Global Next Generation Sequencers - Clinical Diagnostics

LONDON, April 26, 2017 /PRNewswire/ -- The Global market is additionally analyzed by the following End-Use Segments: Pharmaceutical/Biotech, Industrial, and Government/Academia. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World. Annual estimates and forecasts are provided for the period 2015 through 2022. Also, a six-year historic analysis is provided for these markets. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs.

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The report profiles 93 companies including many key and niche players such as -

- Agilent Technologies Inc.

- Becton, Dickinson and Company

- Fluidigm Corporation

- Genomatix GmbH

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I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

Study Reliability and Reporting LimitationsDisclaimersData Interpretation & Reporting LevelQuantitative Techniques & AnalyticsProduct Definitions and Scope of Study

II. EXECUTIVE SUMMARY

1. OVERVIEWNext Generation Sequencing Techniques Transform the Genomics SpaceNext Generation Sequencers (NGS): A High-Throughput Sequencing TechnologyUS Leads the NGS Market, Asia-Pacific to Foster Future GrowthAcademic & Research Dominates NGS MarketOncology Testing - The Application with Most Promising Opportunities for NGS TechnologyDeclining Cost of Sequencing to Fuel Adoption of NGS SystemsTable 1: Cost Per Genome Sequencing in $ for the Years 2000 through 2016 (includes corresponding Graph/Chart)After Dramatic Price Declines, Is NGS Market Positioned for Further Disruption?2. COMPETITIVE LANDSCAPEA Highly Competitive MarketplaceIllumina Leads the Global NGS MarketIllumina's NGS Instruments Portfolio - A ComparisonTable 2: Leading Vendors in the Global NGS Market (2016E): Percentage Breakdown of Installed Base for Illumina, Life Technologies/Thermo Fisher, and Others (includes corresponding Graph/Chart)Table 3: Leading Players in the Global NGS Instruments & Consumables Market (2016E): Percentage Breakdown of Revenues for Illumina, Life Technologies/Thermo Fisher, Pacific Biosciences and Others (includes corresponding Graph/Chart)A Glance at the Major NGS Platforms in UseKey NGS Platforms on the Market3. GROWTH DRIVERS, MARKET TRENDS & ISSUESExpanding Applications of NGS TechnologyNGS Revolutionizes Drug Discovery and Development SpaceGenetic Information offered by NGS Aids in Drug Development ProcessRevolutionary Capabilities of NGS Technology to Play a Vital Part in Advancement of Precision MedicineRising Incidences of Cancer & Benefits of Personalized Cancer Therapy to Propel NGS MarketComparison of Sanger Sequencing, Real-time PCR Sequencing and Next Generation Sequencing Methods for Identification of Driver MutationsKey Cancer StatisticsTable 4: Worldwide Incidence of Cancer: Number of New Cases Diagnosed for the Years 2013, 2020 & 2030 (includes corresponding Graph/Chart)Table 5: New Cancer Cases in the World by Affected Site (2012) (In Thousands) (includes corresponding Graph/Chart)Table 6: Common Cause of Cancer Deaths Worldwide - Number of Deaths due to Select Types of Cancer for 2015 (includes corresponding Graph/Chart)NGS Emerges as a Game Changing Technology for Precision OncologyPersonalized Medicine: Growing Prominence of NGS in Providing Customized Treatments to PatientsGrowing Significance of NGS in Enabling Personalized Oncology - Timeline of Major Developments in Sequencing Technologies & Applications Related to OncologyPersonal Genomics Services - Blessing or Bane?NGS Technology Drives RNA Sequencing in TranscriptomicsLonger Reach of a Read: A Key Feature Considered for SequencingqPCR - The Core Technique in NGS TechniqueDevelopment of New Systems & Platforms to Fuel NGS UtilizationAdvancements in Next Generation Sequencing (NGS) Technology Fuel AdoptionDevelopment Efforts Intensify in Long-Read SequencingSingle-Cell Genomics: A Promising Application of NGS TechnologyShift from Tumor Biopsies to Cancer Liquid BiopsiesNGS Enhances Study of Antimicrobial ResistanceEffective Use of NGS Tools in Public Healthcare SystemsE-Infrastructure for Storage & Analysis of NGS DataExplosive Growth in Sequencing Data Drives Focus onto Cloud ComputingNGS Hold an Edge Over CE Sequencing MethodStandardization of NGS Technique: A Critical Requirement for Wider AdoptionChallenges Confronting High-throughput Sequencing MarketHigh Machine Costs and Licensure FeesLack of Skilled PersonnelAbsence of Regulatory FrameworkLimited Access to Scientific Literature and InternetSuboptimal Outsourcing ServicesRegulations Related to NGS-Based TestsInnovative TechnologiesNanopore Sequence TechnologySingle-Molecule Real-Time technology (SMRT)Direct Genomics' Single Molecule SequencingTruSPADES Simplifies Metagenomics SequencingGnuBIO PlatformElectron Microscopy DNA SequencingFRET-based DNA SequencingIdentification/Sequencing using Mechanical PropertiesMALDI-TOF MSRNAP Sequencing MethodTunneling Currents DNA SequencingqPCR-Driven Library Quantitation Saves Time and OverheadsAchieving Trans-Block UniformityEnhancing qPCR Precision4. TECHNOLOGY OVERVIEWSanger Sequencing (Dideoxy Sequencing)Evolution of Next Generation SequencingNGS versus MicroarraysImportant Factors to Consider Before Choosing NGS PlatformsNGS - Major Application AreasWhole Genome SequencingExome sequencingTargeted ResequencingRNA sequencing (RNA-Seq)Chromatin immunoprecipitation sequencing (ChIP-Seq)5. PRODUCT INNOVATIONS/INTRODUCTIONSQIAGEN Launches Novel QIAseq NGS PanelsBD Launches BD CLiC™ SystemImmucor and Sirona Genomics Launch MIA FORA NGSbioMérieux and Illumina Launch bioMérieux EpiSeq NGS ServiceBioline Introduces JetSeq™ Kit for NGS Sample PreparationOxford Gene Technology Launches SureSeq™ NGS SolutionsGENEWIZ Launches FuzeSeq™ Antibody Sequencing TechnologySage Science Launches PippinHT Automated Instruments for Use with NGSBGI Tech to Launch Two Ranges of NGS - X Bio and IntelligenThermo Fisher Scientific Introduces Clinical NGS Oncology Quality ControlVela Diagnostics Announces Pre-launch of Automated NGSRubicon Genomics Launches PicoPLEX™ DNA-seq Kits for Use with NGS Platforms6. RECENT INDUSTRY ACTIVITYMayo Clinic Collaborates with Illumina on NGSSophia Genetics Enters into Partnership with IlluminaNovogene Enters into Collaboration with AITbiotechNatera Extends Supply Agreement with IlluminaArcherDX Enters into Collaboration with IlluminaTBUSH to Acquire WaferGen Bio-systemsAdvanced Biological Laboratories Signs Distribution Agreement with Thermo Fisher ScientificBio-Rad Enters into Partnership with IlluminaSYGNIS AG Signs Distribution Agreement with LucigenAlmac Diagnostics Enters into Collaboration with IlluminaRoche Acquires Kapa BiosystemsQIAGEN Expands Partnership with BGIIntel Enters into Partnership with Edico GenomeIllumina Enters into Partnership with Merck SeronoLockheed Martin and Illumina Enter into PartnershipWuXi PharmaTech Acquires NextCODE HealthRoche Acquires Bina TechnologiesCollabRx Enters into Partnership with CartageniaNew England Biolabs and Directed Genomics Enter into PartnershipReprogenetics Partners with IlluminaBD Acquires GenCell BiosystemsAB SCIEX and Illumina Enter into OneOmics™ Partnership ProjectThermo Fisher Scientific, GSK, and Pfizer Enter into Agreement to Develop NGSAstraZeneca Collaborates with IlluminaRoche Acquires Genia Technologies7. FOCUS ON SELECT GLOBAL PLAYERSAgilent Technologies Inc. (US)Becton, Dickinson and Company (BD) (US)Fluidigm Corporation (US)Genomatix GmbH (Germany)Illumina, Inc. (US)Oxford Gene Technology (UK)Oxford Nanopore Technologies (UK)Pacific Biosciences of California, Inc. (US)QIAGEN N.V. (The Netherlands)RainDance Technologies, Inc. (US)Roche Sequencing (US)Shenzhen BGI Diagnosis Co., Ltd. (China)Thermo Fisher Scientific, Inc. (US)8. GLOBAL MARKET PERSPECTIVETable 7: World Recent Past, Current & Future Analysis for Next Generation Sequencers by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)Table 8: World Historic Review for Next Generation Sequencers by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)Table 9: World 14-Year Perspective for Next Generation Sequencers by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World Markets for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart)Table 10: World Recent Past, Current & Future Analysis for Next Generation Sequencers by End-Use Industry - Pharmaceuticals/Biotech, Industrial, and Government/Academia Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)Table 11: World Historic Review for Next Generation Sequencers by End-Use Industry - Pharmaceuticals/ Biotech, Industrial, and Government/Academia Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)Table 12: World 14-Year Perspective for Next Generation Sequencers by End-Use Industry - Percentage Breakdown of Dollar Sales for Pharmaceuticals/Biotech, Industrial, and Government/Academia Markets for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart)

III. MARKET

1. THE UNITED STATESA.Market AnalysisMarket OverviewFDA Regulations on NGS-Based TestsSequencing Applications Drive the US Genomics MarketNGS for Clinical Oncology - A Promising Area of GrowthProduct LaunchesStrategic Corporate DevelopmentsSelect Key PlayersB.Market AnalyticsTable 13: US Recent Past, Current & Future Analysis for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)Table 14: US Historic Review for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)2. CANADAMarket AnalysisTable 15: Canadian Recent Past, Current & Future Analysis for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)Table 16: Canadian Historic Review for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)3. JAPANA.Market AnalysisCurrent and Future AnalysisStrategic Corporate DevelopmentB.Market AnalyticsTable 17: Japanese Recent Past, Current & Future Analysis for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)Table 18: Japanese Historic Review for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)4. EUROPEA.Market AnalysisMarket OverviewB.Market AnalyticsTable 19: European Recent Past, Current & Future Analysis for Next Generation Sequencers by Geographic Region/Country - France, Germany, Italy, UK, Spain, Russia, and Rest of European Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)Table 20: European Historic Review for Next Generation Sequencers by Geographic Region/Country - France, Germany, Italy, UK, Spain, Russia, and Rest of European Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)Table 21: European 14-Year Perspective for Next Generation Sequencers by Geographic Region/Country - Percentage Breakdown of Dollar Sales for France, Germany, Italy, UK, Spain, Russia, and Rest of European Markets for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart)

4a. FRANCE

Market Analysis

Table 22: French Recent Past, Current & Future Analysis for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)

Table 23: French Historic Review for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)

4b. GERMANYA.Market AnalysisCurrent and Future AnalysisGenomatix GmbH - A Key PlayerB.Market AnalyticsTable 24: German Recent Past, Current & Future Analysis for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)Table 25: German Historic Review for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)

4c. ITALY

Market Analysis

Table 26: Italian Recent Past, Current & Future Analysis for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)

Table 27: Italian Historic Review for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)

4d. THE UNITED KINGDOMA.Market AnalysisCurrent and Future AnalysisProduct LaunchStrategic Corporate DevelopmentSelect Key PlayersB.Market AnalyticsTable 28: UK Recent Past, Current & Future Analysis for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)Table 29: UK Historic Review for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)

4e. SPAIN

Market Analysis

Table 30: Spanish Recent Past, Current & Future Analysis for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)

Table 31: Spanish Historic Review for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)

4f. RUSSIAMarket AnalysisTable 32: Russian Recent Past, Current & Future Analysis for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)Table 33: Russian Historic Review for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)

4g. REST OF EUROPE

A.Market Analysis

Current and Future Analysis

Product Launch

Strategic Corporate Developments

QIAGEN N.V. (Netherlands) - A Key Player

B.Market Analytics

Table 34: Rest of European Recent Past, Current & Future Analysis for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)

Table 35: Rest of European Historic Review for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)

5. ASIA-PACIFICMarket AnalysisTable 36: Asia-Pacific Recent Past, Current & Future Analysis for Next Generation Sequencers by Geographic Region/Country - China, and Rest of Asia-Pacific Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)Table 37: Asia-Pacific Historic Review for Next Generation Sequencers by Geographic Region/Country - China, and Rest of Asia-Pacific Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)Table 38: Asia-Pacific 14-Year Perspective for Next Generation Sequencers by Geographic Region/Country - Percentage Breakdown of Dollar Sales for China, and Rest of Asia-Pacific Markets for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart)

5a. CHINA

A.Market Analysis

Current and Future Analysis

Strategic Corporate Development

Shenzhen BGI Diagnosis Co., Ltd. - A Key Player

B.Market Analytics

Table 39: Chinese Recent Past, Current & Future Analysis for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)

Table 40: Chinese Historic Review for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)

5b. REST OF ASIA-PACIFICA.Market AnalysisCurrent and Future AnalysisStrategic Corporate DevelopmentB.Market AnalyticsTable 41: Rest of Asia-Pacific Recent Past, Current & Future Analysis for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)Table 42: Rest of Asia-Pacific Historic Review for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)6. LATIN AMERICAMarket AnalysisTable 43: Latin American Recent Past, Current & Future Analysis for Next Generation Sequencers by Geographic Region/Country - Brazil, and Rest of Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)Table 44: Latin American Historic Review for Next Generation Sequencers by Geographic Region/Country - Brazil, and Rest of Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)Table 45: Latin American 14-Year Perspective for Next Generation Sequencers by Geographic Region/Country - Percentage Breakdown of Dollar Sales for Brazil, and Rest of Latin America Markets for Years 2009, 2016 and 2022 (includes corresponding Graph/Chart)7. REST OF WORLDMarket AnalysisTable 46: Rest of World Recent Past, Current & Future Analysis for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2015 through 2022 (includes corresponding Graph/Chart)Table 47: Rest of World Historic Review for Next Generation Sequencers Market Analyzed with Annual Sales Figures in US$ Thousand for Years 2009 through 2014 (includes corresponding Graph/Chart)

IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 93 (including Divisions/Subsidiaries - 104) The United States (61) Canada (3) Japan (2) Europe (27) - France (1) - Germany (7) - The United Kingdom (5) - Rest of Europe (14) Asia-Pacific (Excluding Japan) (11)

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