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      10x Genomics Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Outlook for 2025

      10x Genomics Logo (PRNewsfoto/10x Genomics, Inc.)

      News provided by

      10x Genomics, Inc.

      Feb 12, 2025, 16:05 ET

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      PLEASANTON, Calif., Feb. 12, 2025 /PRNewswire/ -- 10x Genomics, Inc. (Nasdaq: TXG), a leader in single cell and spatial biology, today reported financial results for the fourth quarter and full year ended December 31, 2024 and provided outlook for 2025.

      Recent Updates

      • Revenue was $165.0 million for the fourth quarter and $610.8 million for the full year of 2024, representing 10% and 1% decreases over the corresponding periods of 2023.
      • In collaboration with the Chan Zuckerberg Initiative (CZI) and Ultima Genomics, launched the Billion Cells Project, an effort to generate an unprecedented one billion cell dataset to fuel rapid progress in AI model development in biology.
      • Cash and cash equivalents and marketable securities were $393.4 million as of December 31, 2024, an increase of $4.7 million over prior year.

      "In 2024, we launched major new products across all three of our platforms and we made changes to our commercial organization and go-to-market strategy," said Serge Saxonov, Co-founder and CEO of 10x Genomics. "As we kick off 2025, our goal is to take advantage of these changes and deliver consistent execution. Despite the current uncertainty within U.S. academic research, we continue to have strong conviction in the large opportunity ahead."

      Fourth Quarter 2024 Financial Results

      Revenue was $165.0 million for the three months ended December 31, 2024, a 10% decrease from $184.0 million for the corresponding period. 

      Gross margin was 67% for the fourth quarter of 2024, as compared to 63% for the corresponding prior year period. The increase in gross margin was primarily due to change in product mix.

      Operating expenses were $160.8 million for the fourth quarter of 2024, a 6% decrease from $171.0 million for the corresponding prior year period. The decrease was primarily driven by a $19.6 million in-process research and development expense related to an agreement to acquire certain intangible and other assets in the prior year period, partially offset by an increase in outside litigation expenses.

      Operating loss was $49.8 million for the fourth quarter of 2024, as compared to an operating loss of $55.2 million for the corresponding prior year period. Operating loss includes $32.5 million of stock-based compensation for the fourth quarter of 2024, as compared to $38.9 million for the fourth quarter of 2023.

      Net loss was $49.0 million for the fourth quarter of 2024, as compared to a net loss of $49.0 million for the corresponding prior year period.

      Full Year 2024 Financial Results

      Revenue was $610.8 million for the year ended December 31, 2024, a 1% decrease from $618.7 million for 2023.

      Gross margin was 68% for full year 2024, as compared to 66% for 2023. The increase in gross margin was primarily due to change in product mix.

      Operating expenses were $609.0 million for full year 2024, as compared to $674.6 million for 2023, an decrease of 10%. The decrease was primarily driven by a $61.0 million in-process research and development expense related to an agreement to acquire certain intangible and other assets in the prior year period and lower personnel expenses, including stock-based compensation expense, partially offset by higher outside legal expenses.

      Operating loss was $194.6 million for full year 2024, as compared to an operating loss of $265.3 million for 2023. This includes $140.7 million of stock-based compensation for full year 2024, as compared to $167.0 million for full year 2023.

      Net loss was $182.6 million for full year 2024, as compared to a net loss of $255.1 million for 2023.

      Cash and cash equivalents and marketable securities were $393.4 million as of December 31, 2024.

      2025 Financial Guidance 

      10x Genomics expects full year 2025 revenue to be in the range of $610 million to $630 million, representing 0% to 3% growth over full year 2024. At the midpoint, this guidance implies double-digit growth for both Chromium reactions and overall spatial revenue.

      Webcast and Conference Call Information

      10x Genomics will host a conference call to discuss the fourth quarter and full year 2024 financial results, business developments and outlook after market close on Thursday, February 12, 2025 at 1:30 PM Pacific Time / 4:30 PM Eastern Time. A webcast of the conference call can be accessed at http://investors.10xgenomics.com. The webcast will be archived and available for replay for at least 45 days after the event.

      About 10x Genomics

      10x Genomics is a life science technology company building products to accelerate the mastery of biology and advance human health. Our integrated solutions include instruments, consumables and software for single cell and spatial biology, which help academic and translational researchers and biopharmaceutical companies understand biological systems at a resolution and scale that matches the complexity of biology. Our products are behind breakthroughs in oncology, immunology, neuroscience and more, fueling powerful discoveries that are transforming the world's understanding of health and disease. To learn more, visit 10xgenomics.com or connect with us on LinkedIn, X (Twitter), Facebook, Bluesky or YouTube.

      Forward Looking Statements

      This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 as contained in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are subject to the "safe harbor" created by those sections. All statements included in this press release, other than statements of historical facts, may be forward-looking statements. Forward-looking statements generally can be identified by the use of forward-looking terminology such as "may," "might," "will," "should," "expect," "plan," "anticipate," "could," "intend," "target," "project," "contemplate," "believe," "see," "estimate," "predict," "potential," "would," "likely," "seek" or "continue" or the negatives of these terms or variations of them or similar terminology, but the absence of these words does not mean that a statement is not forward-looking. These forward-looking statements include statements regarding 10x Genomics, Inc.'s collaboration with CZI and Ultima Genomics, positioning, product launches, commercial organization restructuring, go-to-market strategy, goals, uncertainty within academic research, commercial opportunity and our financial performance and results of operations, including our expectations regarding revenue and guidance. These statements are based on management's current expectations, forecasts, beliefs, assumptions and information currently available to management. Actual outcomes and results could differ materially from these statements due to a number of factors and such statements should not be relied upon as representing 10x Genomics, Inc.'s views as of any date subsequent to the date of this press release. 10x Genomics, Inc. disclaims any obligation to update any forward-looking statements provided to reflect any change in our expectations or any change in events, conditions or circumstances on which any such statement is based, except as required by law. The material risks and uncertainties that could affect 10x Genomics, Inc.'s financial and operating results and cause actual results to differ materially from those indicated by the forward-looking statements made in this press release include those discussed under the captions "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" in the company's most recently-filed 10-K and elsewhere in the documents 10x Genomics, Inc. files with the Securities and Exchange Commission from time to time.

      Disclosure Information

      10x Genomics uses filings with the Securities and Exchange Commission, our website (www.10xgenomics.com), press releases, public conference calls, public webcasts and our social media accounts as means of disclosing material non-public information and for complying with our disclosure obligations under Regulation FD.

      Contacts
      Investors: [email protected]
      Media: [email protected] 

      10x Genomics, Inc.

      Consolidated Statement of Operations

      (Unaudited)

      (In thousands, except share and per share data)



      Three Months Ended
      December 31,


      Year Ended
      December 31,


      2024


      2023


      2024


      2023

      Revenue (1)

      $         165,021


      $         183,979


      $         610,785


      $         618,727

      Cost of revenue (2)

      54,066


      68,197


      196,303


      209,414

      Gross profit

      110,955


      115,782


      414,482


      409,313

      Operating expenses:








      Research and development (2)

      66,968


      65,267


      264,698


      270,332

      In-process research and development

      —


      19,578


      —


      60,980

      Selling, general and administrative (2)

      93,826


      86,125


      344,343


      343,330

      Total operating expenses

      160,794


      170,970


      609,041


      674,642

      Loss from operations

      (49,839)


      (55,188)


      (194,559)


      (265,329)

      Other income (expense):








      Interest income

      4,026


      4,637


      18,448


      16,906

      Interest expense

      —


      (8)


      (4)


      (33)

      Other income (expense), net

      (2,567)


      3,961


      (1,585)


      (307)

      Total other income

      1,459


      8,590


      16,859


      16,566

      Loss before provision for income taxes

      (48,380)


      (46,598)


      (177,700)


      (248,763)

      Provision for income taxes

      648


      2,354


      4,927


      6,336

      Net loss

      $          (49,028)


      $          (48,952)


      $       (182,627)


      $       (255,099)









      Net loss per share, basic and diluted

      $              (0.40)


      $              (0.41)


      $              (1.52)


      $              (2.18)

      Weighted-average shares used to compute net loss per share, basic and diluted

      121,596,351


      118,565,724


      120,451,550


      117,165,036



      (1)

      The following table represents revenue by source for the periods indicated (in thousands). Spatial products includes the Company's Visium and Xenium products:



      Three Months Ended
      December 31,


      Year Ended
      December 31,



      2024


      2023


      2024


      2023

      Instruments









      Chromium


      $           10,929


      $           11,150


      $           35,212


      $           47,866

      Spatial


      13,425


      27,248


      57,503


      75,605

      Total instruments revenue


      24,354


      38,398


      92,715


      123,471

      Consumables









      Chromium


      97,737


      118,144


      372,308


      420,316

      Spatial


      35,795


      22,170


      121,124


      59,237

      Total consumables revenue


      133,532


      140,314


      493,432


      479,553

      Services


      7,135


      5,267


      24,638


      15,703

      Total revenue


      $         165,021


      $         183,979


      $         610,785


      $         618,727

      The following table presents revenue by geography based on the location of the customer for the periods indicated (in thousands):




      Three Months Ended
      December 31,


      Year Ended
      December 31,



      2024


      2023


      2024


      2023

      Americas









      United States


      $           84,285


      $           99,322


      $         334,318


      $         360,091

      Americas (excluding United States)


      2,936


      4,520


      13,447


      13,101

      Total Americas


      87,221


      103,842


      347,765


      373,192

      Europe, Middle East and Africa


      49,828


      50,589


      159,762


      142,276

      Asia-Pacific









      China


      14,609


      11,748


      57,300


      50,965

      Asia-Pacific (excluding China)


      13,363


      17,800


      45,958


      52,294

      Total Asia-Pacific


      27,972


      29,548


      103,258


      103,259

      Total Revenue


      $         165,021


      $         183,979


      $         610,785


      $         618,727

      (2)

      Includes stock-based compensation expense as follows:




      Three Months Ended
      December 31,


      Year Ended
      December 31,

      (in thousands)

      2024


      2023


      2024


      2023

      Cost of revenue

      $           2,221


      $           1,928


      $           8,348


      $           7,068

      Research and development

      15,587


      17,608


      66,315


      72,804

      Selling, general and administrative

      14,731


      19,382


      66,086


      87,078

      Total stock-based compensation expense

      $         32,539


      $         38,918


      $       140,749


      $       166,950

      10x Genomics, Inc.

      Consolidated Balance Sheets

      (In thousands, except share and per share data)



      December 31,


      2024


      2023

      Assets




      Current assets:




      Cash and cash equivalents

      $         344,067


      $         359,284

      Marketable securities

      49,335


      29,411

      Accounts receivable, net

      87,862


      114,832

      Inventory

      83,107


      73,706

      Prepaid expenses and other current assets

      20,016


      18,789

      Total current assets

      584,387


      596,022

      Property and equipment, net

      252,648


      279,571

      Operating lease right-of-use assets

      57,290


      65,361

      Goodwill

      4,511


      4,511

      Intangible assets, net

      15,671


      16,616

      Other noncurrent assets

      4,129


      3,062

      Total assets

      $         918,636


      $         965,143

      Liabilities and stockholders' equity




      Current liabilities:




      Accounts payable

      $           12,909


      $           15,738

      Accrued compensation and related benefits

      33,615


      30,105

      Accrued expenses and other current liabilities

      41,165


      56,648

      Deferred revenue

      20,658


      13,150

      Operating lease liabilities

      9,286


      11,521

      Total current liabilities

      117,633


      127,162

      Operating lease liabilities, noncurrent

      73,327


      83,849

      Deferred revenue, noncurrent

      12,513


      8,814

      Other noncurrent liabilities

      5,029


      4,275

      Total liabilities

      208,502


      224,100

      Commitments and contingencies




      Stockholders' equity:




      Preferred stock, $0.00001 par value; 100,000,000 shares authorized, no shares issued or
      outstanding as of December 31, 2024 and December 31, 2023

      —


      —

      Common stock, $0.00001 par value; 1,100,000,000 shares authorized and 122,291,837
      and 119,095,362 shares issued and outstanding as of December 31, 2024 and 2023

      2


      2

      Additional paid-in capital

      2,177,672


      2,025,890

      Accumulated deficit

      (1,467,047)


      (1,284,420)

      Accumulated other comprehensive loss

      (493)


      (429)

      Total stockholders' equity

      710,134


      741,043

      Total liabilities and stockholders' equity

      $         918,636


      $         965,143

      Cumulative instruments sold



      As of December 31,


      2024


      2023


      2022

      Chromium


      5,808


      5,180


      4,411

      Visium CytAssist


      810


      531


      211

      Xenium


      421


      255


      8

      Cumulative instruments sold


      7,039


      5,966


      4,630


      Total consumables reactions sold



      Year ended December 31,


      2024


      2023


      2022

      Chromium


      310,900


      312,500


      290,900

      Visium


      35,400


      29,300


      28,300

      Xenium


      10,800


      5,200


      100

      Total consumable reactions


      357,100


      347,000


      319,300

      SOURCE 10x Genomics, Inc.

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