NEW YORK, October 14, 2013 /PRNewswire/ --
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Today, Analysts' Corner announced new research reports highlighting Gilead Sciences Inc. (NASDAQ: GILD), Celgene Corporation (NASDAQ: CELG), Ariad Pharmaceuticals Inc. (NASDAQ: ARIA), Puma Biotechnology, Inc. (NYSE: PBYI), and Dyax Corp. (NASDAQ: DYAX). Today's readers may access these reports free of charge - including full price targets, industry analysis and analyst ratings - via the links below.
Gilead Sciences Inc. Research Report
On October 9, 2013, Gilead Sciences Inc. (Gilead) announced that its Phase 3 study (Study 116) evaluating idelalisib in previously-treated chronic lymphocytic leukemia (CLL) patients who are not fit for chemotherapy will be stopped early. According to Gilead, it has already informed the US Food and Drug Administration about its plan to end the study, which came in after the recommendation by an independent Data Monitoring Committee (DMC) that was based on a predefined interim analysis showing highly statistically significant efficacy for the primary endpoint of progression-free survival in patients receiving idelalisib plus rituximab compared to those receiving rituximab alone. Gilead reported that the safety profile of idelalisib was acceptable and consistent with prior experience in combination with rituximab in previously treated CLL. The Full Research Report on Gilead Sciences Inc. - including full detailed breakdown, analyst ratings and price targets - is available to download free of charge at: [http://www.AnalystsCorner.com/r/full_research_report/9898_GILD]
Celgene Corporation Research Report
On October 3, 2013, Celgene Corporation (Celgene) reported that its wholly owned subsidiary, Celgene International Sàrl (Celgene International), has released results of pre-specified sub-analyses from ESTEEM 1 on nail and scalp psoriasis, as well as health-related quality-of-life outcomes, from the Company's first phase III study in psoriasis. Celgene International presented the study results at the 22nd Congress of the European Academy of Dermatology and Venereology annual meeting in Istanbul, Turkey. Professor Kristian Reich, M.D., SCIderm Research Institute and Dermatologikum, Hamburg, Germany, commented, "These analyses demonstrate that apremilast may improve these conditions and may offer a much-needed new oral treatment option for psoriasis patients. Moreover, the encouraging health-related quality-of-life findings suggest that long-term treatment with oral apremilast may improve the mental and physical well-being of these patients." The Full Research Report on Celgene Corporation - including full detailed breakdown, analyst ratings and price targets - is available to download free of charge at: [http://www.AnalystsCorner.com/r/full_research_report/7f47_CELG]
Ariad Pharmaceuticals Inc. Research Report
On October 9, 2013, ARIAD Pharmaceuticals Inc. (Ariad) announced results of its review of updated clinical data from the pivotal PACE trial of Iclusig (ponatinib) and actions that it is taking following consultations with the US Food and Drug Administration (FDA). Harvey J. Berger, M.D., Chairman and CEO of Ariad, stated, "We believe that the actions we are taking will help us ensure the most appropriate and safe use of Iclusig. With two years of follow up, we have learned a great deal about both the efficacy and safety of Iclusig in patients with Philadelphia-positive leukemias." Berger continued, "We are focused first and foremost on the needs of cancer patients - to have new medicines that provide both safe and effective treatment of their malignancies. Our unwavering commitment to patients has led us to promptly take the steps we have outlined." The Full Research Report on ARIAD Pharmaceuticals Inc. - including full detailed breakdown, analyst ratings and price targets - is available to download free of charge at: [http://www.AnalystsCorner.com/r/full_research_report/161c_ARIA]
Puma Biotechnology, Inc. Research Report
On October 4, 2013, Puma Biotechnology, Inc. (Puma Biotechnology) announced that it initiated a Phase II clinical trial of its lead drug candidate PB272 (neratinib) as a single agent in patients with solid tumors who have an activating HER2 mutation (basket trial). Puma Biotechnology reported that the Phase II basket trial is an open-label, multicenter, multinational study to evaluate the safety and efficacy of PB272 administered daily to patients who have solid tumors with activating HER2 mutations. Alan H. Auerbach, CEO and President, Puma Biotechnology, commented, "It is estimated that approximately 2-10 percent of patients with solid tumors have a HER2 mutation. Preclinical data suggests that neratinib potently inhibits the activity of these cancer-driving mutations, which could translate into clinical benefit for these patients. We are pleased to initiate this basket study in order to further investigate the efficacy of neratinib in these patients with a particular unmet medical need." Auerbach added, "We anticipate that we may get an initial indication on the efficacy of neratinib in these mutation-positive patients by late this year or early next year and that we may be able to expand this trial with additional patients and additional cohorts during that same time period." The Full Research Report on Puma Biotechnology, Inc. - including full detailed breakdown, analyst ratings and price targets - is available to download free of charge at: [http://www.AnalystsCorner.com/r/full_research_report/4d27_PBYI]
Dyax Corp. Research Report
On October 9, 2013, Dyax Corp. (Dyax) announced the pricing of an underwritten public offering of 9.2 million shares of its common stock, offered at a price to the public of $6.50 per share. According to Dyax, gross proceeds from the offering are expected to be $60 million, before deducting the underwriting discount and other estimated offering expenses payable by the Company, and the offering is expected to close on or about October 15, 2013, subject to customary closing conditions. Dyax further reported that it intends to use the net proceeds from this offering to fund research and development activities, including the development of DX-2930, a therapeutic candidate for the prophylactic treatment of hereditary angioedema (HAE), and for general corporate purposes. The Full Research Report on Dyax Corp. - including full detailed breakdown, analyst ratings and price targets - is available to download free of charge at: [http://www.AnalystsCorner.com/r/full_research_report/58ae_DYAX]
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