NEW YORK, Nov. 25 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

Intranasal Drug Delivery - US Market Trends & Analysis http://www.reportlinker.com/p0164267/Intranasal-Drug-Delivery---US-Market-Trends--Analysis.html

The US intranasal drug delivery market is witnessing an expansion of therapeutic applications from the delivery of conventional local therapeutic drugs to the delivery of systemic therapeutic drugs. The future of the technology hinges onto the effective exploitation of the fact that the nose offers an en-route that bypasses the blood-brain barrier through the olfactory region. The market also stands enthused by the continuous research and development activities, which are gradually opening up opportunities in new therapeutic areas, such as, osteoporosis, pain management, vitamin B12 deficiency, smoking cessation, migraines, nocturnal enuresis, rheumatoid arthritis, sexual dysfunction, cancer therapy, insulin-dependent diabetes, and epilepsy.

These and other market data and trends are presented in "Intranasal Drug Delivery: US Market Trends & Analysis" by BizAcumen, Inc. Our reports are designed to be most comprehensive in geographic coverage and vertical market analyses.

INTRANASAL DRUG DELIVERY BMR-1067

CONTENTS

1. METHODOLOGY 1

Study Reliability and Reporting Limitations 1

Disclaimers 2

Quantitative Techniques & Reporting Level 3

2. GLOBAL MARKET OVERVIEW AND OUTLOOK 3

Drug Delivery: A Quick Primer 3

The Nose: An Attractive Avenue to Cross the Blood Brain Barrier 4

Self-Administration of Drugs Brings Intranasal Drug Delivery Into the Spotlight 5

Research & Technology Opens Up New Therapeutic Areas for Nasal Drug Delivery 5

Recent Product Developments in the US Intranasal Drug Delivery Market (2007) 6

R&D: Critical to the Commercialization of Intranasal Drug Delivery 6

Tight Junction Biology: A Key Speed Breaker in Commercialization 7

RNA Interference (RNAi): A Tool To Manipulate Tight Junctions 7

Why Is Nasal Drug Delivery the Theme of All Drug Delivery Research Projects? 8

Nasal Drug Delivery Devices & Equipments Preservative Free Systems (P.F.S.) 8

Traditional Vs Advanced Intranasal Drug Delivery Devices 10

Pitfalls Of Traditional Delivery Devices 10

The Promise of New Advanced Delivery Devices 10

Bi-Directional Nasal Drug Delivery: A Technology With a Huge Potential 10

Benefits of Bi-Directional Delivery Authenticated Through Research Studies 11

Market for Nasal Spray Devices in the US 12

GSK Wields the Leadership Scepter in the US Intranasal Drugs Market 12

The Batting Order 13

3. MARKET DYNAMICS 13

Innovation in Drug Delivery: A Talisman for Success 13

Controlled Release Technology is the Buzz Word 13

Target-Specific Delivery Devices: Of Critical Value 14

Safety & Cost: Primary Growth Drivers 14

Preservatives Losing Sheen in Nasal Spray Formulations 14

Multi-Dose Containers Evolve to Offer Resistance Against Microbial Contamination 15

Bioavailability: An Important Facet of Intranasal Drug Delivery 15

Chemical Modification 15

Transient Modification & Limited Enzymatic Activity 16

Bioavailability of Large Molecules 16

Bio-Adhesive Polymers: Useful in Increasing Drug Absorption 16

Mixed Opinions on Efficiency of Calcitonin Nasal Spray 16

Nasal Preparations Gaining Foothold in Cough and Allergic Categories 17

Patent Expiries Impact Market Opportunities 17

4. PRODUCT FACTS 19

5. RECENT TECHNOLOGICAL DEVELOPMENTS 20

New-Generation Technologies and Devices 21

ViaNase from Kurve Technology 21

A New Product from OptiNose 21

Nastech's "Tight Junction Biology" Research Program 22

ChiSys(TM) Nasal Delivery Technology from Archimedes 22

6. CORPORATE DEVELOPMENTS 23

Zelos Therapeutics Collaborates with Aegis Therapeutics 23

ImmuneRegen BioSciences Partners with LRRI 23

Avamys(TM) Nasal Spray Receives Approval in Europe 23

PMI-150 Receives Canadian Patent 23

Nastech Enrolls 551 Patients for Phase 2 Trials of PYY3-36

Nasal Spray 24

USFDA Approves FluMist® for Young Children 24

USFDA Approves Veramyst Nasal Spray for Individuals Aged Two Years and Above 24

Kurve Technology Inks Agreement with Schering-Plough 24

MedImmune Clarifies FDA Observations 25

FluMist(R) Receives FDA Approval for Refrigerated Formulation 25

Nastech Regains Rights for PTH1-34 Nasal Spray 25

NASONEX(R) Receives Ease-of-Use Commendation from Arthritis Foundation 25

Aegis Therapeutics Establishes Cedar Therapeutics Inc. 25

EMEA Provides Encouraging Feedback for Avamys(TM) Nasal Spray 25

Kurve Technologies Introduces Blog on Nasal Drug Delivery 26

Archimedes Pharma Commences Phase III Trials for NasalFent® 26

Archimedes Presents New Clinical Data on NasalFent® 26

LigoCyte Commences Clinical Trials for Intranasal Norovirus Vaccine 27

Javelin Pharmaceuticals Reveals Phase 2 Study Results for PMI-100/150 27

Javelin Pharmaceuticals Commences Phase III Studies for PMI-150 27

Nastech Commences Phase 2 Trials for Insulin Nasal Spray 27

ACAAI Reveals Results for Trials of Nasacort® AQ Nasal Spray in Children 28

7. MAJOR PLAYERS 28

Aegis Therapeutics LLC (USA) 28

Alza Corporation (USA) 28

AptarGroup, Inc. (USA) 29

Archimedes Pharma Limited. (UK) 29

AstraZeneca Plc (UK) 29

MedImmune, Inc. (USA) 29

Bayer Consumer Care (USA) 30

Bespak Plc (UK) 30

GlaxoSmithKline Plc (UK) 30

Intranasal Therapeutics, Inc. (USA) 30

Javelin Pharmaceuticals, Inc (USA) 31

Kurve Technology, Inc. (USA) 31

MDRNA, Inc. (USA) 31

Novartis AG (Switzerland) 31

OptiNose AS (Norway) 32

Pfizer, Inc. (USA) 32

Rexam Plc (UK) 32

Schering-Plough Corporation (USA) 32

Sanofi-Aventis S.A. (France) 32

Unigene Laboratories, Inc. (USA) 33

8. MARKET ANALYTICS 33

EXHIBITS

Table 1: The US Nasal Drug Delivery Market: Sales Of Top Six Nasal Formulations for The Year 2005 (In US$ Million)

Table 2: Percentage Market Shares of Leading Intranasal Drug Delivery Players in the US - 2006

Table 3: Percentage Shares of Intranasal Drugs Manufacturer Value in the US - 2012

Table 4: Top 10 Nasal Sprays, Drops and Inhalers Brands Ranked by Dollar Sales Through Drug Stores in the US - 2008 (In US $ Million)

Table 5: Top 10 Nasal Sprays, Drops and Inhalers Brands Ranked by Unit Sales through Drug Stores in the US - 2008 (In Thousand Units)

Table 6: Top Five Nasal Sprays Ranked by Dollar Retail Sales in the US - 2008 (In US $ Million)

Table 7: Projected Revenues for Intranasal Sexual Dysfunction Drugs in the US -2010, 2011 & 2012 (in US$ Million)

Table 8: Intranasal Drug Delivery Market by Therapeutic Area in the US: 2007-2015 (Sales in US$ Million)

Table 9: Percentage Breakdown of Intranasal Drug Delivery Market by Therapeutic Area in the US for the Years 2008 & 2012

COMPANIES PROFILED

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Drug Delivery Technology Industry: Intranasal Drug Delivery - US Market Trends & Analysis

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