TORONTO, Nov. 30 /PRNewswire/ - Sentinelle Medical Inc., a leading manufacturer of MRI coils and advanced visualization software is demonstrating a number of innovative new works-in-progress, including MRI and ultrasound co-registration offering at RSNA 2009.

Aegis(TM) Navigation* performs registration between MRI or CT and live ultrasound images to bring high quality imaging from the scanner room to the ultrasound suite. This permits investigating the same anatomical features under two types of imaging at the same time. Specialized hardware and software automates registration between modalities, and instruments are spatially tracked using advanced 3D optical or magnetic tracking systems. Clinicians select anatomical targets based on information from multiple imaging modalities to maximize sensitivity and specificity, and an interactive targeting interface quickly guides clinicians towards the region of interest. Aegis Navigation can be configured as a standalone system or be customized and integrated directly into ultrasound platforms. The first such product is Aegis Navigation for the Ultrasonix SonixTOUCH ultrasound machine.

"Multi-modality imaging is of utmost importance in the management of liver metastases from colorectal cancer, where every lesion is important." says Dr Laurent Milot of Sunnybrook Health Sciences Centre. "Through our Investigational Studies+, Aegis Navigation has been able to combine Ultrasound and MRI for pre-operative planning of liver resection to provide a 50% increase in the number of lesions detected with Aegis Navigation compared to ultrasound alone. This clearly opens the door to new and innovative approaches to diagnose and treat the disease."

"Sentinelle is committed to leveraging the power of multi-modality imaging to bring needed tools to the clinician, to aid them in the diagnosis, treatment and management of cancer," said Cameron Piron, Sentinelle's President and CEO. "Aegis Navigation is an important step for Sentinelle as it extends our product line relevance into new clinical applications. We look forward to making the same impact as we did with Breast MRI."

About Sentinelle Medical Inc.

Sentinelle Medical is a leading manufacturer of breast MRI coils and 4D advanced visualization software, providing clinicians greater confidence in diagnosis and accuracy in intervention. The award winning Sentinelle Vanguard(R) breast coils for GE, Siemens and Toshiba MRIs provide excellent quality MR images, complete and open access for intervention, enhanced patient comfort and clinical workflow. Sentinelle's groundbreaking Aegis line of advanced 4D visualization software has been designed from the ground up to offer the clinician maximum control, and superior speed of interaction, within an intuitive and easy to use interface. Sentinelle's innovative product line also includes solutions for multimodality imaging, designed to solve the real world problems radiologists, technologists and oncologists encounter in their efforts for earlier detection and better treatment of cancer.

Sentinelle products are used in leading breast cancer and imaging centers throughout North America including Dartmouth-Hitchcock Medical Centre, H. Lee Moffitt Cancer Center and Research Institute, Mountain Medical Physician Specialists, Radiology Ltd., Scripps Memorial Hospital, Sunnybrook Health Sciences Centre, University Health Network and Windsong Radiology Group.

For more information, visit www.sentinellemedical.com

* Aegis(TM) Navigation is a work in progress, requires 510(k) pre-market review, and is not yet commercially available in the U.S

+ Study conducted under Health Canada Investigational Testing Applications

SOURCE Sentinelle Medical Inc.

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