATIO(TM) II-54

Sorin SpA Gains FDA Approval for REPLY II-54

Medtronic Receives Approval for Lead Integrity Alert(TM) II-55

Physio-Control Gains FDA Approval for LIFEPAK(R) 20e Defibrillator/Monitor II-55

TyRx Introduces New Anti-Bacterial Envelope, AIGISRX(TM) ICD II-55

LifeWatch Introduces Next-Generation Monitor, LifeStar ACT III Platinum II-56

eCardio Launches eVolution, New Cardiac Monitoring System II-56

Philips Introduces PageWriter TC70 Cardiograph II-56

Sorin Group Announces Commercial Release and First Implant of PARADYM(TM) CRT 8750 II-57

St. Jude Medical Introduces QuickOpt(R) Timing Cycle Optimization in CRT-D II-57

Cardiac Science Unveils Simple Electronic Reporting System II-57

Mennen Medical Introduces VitaLogik(R) 4000 Line II-58

BIOTRONIK Releases CRT-P in US Market II-58

Vermed Releases Defibrillation Pads Series and Universal Connector System II-59

St. Jude Releases Reflexion Spiral X(TM) in US II-59

St. Jude Introduces Therapy Cool Path II-60

Ablation Frontiers Obtains CE Marks and Commercially Launches Cardiac Ablation System II-60

Isolator(R) Bipolar Ablation Clamp System of AtriCure Obtains FDA 510(k) Clearance II-60

Hansen Medical Receives CE Mark Approval for Sensei Robotic Catheter System and Artisan Control Catheter II-61

ZOLL AED Pro Secures FDA Approval for Use with See-Thru CPR(TM)

Technology II-61

European Approval for CardioFocus's Endoscopic Ablation System II-61

Leipzig's Heart Centre Unveils New Catheter Ablation Solution II-62

CardioFocus Receives CE Mark for Endoscopic Ablation System II-62

FDA Approves SOLAR(TM) Surgical Ablation System of MedicalCV II-63

Cardima Launches Cardima Surgical Ablation Probe with 24 Electrodes II-63

Stereotaxis Receives Approval from FDA for a 8mm Ablation Catheter II-63

Japan Approves Sprint Quattro(TM) of Medtronic II-63

Boston Scientific Receives European Clearance for CONFIENT(TM) ICD II-64

St. Jude Receives Japanese Approval for CRT-D Systems II-64

St. Jude Receives CE Mark and FDA Approval for QuickOpt(TM) II-65

Hansen Medical Unveils Sensei(TM) Robotic Catheter System II-65

St. Jude Medical Receives FDA Approval for Two Devices II-65

St. Jude Medical Obtains European CE Mark Clearance for Cardiac Devices II-66

St. Jude Medical Receives Approval for Pacemaker in the US and UK II-66

Boston Scientific Receives FDA Approval for ACUITY(R) Steerable Lead II-67

St. Jude Medical Receives FDA Approval for its New CRM Device II-67

The Sorin Group Receives CE Mark for Its New Reply(TM) Pacemakers II-67

St. Jude Medical Receives FDA Approval for Merlin.net Patient Care Network II-68

Europe Approves Implantable Cardiac Rhythm Appliance of Boston Scientific II-68

CE Mark and FDA Approve Zephyr(TM) Pacemaker of St. Jude II-68

FDA Gives Clearance for Atlas II+ HF CRT-D of St. Jude II-69

St Jude Medical Receives Approval from Japan II-69

Sorin Launches REPLY Following CE Mark Certification II-69

BIOTRONIK Launches Lumax 340 VR-T XL ICD II-70

Medtronic to Launch Medtronic CareLink Network in EU II-70

St. Jude Medical Receives Approval for Using CRT-D Systems in Japan II-70

St. Jude Medical Receives FDA Approval for Promote CRT-D and Current ICD II-71

Bio-Detek Receives FDA Approval for PocketCPR(TM) II-71

EZ STEER Bi-Directional Catheter for Treating Abnormal Cardiac Rhythms II-71

Philips Unveils EP Navigator Tool for Complex Cardiac Arrhythmias II-72

Medtronic Launches Advanced Cardiac Defibrillators with Wireless Feature II-72

Sorin Group Introduces OVATIO Implantable Cardioverter Defibrillators II-73

5. RECENT INDUSTRY ACTIVITY II-74

Medtronic Takes Over Ablation Frontiers II-74

Philips Signs a Deal with Bard Electrophysiology II-74

Boston Scientific Bags CRM Contract from Dept. Of Veterans Affairs II-74

Medtronic and Boston Scientific Inks Agreement to End IP Disputes II-75

St Jude Medical to Invest in Penang II-75

Cardima Enters into a Distribution Agreement with Peerless Medical II-75

Cardiac Science Enters into an Alliance with Boy Scouts of America II-76

Cardima Enters into a New Strategic Surgical Alliance with Biocore II-76

Cardima Enters into a New Strategic Marketing Alliance with On-X Life Technologies II-76

Welch Allyn and ZOLL Medical Corporation Collaborate II-77

Cardima Selects Dot Medical to Distribute Its EP Products in the UK II-77

Royal Philips to Guide 'euHeart' Project II-78

Target Center Acquires HeartSine(R) Defibrillators II-78

St Jude Medical Acquires EP MedSystems II-78

St. Jude Takes Over Radi Medical AB II-78

Medrad to Acquire Possis II-79

Phoenix Acquires Stake in Possis II-79

Biotronik Acquires VascoMed II-79

Medtronic Takes Over CryoCath Technologies II-80

Boston Scientific Takes Over CryoCor II-80

St. Jude Completes Acquisition of MediGuide II-80

Greatbatch Enters Into A Strategic Partnership With Issys II-80

Sorin Group Inks Collaborative Agreement with Greatbatch II-81

Philips Enters into MOU with King's College London on Research Collaboration II-81

Welch Allyn Collaborates with ZOLL Medical Corporation II-81

ZOLL and HealthTrust Sign Purchasing Deal II-82

ZOLL Inks Multi-Year Agreement with Masimo II-82

First Responder Wins Contract from Harvard School of Public Health II-82

Beijing Airport Group to Deploy ZOLL AED Plus Solutions II-83

STH NHS Trust to Deploy New R Series BLS Solutions of ZOLL II-83

Major EMS Centers in China Deploys ZOLL M Series Defibrillator II-83

DRF to Deploy corpuls3 Heart Defibrillators II-84

Riedel & Schulz and GS Elektromed Distributes 8 corpuls3 Medical Units II-84

Trivitron Inks Marketing And Distribution Agreement With Boston Scientific II-84

CardioComm Signs Licensing Agreement with GE Healthcare II-84

Cambridge Heart Licenses Technology for Implantable Devices II-85

Synovis Life Technologies to Divest Interventional Business II-85

Boston Scientific Divests Cardiac Surgery And Vascular Surgery Businesses II-85

Sorin Group Sells Its Vascular Therapy Business to CIDl II-85

Medtronic and Biosense Webster Enter Into Alliance for Advance Cardiac Ablation II-86

ATS Medical Takes Over Surgical Ablation Business of CryoCath II-86

Biosense Webster Enters into a Strategic Alliance with Medtronic II-86

Atricure Takes Over Frigitronics(R) Cryogenic Product Series II-87

Boston Scientific Announces Approval and Launch of VITALITY(TM) DR ICD II-87

Boston Scientific to Reallocate Resources for R&D in CRM II-87

Vicor Technologies Merges with SRKP 6 II-88

Greatbatch Takes Over Biomec II-88

Greatbatch Completes Quan Emerteq Acquisition II-88

Greatbatch Takes Over Enpath Medical II-89

Medtronic to Take Over MRI Safety Patents of Biophan II-89

Teleflex Takes Over Arrow II-89

Edwards Acquires CardioVations Division II-89

Boston Scientific Inks Deal to Take Over Remon Medical Technologies II-90

Sorin and Japan Lifeline Sign Ten-Year CRM Partnership II-90

Royal Philips Joins Hands with Healthcare Entities II-90

Triple Ring Forms Partnership with Aubrey II-90

SurModics and St. Jude Medical Sign Corporate Technology Agreement II-91

Siemens Medical Solutions Extends Strategic Alliance with Biosense Webster II-91

Hansen and St. Jude Enter into Agreements II-91

St. Jude Medical Secures a Cardiac Rhythm Management Devices Contract II-92

Biotronik Secures Cardiac Rhythm Management Contract from Premier II-92

ZOLL Selected to Supply Emergency Preparedness Equipment II-92

Edwards Lifesciences Announces Multi-Year Grant to University of California II-93

St. Jude Medical Announced Plans to Expand Operations in Puerto Rico II-93

Biophan to Make Investment in Myotech II-94

6. FOCUS ON SELECT PLAYERS II-95

Bard Electrophysiology (USA) II-95

Biosense Webster, Inc. (USA) II-95

Boston Scientific Corporation (USA) II-95

Biotronik GMBH & Co. KG (Germany) II-95

Medtronic, Inc. (USA) II-96

Medtronic CryoCath LP (USA) II-96

Vitatron Nederland BV (Netherlands) II-96

Philips Healthcare (The Netherlands) II-97

St. Jude Medical, Inc. (USA) II-97

Sorin Group (Italy) II-97

7. GLOBAL MARKET PERSPECTIVE II-98

Table 22: World Recent Past, Current & Future Analysis for Cardiac Rhythm Management Devices by Geographic Region - United States and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2006 through 2015 (includes corresponding Graph/Chart) II-98

Table 23: World Historic Review for Cardiac Rhythm Management Devices by Geographic Region - United States and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2005 (includes corresponding Graph/Chart) II-99

Table 24: World 10-Year Perspective for Cardiac Rhythm Management Devices by Geographic Region - Percentage Breakdown of Dollar Sales for United States and Rest of World for Years 2006, 2009 & 2015 II-99

Table 25: World Recent Past, Current & Future Analysis for Cardiac Rhythm Management Devices by Product Segment - Implantable Cardioverter Defibrillators, Pacemakers, External Defibrillators, and EP Catheterization, Mapping, and Ablation (CMA) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2006 through 2015 (includes corresponding Graph/Chart) II-100

Table 26: World Historic Review for Cardiac Rhythm Management Devices by Product Segment - Implantable Cardiac Defibrillators, Pacemakers, External Defibrillators, and EP Catheterization, Mapping, and Ablation (CMA) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2005 (includes corresponding Graph/Chart) II-100

Table 27: World 10-Year Perspective for Cardiac Rhythm Management Devices by Product Segment - Percentage Breakdown of Dollar Sales for Implantable Cardioverter Defibrillators, Pacemakers, External Defibrillators, and EP Catheterization, Mapping, and Ablation (CMA) for Years 2006, 2009 & 2015 (includes corresponding Graph/Chart) II-101

III. COMPETITIVE LANDSCAPE

Total Companies Profiled: 59 (including Divisions/Subsidiaries - 146 )

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