Cbyon, Inc. Introduces Technology That Makes Patients Transparent

The Cbyon Suite Enables Minimally Invasive Surgery,

Offers Hospitals the Ability to Improve Patient Care and Reduce Hospital Costs



Apr 23, 2001, 01:00 ET from Cbyon, Inc.

    PALO ALTO, Calif., April 23 /PRNewswire Interactive News Release/ --
 Cbyon(R), Inc., a medical technology company, is introducing the Cbyon
 Suite(TM) at the annual meeting of the American Association of Neurological
 Surgeons (AANS), taking place this week in Toronto, Ontario, Canada.  The
 advanced image guidance system, which is optimized for use in neuro-, sinus-
 and spinal surgeries, is a featured topic of numerous meeting sessions.
     "Existing image guidance systems are helpful in localizing pathology
 within a patient, but have limited ability to help physicians fully visualize
 internal anatomy or easily orient the surgeon to the patient and to surgical
 tools during a minimally invasive procedure," stated Dr. Kim H. Manwaring,
 director of pediatric neurosurgery and neurosurgery research at Phoenix
 Children's Hospital (Phoenix, Ariz.), faculty member at Barrow Neurological
 Institute (Phoenix, Ariz.) and a speaker at one of the educational sessions.
 "The Cbyon Suite picks up where these systems leave off, offering physicians
 an intuitive, three-dimensional dynamic visualization of patient-specific
 anatomy.  It holds promise to help surgeon's perform even more procedures in a
 minimally invasive manner, improving patient care and reducing costs."
 
     CBYON SOFTWARE IS THE BASIS FOR CREATING A "SEE-THROUGH PATIENT"
     The Cbyon Suite is based on a proprietary software platform called
 Perspective Volume Rendering(TM), developed by biomedical engineers and
 surgeons from the Image Guidance Laboratory in Stanford University's
 Department of Neurosurgery.  This platform employs powerful mathematical
 algorithms and computer processors to render a 3-D representation of targeted
 patient anatomy using diagnostic imaging data acquired pre-operatively from
 computed tomography (CT), magnetic resonance imaging (MRI) or positron-
 emission tomography (PET) scans.  The Cbyon Suite then integrates the 3-D
 representation with a variety of virtual and actual surgical tools, enabling
 physicians to see inside the body as never before.
     "The Cbyon Suite allows physicians to create a working model of a
 patient's anatomy -- a 'virtual patient' that can be used pre-, intra- and
 post-operatively," stated Ramin Shahidi, PhD, director of Stanford's Image
 Guidance Laboratory and the scientific founder of Cbyon, Inc.  "Unlike
 existing image guidance systems which use only a portion of the available
 imaging data to produce surface rendered models, the Cbyon Suite maintains the
 integrity of the imaging data set during the rendering process.  As a result,
 physicians can view the computer model from any perspective -- even from the
 inside of the anatomy -- with a great degree of detail."
 
     CBYON SUITE OFFERS ONE-OF-A-KIND FEATURES
     The Cbyon Suite offers the basic capabilities provided by existing image
 guidance systems.  Additionally, due to the use of Perspective Volume
 Rendering, the system can offer a host of additional features and modules,
 including:
 
     -- Dynamic Data Filtering(TM):  This feature enables physicians to quickly
        and easily customize the view of the virtual patient's anatomy to their
        specific needs or preferences -- even make it transparent.  Physicians
        selectively alter the displayed opacity of structures in the virtual
        patient (a process known as image 'filtering') to emphasize, de-
        emphasize or remove anatomy in order to see through to the structures
        beyond.  For example, this process allows surgeons to visualize
        important structures that should be targeted or avoided during surgery.
        Cbyon has developed sets of frequently requested, pre-defined filters
        for use with specific surgical procedures and with standard kinds of
        medical imaging data.
 
     -- Virtual Endoscopy(TM):  This supplemental software module is part of a
        Cbyon workstation that is used in doctors' offices to help them plan
        and practice procedures prior to performing them.  This software works
        as though a camera and light are attached to the tip of a virtual
        surgical tool.  With it, physicians create a "tool's eye view" of a
        patient's internal anatomy and navigate through the virtual patient,
        simulating surgical approach and predicting and planning for
        intraoperative challenges.
 
        Using the software, physicians can also create cinematic fly-throughs
        of the surgical approach.  Watching a fluid 3-D movie on the Cbyon
        Suite display, a surgeon is able to see the internal structures of the
        virtual patient as if viewing them from the perspective of the surgical
        tool.  While in this mode, the physician can use the Dynamic Data
        Filtering feature to gain visual access to otherwise hidden anatomy.
 
     -- Virtual Endoscope(TM):  During surgery, the Cbyon Suite allows
        physicians to use any rigid instrument as a virtual endoscope,
        providing virtual endoscopic views from the tip of the instrument
        relative to its position within the patient.  Using this feature,
        surgeons can minimize the invasiveness of procedures, because they
        have a better understanding of each patient's unique anatomy.
 
     -- Virtual Fluoroscopy(TM):  This feature correlates surgical tool
        position with intraoperative fluoroscopic images.  In spinal procedures
        such as discectomy, vertebroplasty, vertebral fusion and pedicle screw
        placement, in which a surgeon would normally use a fluoroscope to plan
        and then execute the surgery, this feature allows the surgeon to
        simulate the fluoroscopy during the majority of the procedure, reducing
        the surgeon's and the patient's exposure to hazardous x-rays.
 
     -- Dynamic Image Synchronization(TM):  This feature is used during a
        surgical procedure and involves the overlay of intra-operative
        endoscopic images onto the Virtual Endoscopy display.  Also called
        "Image Enhanced Endoscopy", this feature enables a surgeon to use all
        of the capabilities of Dynamic Data Filtering and Virtual Endoscopy
        while viewing live images.  As a result, the surgeon has a dynamic
        guide to the actual patient's anatomy that provides visual access to
        previously hidden structures, assists in maintaining orientation and
        provides navigation guidance via an intuitive interface.
 
     THE CBYON SUITE IS IN USE AT LEADING SURGICAL FACILITIES NATIONWIDE
     Since Cbyon received FDA clearance for the Cbyon Suite in 2000, the
 company has been working with surgeons at leading institutions to optimize it
 in anticipation of a full commercial introduction.  Facilities currently using
 the system include Barrow Neurological Institute, Massachusetts General
 Hospital/Harvard Medical School and Stanford University.
     "Our sales, clinical and customer service teams are queued up to introduce
 the system to hospitals nationwide for the core neurosurgery, sinus surgery
 and spine surgery applications," stated Mitchell Seyedin, Ph.D., president and
 CEO of Cbyon.  "Concurrently, our R&D team is enhancing the system to
 accommodate integration of real-time ultrasound images, which would expand use
 of the system to include soft-tissue biopsy procedures and cardiac,
 gastrointestinal and gynecologic surgeries."
 
     ABOUT CBYON, INC.
     Cbyon, Inc. (Palo Alto, Calif.) is a medical technology company that
 develops and manufactures software, enabling surgeons to apply minimally
 invasive techniques to a variety of surgical procedures.  The company's first
 product is the Cbyon Suite, which has received 510(k) clearance by the Food
 and Drug Administration (FDA).  Cbyon is a privately funded company. For more
 information about Cbyon, log on to www.cbyon.com.
 
     Cbyon is a registered trademark of Cbyon, Inc.  Cbyon Suite, Perspective
 Volume Rendering, Dynamic Data Filtering, Virtual Endoscopy, Virtual
 Fluoroscopy and Dynamic Image Synchronization are trademarks of Cbyon, Inc.
 
     For further information please contact media, Julie Sullivan, ext. 105,
 jsullivan@fischerhealth.com, or Krista Lambly, ext. 125,
 klambly@fischerhealth.com, both of Fischer & Partners, Inc., 310-577-7870, for
 Cbyon, Inc.; or investors, Shirley Clayton, Chief Financial Officer of Cbyon,
 Inc., 650-842-1800, ext. 1711.
 
                     MAKE YOUR OPINION COUNT -  Click Here
                http://tbutton.prnewswire.com/prn/11690X76217512
 
 

SOURCE Cbyon, Inc.
    PALO ALTO, Calif., April 23 /PRNewswire Interactive News Release/ --
 Cbyon(R), Inc., a medical technology company, is introducing the Cbyon
 Suite(TM) at the annual meeting of the American Association of Neurological
 Surgeons (AANS), taking place this week in Toronto, Ontario, Canada.  The
 advanced image guidance system, which is optimized for use in neuro-, sinus-
 and spinal surgeries, is a featured topic of numerous meeting sessions.
     "Existing image guidance systems are helpful in localizing pathology
 within a patient, but have limited ability to help physicians fully visualize
 internal anatomy or easily orient the surgeon to the patient and to surgical
 tools during a minimally invasive procedure," stated Dr. Kim H. Manwaring,
 director of pediatric neurosurgery and neurosurgery research at Phoenix
 Children's Hospital (Phoenix, Ariz.), faculty member at Barrow Neurological
 Institute (Phoenix, Ariz.) and a speaker at one of the educational sessions.
 "The Cbyon Suite picks up where these systems leave off, offering physicians
 an intuitive, three-dimensional dynamic visualization of patient-specific
 anatomy.  It holds promise to help surgeon's perform even more procedures in a
 minimally invasive manner, improving patient care and reducing costs."
 
     CBYON SOFTWARE IS THE BASIS FOR CREATING A "SEE-THROUGH PATIENT"
     The Cbyon Suite is based on a proprietary software platform called
 Perspective Volume Rendering(TM), developed by biomedical engineers and
 surgeons from the Image Guidance Laboratory in Stanford University's
 Department of Neurosurgery.  This platform employs powerful mathematical
 algorithms and computer processors to render a 3-D representation of targeted
 patient anatomy using diagnostic imaging data acquired pre-operatively from
 computed tomography (CT), magnetic resonance imaging (MRI) or positron-
 emission tomography (PET) scans.  The Cbyon Suite then integrates the 3-D
 representation with a variety of virtual and actual surgical tools, enabling
 physicians to see inside the body as never before.
     "The Cbyon Suite allows physicians to create a working model of a
 patient's anatomy -- a 'virtual patient' that can be used pre-, intra- and
 post-operatively," stated Ramin Shahidi, PhD, director of Stanford's Image
 Guidance Laboratory and the scientific founder of Cbyon, Inc.  "Unlike
 existing image guidance systems which use only a portion of the available
 imaging data to produce surface rendered models, the Cbyon Suite maintains the
 integrity of the imaging data set during the rendering process.  As a result,
 physicians can view the computer model from any perspective -- even from the
 inside of the anatomy -- with a great degree of detail."
 
     CBYON SUITE OFFERS ONE-OF-A-KIND FEATURES
     The Cbyon Suite offers the basic capabilities provided by existing image
 guidance systems.  Additionally, due to the use of Perspective Volume
 Rendering, the system can offer a host of additional features and modules,
 including:
 
     -- Dynamic Data Filtering(TM):  This feature enables physicians to quickly
        and easily customize the view of the virtual patient's anatomy to their
        specific needs or preferences -- even make it transparent.  Physicians
        selectively alter the displayed opacity of structures in the virtual
        patient (a process known as image 'filtering') to emphasize, de-
        emphasize or remove anatomy in order to see through to the structures
        beyond.  For example, this process allows surgeons to visualize
        important structures that should be targeted or avoided during surgery.
        Cbyon has developed sets of frequently requested, pre-defined filters
        for use with specific surgical procedures and with standard kinds of
        medical imaging data.
 
     -- Virtual Endoscopy(TM):  This supplemental software module is part of a
        Cbyon workstation that is used in doctors' offices to help them plan
        and practice procedures prior to performing them.  This software works
        as though a camera and light are attached to the tip of a virtual
        surgical tool.  With it, physicians create a "tool's eye view" of a
        patient's internal anatomy and navigate through the virtual patient,
        simulating surgical approach and predicting and planning for
        intraoperative challenges.
 
        Using the software, physicians can also create cinematic fly-throughs
        of the surgical approach.  Watching a fluid 3-D movie on the Cbyon
        Suite display, a surgeon is able to see the internal structures of the
        virtual patient as if viewing them from the perspective of the surgical
        tool.  While in this mode, the physician can use the Dynamic Data
        Filtering feature to gain visual access to otherwise hidden anatomy.
 
     -- Virtual Endoscope(TM):  During surgery, the Cbyon Suite allows
        physicians to use any rigid instrument as a virtual endoscope,
        providing virtual endoscopic views from the tip of the instrument
        relative to its position within the patient.  Using this feature,
        surgeons can minimize the invasiveness of procedures, because they
        have a better understanding of each patient's unique anatomy.
 
     -- Virtual Fluoroscopy(TM):  This feature correlates surgical tool
        position with intraoperative fluoroscopic images.  In spinal procedures
        such as discectomy, vertebroplasty, vertebral fusion and pedicle screw
        placement, in which a surgeon would normally use a fluoroscope to plan
        and then execute the surgery, this feature allows the surgeon to
        simulate the fluoroscopy during the majority of the procedure, reducing
        the surgeon's and the patient's exposure to hazardous x-rays.
 
     -- Dynamic Image Synchronization(TM):  This feature is used during a
        surgical procedure and involves the overlay of intra-operative
        endoscopic images onto the Virtual Endoscopy display.  Also called
        "Image Enhanced Endoscopy", this feature enables a surgeon to use all
        of the capabilities of Dynamic Data Filtering and Virtual Endoscopy
        while viewing live images.  As a result, the surgeon has a dynamic
        guide to the actual patient's anatomy that provides visual access to
        previously hidden structures, assists in maintaining orientation and
        provides navigation guidance via an intuitive interface.
 
     THE CBYON SUITE IS IN USE AT LEADING SURGICAL FACILITIES NATIONWIDE
     Since Cbyon received FDA clearance for the Cbyon Suite in 2000, the
 company has been working with surgeons at leading institutions to optimize it
 in anticipation of a full commercial introduction.  Facilities currently using
 the system include Barrow Neurological Institute, Massachusetts General
 Hospital/Harvard Medical School and Stanford University.
     "Our sales, clinical and customer service teams are queued up to introduce
 the system to hospitals nationwide for the core neurosurgery, sinus surgery
 and spine surgery applications," stated Mitchell Seyedin, Ph.D., president and
 CEO of Cbyon.  "Concurrently, our R&D team is enhancing the system to
 accommodate integration of real-time ultrasound images, which would expand use
 of the system to include soft-tissue biopsy procedures and cardiac,
 gastrointestinal and gynecologic surgeries."
 
     ABOUT CBYON, INC.
     Cbyon, Inc. (Palo Alto, Calif.) is a medical technology company that
 develops and manufactures software, enabling surgeons to apply minimally
 invasive techniques to a variety of surgical procedures.  The company's first
 product is the Cbyon Suite, which has received 510(k) clearance by the Food
 and Drug Administration (FDA).  Cbyon is a privately funded company. For more
 information about Cbyon, log on to www.cbyon.com.
 
     Cbyon is a registered trademark of Cbyon, Inc.  Cbyon Suite, Perspective
 Volume Rendering, Dynamic Data Filtering, Virtual Endoscopy, Virtual
 Fluoroscopy and Dynamic Image Synchronization are trademarks of Cbyon, Inc.
 
     For further information please contact media, Julie Sullivan, ext. 105,
 jsullivan@fischerhealth.com, or Krista Lambly, ext. 125,
 klambly@fischerhealth.com, both of Fischer & Partners, Inc., 310-577-7870, for
 Cbyon, Inc.; or investors, Shirley Clayton, Chief Financial Officer of Cbyon,
 Inc., 650-842-1800, ext. 1711.
 
                     MAKE YOUR OPINION COUNT -  Click Here
                http://tbutton.prnewswire.com/prn/11690X76217512
 
 SOURCE  Cbyon, Inc.