Pfenex Inc. - A New Independent Company That Will Enable Rapid, Cost Effective Production of Recombinant Proteins

Dec 08, 2009, 12:27 ET from Pfenex Inc.

SAN DIEGO, Dec. 8 /PRNewswire/ -- Pfenex Inc. announced today that it has been formally spun-out of The Dow Chemical Company as an independent venture backed entity. The new company, headquartered in San Diego, California, is based on Pfenex Expression Technology(TM), a robust Pseudomonas fluorescens-based platform that uses high throughput, parallel processing methodologies for optimized protein production.

Pfenex will focus on applying the Pfenex Expression Technology(TM) platform in a variety of protein production applications including proteins for discovery applications, human therapeutics and vaccines, reagent proteins including diagnostics, and biosimilars.

Pfenex Inc.'s CEO, Bertrand C. Liang commented, "We are pleased to have Signet as a partner as we expand the Pfenex businesses, and create new opportunities across the product development value chain."

The new company will consist of a team of over 20 scientists, a complete process development and protein production facility supported by a comprehensive bio-analytical capability and a significant intellectual property estate covering the Pfenex Expression Technology(TM) platform, Virus-Like Particle Technology and protein recovery technologies.

The lead investor in the new company is Signet Healthcare Partners, an experienced venture capital investor focused on the healthcare sector. Financial terms were not disclosed.

"We are very impressed with Pfenex management, its intellectual property estate and its proven technology platform," stated Al Hansen, Managing Director of Signet. "We think the combination of these three elements can significantly lower the cost of producing existing proteins as well as surmount existing barriers to the manufacture of new, complex proteins."

About Pfenex Inc.

Pfenex is a protein production company leveraging the unique and powerful Pfenex Expression Technology(TM) platform based on the microorganism Pseudomonas fluorescens, for the production of research proteins, reagent proteins, biosimilars and innovator biopharmaceuticals. For more information please visit

About Signet Healthcare Partners

Signet Healthcare Partners was founded in 1998 and has a team that brings over 100 years of collective experience in the biopharmaceutical, medical device, private equity and investment banking businesses. Signet Healthcare has maintained its dedicated focus to diversified healthcare investing - primarily serving as lead investor to expansion stage companies engaged in specialty pharmaceuticals, medical devices and biopharmaceutical services.

SOURCE Pfenex Inc.