Study Results Suggest Aspirin as Effective as Prescription Tylenol(R) on Pain

Patients May Be Able to Forego Costly Prescription Medications



Apr 21, 2001, 01:00 ET from Bayer Corporation

    PHOENIX, April 21 /PRNewswire Interactive Press Release/ -- Extra Strength
 Bayer Aspirin(R) is as effective in treating severe headaches as
 one of the most commonly prescribed pain medications, Tylenol(R) with Codeine
 #3, according to study results presented today at the 20th Annual Scientific
 Meeting of the American Pain Society in Phoenix.
     "Millions of people worldwide suffer the excruciating pain associated with
 severe tension headaches and may unnecessarily be taking costly prescription
 medications to treat them when aspirin is equally effective," said Laureen
 MacEachern, Ph.D., Clinical Affairs, Bayer Consumer Care. "Don't let the fact
 that aspirin is more than 100 years old fool you.  People around the world
 have known for a long time what a great pain reliever aspirin can be."
     An analysis of 115 patients with severe tension headache pain compared the
 efficacy of two Extra Strength Bayer Aspirin (1,000 mg total) to the most
 commonly prescribed dose of Tylenol with Codeine #3 (300 mg acetaminophen/30
 mg codeine) and placebo.  Study results suggest that both Extra Strength Bayer
 Aspirin and Tylenol with Codeine #3 were significantly more effective and
 provided significantly more pain relief than placebo.  Data also indicated
 that Extra Strength Bayer Aspirin and Tylenol with Codeine #3 were comparable
 for all efficacy and safety evaluations.
     "Aspirin is just as effective and is much less expensive than prescription
 alternatives," said MacEachern.  "One dose of Extra Strength Bayer Aspirin
 costs approximately $0.15 for two pills versus about $8.99 for one
 prescription Tylenol with Codeine tablet."
     In this randomized, double-blind, single-dose study, male and female
 patients with a history of at least two but no more than 10 tension headaches
 per month and presented with severe pain were evaluated.  Tension headache is
 a condition involving pain or discomfort in the head, scalp, temples or back
 of the neck; usually associated with muscle tightness in these areas; and can
 be worsened or triggered by stress, fatigue, noise or glare.  Pain evaluations
 were conducted at 30 minutes and then every hour over six hours after dosing.
 Patients were asked to evaluate pain intensity (none, mild, moderate or
 severe) and pain relief (no relief, headache pain less than half gone, half
 gone, more than half gone or complete relief).  Extra Strength Bayer Aspirin
 and Tylenol with Codeine #3 provided significant and statistically comparable
 pain relief from two through six hours after dosing.
     Other than cost, there are many other important reasons to differentiate
 aspirin from other pain relievers, especially acetaminophen, the active
 ingredient in products like Tylenol.  Aspirin has been used effectively by
 millions of people for more than 100 years and does not have the same adverse
 effect on the liver as acetaminophen.  The most important side effects of
 aspirin are gastrointestinal.  As this study has shown, aspirin is equally
 effective in pain relief as Tylenol with Codeine #3, but it also is noted for
 its ability to fight inflammation, which acetaminophen cannot do.  And, used
 regularly, aspirin has benefits beyond any other pain relievers in its ability
 to prevent recurrent heart attacks and strokes.
     Regular use of aspirin is not appropriate for everyone.  People should be
 sure to talk to their doctors before beginning an aspirin regimen.  Medical
 studies have shown that a very small percentage of the population, less than 6
 percent, cannot take aspirin due to stomach irritation.  Patients who are
 predisposed to gastric problems or have a history of stomach ulcers should not
 take aspirin unless directed by a physician.  People who experience stomach
 irritation should ask their doctor whether an enteric coated or buffered
 aspirin product might help reduce the incidence of stomach related side
 effects.  In almost all cases, aspirin's benefits significantly outweigh its
 risks when taken as directed.  Patients who have questions about which pain
 reliever to use should talk to their physicians.
     Best known for its flagship product, Bayer Aspirin(R), Bayer Corporation
 produces a broad range of health care, life sciences and chemical products
 that help diagnose and treat diseases, purify water, preserve local landmarks,
 protect crops, advance automobile safety and durability and improve people's
 lives.
     Headquartered in Pittsburgh, Bayer Corporation had sales of $10.1 billion
 in 2000 and is one of Fortune magazine's Most Admired Companies.  The company
 employs 23,200 people.  It is a member of the worldwide Bayer Group, a
 $29 billion international life sciences, polymers and specialty chemicals
 group based in Leverkusen, Germany.  The Bayer Group (BAYG.DE) stock is a
 component of the DAX, and Bayer plans to list its stock on the New York Stock
 Exchange on September 26, 2001.
 
     Tylenol is a registered trademark of McNeil Consumer Healthcare.
 
     For more information, contact:  Jennifer Furey of Golin-Harris
 International, 312-729-4277, for Bayer Corporation.
 
                     MAKE YOUR OPINION COUNT -  Click Here
                http://tbutton.prnewswire.com/prn/11690X89760309
 
 

SOURCE Bayer Corporation
    PHOENIX, April 21 /PRNewswire Interactive Press Release/ -- Extra Strength
 Bayer Aspirin(R) is as effective in treating severe headaches as
 one of the most commonly prescribed pain medications, Tylenol(R) with Codeine
 #3, according to study results presented today at the 20th Annual Scientific
 Meeting of the American Pain Society in Phoenix.
     "Millions of people worldwide suffer the excruciating pain associated with
 severe tension headaches and may unnecessarily be taking costly prescription
 medications to treat them when aspirin is equally effective," said Laureen
 MacEachern, Ph.D., Clinical Affairs, Bayer Consumer Care. "Don't let the fact
 that aspirin is more than 100 years old fool you.  People around the world
 have known for a long time what a great pain reliever aspirin can be."
     An analysis of 115 patients with severe tension headache pain compared the
 efficacy of two Extra Strength Bayer Aspirin (1,000 mg total) to the most
 commonly prescribed dose of Tylenol with Codeine #3 (300 mg acetaminophen/30
 mg codeine) and placebo.  Study results suggest that both Extra Strength Bayer
 Aspirin and Tylenol with Codeine #3 were significantly more effective and
 provided significantly more pain relief than placebo.  Data also indicated
 that Extra Strength Bayer Aspirin and Tylenol with Codeine #3 were comparable
 for all efficacy and safety evaluations.
     "Aspirin is just as effective and is much less expensive than prescription
 alternatives," said MacEachern.  "One dose of Extra Strength Bayer Aspirin
 costs approximately $0.15 for two pills versus about $8.99 for one
 prescription Tylenol with Codeine tablet."
     In this randomized, double-blind, single-dose study, male and female
 patients with a history of at least two but no more than 10 tension headaches
 per month and presented with severe pain were evaluated.  Tension headache is
 a condition involving pain or discomfort in the head, scalp, temples or back
 of the neck; usually associated with muscle tightness in these areas; and can
 be worsened or triggered by stress, fatigue, noise or glare.  Pain evaluations
 were conducted at 30 minutes and then every hour over six hours after dosing.
 Patients were asked to evaluate pain intensity (none, mild, moderate or
 severe) and pain relief (no relief, headache pain less than half gone, half
 gone, more than half gone or complete relief).  Extra Strength Bayer Aspirin
 and Tylenol with Codeine #3 provided significant and statistically comparable
 pain relief from two through six hours after dosing.
     Other than cost, there are many other important reasons to differentiate
 aspirin from other pain relievers, especially acetaminophen, the active
 ingredient in products like Tylenol.  Aspirin has been used effectively by
 millions of people for more than 100 years and does not have the same adverse
 effect on the liver as acetaminophen.  The most important side effects of
 aspirin are gastrointestinal.  As this study has shown, aspirin is equally
 effective in pain relief as Tylenol with Codeine #3, but it also is noted for
 its ability to fight inflammation, which acetaminophen cannot do.  And, used
 regularly, aspirin has benefits beyond any other pain relievers in its ability
 to prevent recurrent heart attacks and strokes.
     Regular use of aspirin is not appropriate for everyone.  People should be
 sure to talk to their doctors before beginning an aspirin regimen.  Medical
 studies have shown that a very small percentage of the population, less than 6
 percent, cannot take aspirin due to stomach irritation.  Patients who are
 predisposed to gastric problems or have a history of stomach ulcers should not
 take aspirin unless directed by a physician.  People who experience stomach
 irritation should ask their doctor whether an enteric coated or buffered
 aspirin product might help reduce the incidence of stomach related side
 effects.  In almost all cases, aspirin's benefits significantly outweigh its
 risks when taken as directed.  Patients who have questions about which pain
 reliever to use should talk to their physicians.
     Best known for its flagship product, Bayer Aspirin(R), Bayer Corporation
 produces a broad range of health care, life sciences and chemical products
 that help diagnose and treat diseases, purify water, preserve local landmarks,
 protect crops, advance automobile safety and durability and improve people's
 lives.
     Headquartered in Pittsburgh, Bayer Corporation had sales of $10.1 billion
 in 2000 and is one of Fortune magazine's Most Admired Companies.  The company
 employs 23,200 people.  It is a member of the worldwide Bayer Group, a
 $29 billion international life sciences, polymers and specialty chemicals
 group based in Leverkusen, Germany.  The Bayer Group (BAYG.DE) stock is a
 component of the DAX, and Bayer plans to list its stock on the New York Stock
 Exchange on September 26, 2001.
 
     Tylenol is a registered trademark of McNeil Consumer Healthcare.
 
     For more information, contact:  Jennifer Furey of Golin-Harris
 International, 312-729-4277, for Bayer Corporation.
 
                     MAKE YOUR OPINION COUNT -  Click Here
                http://tbutton.prnewswire.com/prn/11690X89760309
 
 SOURCE  Bayer Corporation