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      Alexandria Real Estate Equities, Inc., at the Vanguard of the Life Science Industry, Providing High-Quality Office/Laboratory Space to Meet Historic-High Demand, Reports: 4Q21 and 2021 Net Income per Share - Diluted of $0.47 and $3.82, respectively; 4Q21 and 2021 FFO per Share - Diluted, As Adjusted, of $1.97 and $7.76, respectively


      News provided by

      Alexandria Real Estate Equities, Inc.

      Jan 31, 2022, 16:10 ET

      Share this article

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      PASADENA, Calif., Jan. 31, 2022 /PRNewswire/ -- Alexandria Real Estate Equities, Inc. (NYSE:ARE) announced financial and operating results for the fourth quarter and year ended December 31, 2021.

      Continue Reading
      2021q4_1
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      2021q4_10
      2021q4_10
      2021q4_11
      2021q4_11
      2021q4_12
      2021q4_12

      Key highlights







      Operating results

      4Q21


      4Q20


      2021


      2020


      Total revenues:









      In millions

      $  576.9


      $     463.7


      $  2,114.2


      $  1,885.6


      Growth

      24.4%



      12.1%



      Net income attributable to Alexandria's common stockholders – diluted

      In millions

      $    72.8


      $     435.9


      $     563.4


      $     760.8


      Per share

      $    0.47


      $       3.26


      $       3.82


      $       6.01


      Funds from operations attributable to Alexandria's common stockholders – diluted, as adjusted


      In millions

      $  303.6


      $     246.6


      $  1,144.9


      $     923.8


      Per share

      $    1.97


      $       1.84


      $       7.76


      $       7.30


      Historic leasing volume and rental rate growth

      • Historic demand for our high-quality office/laboratory space has translated into record leasing volume and rental rate growth in 2021 for our overall portfolio and our value-creation pipeline.


      4Q21


      Previous
      Quarterly
      Record


      2021


      Previous
      Annual
      Record

      Total leasing activity – RSF


      4,094,174

      (1)

      1,933,838


      9,516,301

      (1)

      5,062,722

      Leasing of development and redevelopment
         space – RSF


      1,795,633

      (1)

      1,063,951


      3,867,383

      (1)

      2,258,262

      Lease renewals and re-leasing of space:









      RSF (included in total leasing activity above)


      1,947,727

      (1)

      1,472,713


      4,614,040

      (1)

      2,562,178

      Rental rate increases


      35.9%




      37.9%

      (1)

      37.6%

      Rental rate increases (cash basis)


      22.9%




      22.6%

      (1)

      18.3%


      (1)     Represents the highest leasing volume and rental rate growth in Company history.

      Continued strong net operating income and internal growth

      • Net operating income (cash basis) of $1.4 billion for 4Q21 annualized, up $279.9 million, or 24.2%, compared to 4Q20 annualized.
      • 95% of our leases contain contractual annual rent escalations approximating 3%.
      • Same property net operating income growth:
        • 5.0% and 7.5% (cash basis) for 4Q21 over 4Q20.
        • 4.2% and 7.1% (cash basis) for 2021 over 2020.

      A REIT industry-leading high-quality tenant roster with high-quality revenues and cash flows, strong margins, and operational excellence; growth of 100 bps in occupancy over 4Q20(1)

      Percentage of total annual rental revenue in effect from investment-grade or
         publicly traded large cap tenants


      51%



      Occupancy of operating properties in North America


      94.0%



      Occupancy of operating properties in North America (excluding vacancy at
         recently acquired properties)


      98.7%

      (1)


      Operating margin


      70%



      Adjusted EBITDA margin


      71%








      Weighted-average remaining lease term:





      All tenants


      7.5

      years

      Top 20 tenants


      10.9

      years



      (1)

      Excludes 1.8 million RSF, or 4.7%, of vacancy at recently acquired properties representing lease-up opportunities that are expected to provide incremental annual rental revenues. Excluding recently acquired vacancies, occupancy was 98.7% as of December 31, 2021, up 100 bps from 97.7% as of December 31, 2020. Refer to "Occupancy" in our Supplemental Information.

      Historic high demand drives visibility for future growth aggregating $610 million of incremental annual rental revenue from 7.4 million RSF of value-creation projects that are 83% leased/negotiating

      Our highly leased value-creation pipeline of current and near-term projects that are under construction or that will commence construction in the next six quarters is expected to generate greater than $610 million of incremental annual rental revenues, primarily commencing from 1Q22 through 4Q24.

      • 7.4 million RSF of our value-creation projects are either under construction or expected to commence construction in the next six quarters.
      • 83% leased/negotiating.

      Strong and flexible balance sheet with significant liquidity

      • Investment-grade credit ratings ranked in the top 10% among all publicly traded U.S. REITs as of December 31, 2021.
      • Net debt and preferred stock to Adjusted EBITDA of 5.2x and fixed-charge coverage ratio of 5.3x for 4Q21 annualized, representing the best ratios in the past 10 years.
      • Total debt and preferred stock to gross assets of 26% as of December 31, 2021.
      • $5.4 billion liquidity as of December 31, 2021, including our outstanding forward equity sales agreements entered into in January 2022.

      Strategic value harvesting and asset recycling

      During 4Q21, we completed $2.0 billion in dispositions and partial interest sales at an average capitalization rate (cash basis) of 4.2%.

      Continued dividend strategy to share growth in cash flows with stockholders

      Common stock dividend declared for 4Q21 of $1.15 per common share, aggregating $4.48 per common share for the year ended December 31, 2021, up 24 cents, or 6%, over the year ended December 31, 2020. Our FFO payout ratio of 60% for the three months ended December 31, 2021 allows us to continue to share growth in cash flows from operating activities with our stockholders while also retaining a significant portion for reinvestment.

      Key items included in operating results

      Key items included in net income attributable to Alexandria's common stockholders:












      4Q21


      4Q20


      4Q21


      4Q20


      2021


      2020


      2021


      2020

      (In millions, except per share
           amounts)

      Amount


      Per Share –
      Diluted


      Amount


      Per Share –
      Diluted

      Unrealized (losses) gains on
        non-real estate investments

      $ (139.7)


      $ 233.5


      $ (0.91)


      $ 1.75


      $  43.6


      $  374.0


      $  0.30


      $ 2.96

      Significant realized gains on
        non-real estate investments

      —


      —


      —


      —


      110.1


      —


      0.75


      —

      Gain on sales of real estate

      124.2

      (1)

      152.5


      0.80


      1.14


      126.6


      154.1


      0.86


      1.22

      Impairment of real estate

      —


      (25.2)


      —


      (0.19)


      (52.7)


      (55.7)


      (0.35)


      (0.44)

      Impairment of non-real estate
        investments

      —


      —


      —


      —


      —


      (24.5)


      —


      (0.19)

      Loss on early extinguishment
        of debt

      —


      (7.9)


      —


      (0.06)


      (67.3)


      (60.7)


      (0.46)


      (0.48)

      Termination fee

      —


      —


      —


      —


      —


      86.2


      —


      0.68

      Acceleration of stock
        compensation expense due to
        executive officer resignation

      —


      —


      —


      —


      —


      (4.5)


      —


      (0.04)

      Total

      $  (15.5)


      $ 352.9


      $ (0.11)


      $ 2.64


      $  160.3


      $  468.9


      $  1.10


      $ 3.71


      (1)     Refer to "Funds from operations and funds from operations per share" of this Earnings Press Release for additional details.

      External growth and investment in real estate

      Alexandria at the vanguard of innovation for over 850 tenants, with a focus on accommodating current tenant needs and providing a path for their future growth

      • During 4Q21, we completed acquisitions in our key life science cluster submarkets aggregating 4.1 million SF, comprising 3.9 million RSF of future development opportunities and 191,879 RSF of operating space, for an aggregate purchase price of $1.5 billion, including our previously announced acquisition of One Rogers Street in our Cambridge submarket for a purchase price of $849.4 million. These acquisitions are primarily focused on future development or redevelopment opportunities to expand our mega campuses and accommodate the future growth of our tenants.

      Delivery and commencement of value-creation projects

      • During 4Q21, we placed into service development and redevelopment projects aggregating 600,768 RSF that are 100% leased across multiple submarkets.
      • Annual net operating income (cash basis) is expected to increase by $39 million upon the burn-off of initial free rent from recently delivered projects.
      • During 4Q21, we commenced construction on four value-creation projects aggregating 1.1 million RSF, including a 403,892 RSF recently acquired redevelopment project at One Rogers Street, which expands our Alexandria Center® at Kendall Square mega campus in Cambridge. We pre-leased the entire building by executing leases aggregating 403,892 RSF prior to the closing of the acquisition in December 2021.
      • In January 2022, we completed the acquisition of 202,997 SF additional development entitlements, for an aggregate of 507,997 SF, at our 421 Park Drive future development site in our Alexandria Center® for Life Science – Fenway mega campus in our Fenway submarket.

      Value-creation pipeline of new Class A development and redevelopment projects as
      a percentage of gross assets


      4Q21

      Under construction projects 82% leased/negotiating


      9%

      Pre-leased/negotiating near-term projects 89% leased/negotiating


      2%

      Income-producing/potential cash flows/covered land play(1)


      6%

      Land


      2%




      (1)

      Includes projects that have existing buildings that are generating or can generate operating cash flows. Also includes development rights associated with existing operating campuses.

      Balance sheet management

      Credit rating outlook improvement

      In October 2021, S&P Global Ratings upgraded our corporate issuer credit rating outlook to BBB+/Positive from BBB+/Stable as a result of our consistently strong operating performance and long-term positive fundamentals.

      Key metrics as of December 31, 2021

      • $44.0 billion of total market capitalization.
      • $35.2 billion of total equity capitalization; represents top 10% in total equity capitalization among all publicly traded U.S. REITs as of December 31, 2021.
      • No debt maturities prior to 2024.
      • 12.1 years weighted-average remaining term of debt as of December 31, 2021.


      4Q21


      Goal



      Quarter


      Trailing


      4Q22



      Annualized


      12 Months


      Annualized

      Net debt and preferred stock to
         Adjusted EBITDA


      5.2x   (1)


      5.6x


      Less than or equal to 5.1x

      Fixed-charge coverage ratio


      5.3x   (1)


      5.0x


      Greater than or equal to 5.1x


      (1)

      Net debt and preferred stock to adjusted EBITDA and fixed-charge coverage represent the best ratios in the past 10 years.

      Key capital events

      • In December 2021, we entered into a new ATM common stock offering program, which allows us to sell up to an aggregate of $1.0 billion of our common stock. As of January 31, 2022, the full amount remains available for future sales of our common stock.
      • In December 2021, we settled the outstanding forward equity sales agreements by issuing 4.6 million shares of common stock and received net proceeds of $770.6 million.
      • In January 2022, we entered into new forward equity sales agreements aggregating $1.7 billion to sell 8.1 million shares of our common stock (including the exercise of underwriters' option) at a public offering price of $210.00 per share, before underwriting discounts and commissions.

      Investments

      • As of December 31, 2021, our investments aggregated $1.9 billion, including unrealized gains of $797.7 million.
      • Investment income of $259.5 million for the year ended December 31, 2021 included $215.8 million in realized gains and $43.6 million in unrealized gains.

      Industry and ESG leadership: catalyzing and leading the way for positive change to benefit human health and society

      • In January 2022, Alexandria Venture Investments, our strategic venture capital platform, was recognized by Silicon Valley Bank in its "Healthcare Investments and Exits: 2022 Annual Report" as the #1 most active corporate investor in biopharma by new deal volume (2020-2021) for the fifth consecutive year. Alexandria's venture activity provides us with, among other things, mission-critical data and knowledge on key industry innovations and trends.
      • In December 2021, Alexandria established a new social responsibility pillar to address America's growing mental health crisis, with a focus on helping children cope with the loss of a parent or family member to suicide. By partnering with Camp Kita, a tuition-free summer camp for 8- to 17-year-olds who are impacted by the loss of a family member to suicide, we have enabled the non-profit to have long-term access to 28 acres in Acton, Maine that will serve as the camp's future home. The dedicated space will allow Camp Kita to expand its programming, advance its mission, and support the mental health of a community of young survivors.
      • As a testament to Alexandria's operational excellence and exceptional team, in November 2021, we were recognized at the 2021 BOMA Boston TOBY (The Outstanding Building of the Year) & Industry Awards for the Laboratory Building of the Year (100 Binney Street) and the Corporate Facility of the Year (200 Technology Square). Five members from our Greater Boston team were also honored for their individual achievements. The TOBY & Industry Awards recognize excellence in property management, building operations, and service in the commercial real estate industry.
      • In November 2021, Alexandria's executive chairman and founder, Joel S. Marcus, joined the National Medal of Honor Museum Foundation at the Dallas Cowboys' "Salute to Service" game to support the future National Medal of Honor Museum in Arlington, Texas and its mission to inspire visitors with the stories of our country's Medal of Honor recipients for generations to come. Mr. Marcus has served on the foundation's board of directors since 2019.
      • In October 2021, OneFifteen, an innovative, data-driven non-profit evidence-based healthcare ecosystem dedicated to the full and sustained recovery of people living with addiction, celebrated its second anniversary. Since seeing its first patients in October 2019 at its pioneering campus in Dayton, Ohio, which was designed and developed by Alexandria, OneFifteen has treated over 4,000 patients and conducted over 11,500 telehealth visits.
      • In October 2021, STEAM:Coders honored Alexandria with the Corporate Vanguard Award, recognizing our longstanding commitment to the non-profit's mission to inspire underrepresented and underserved students and their families through science, technology, engineering, art, and math (STEAM) education in preparation for academic and career opportunities.

      Acquisitions
      December 31, 2021
      (Dollars in thousands)











      Square Footage














      Acquisitions With Development/Redevelopment Opportunities(1)








      Property


      Submarket/Market


      Date of

      Purchase


      Number of
      Properties


      Operating

      Occupancy


      Future
      Development


      Active
      Development/
      Redevelopment


      Operating With
      Future
      Development/
      Redevelopment


      Operating(2)


      Operating


      Total(3)


      Purchase Price


      Completed in YTD 3Q21






      76


      93%


      7,946,121


      1,434,803


      2,823,087


      2,801,041


      238,948


      14,272,878


      $

      3,941,902



























      Completed in 4Q21:

























      One Rogers Street


      Cambridge/Inner Suburbs/
         
      Greater Boston


      12/30/21


      1


      100   (4)


      TBD


      403,892


      —


      4,367


      —


      408,259



      849,422


      1178 El Camino Real


      South San Francisco/
         San Francisco Bay Area


      11/5/21


      —


      N/A


      620,000


      —


      —


      —


      —


      620,000



      128,000


      3420 and 3440 Hillview
         Avenue


      Greater Stanford/San 
         Francisco Bay Area


      10/5/21


      2


      75


      —


      —


      185,228


      —


      —


      185,228



      203,800


      888 Bransten Road


      Greater Stanford/San
         Francisco Bay Area


      11/4/21


      —


      N/A


      210,830


      —


      —


      —


      —


      210,830



      55,000


      Other


      Various


      Various


      8


      75


      1,888,874


      144,113


      489,466


      —


      187,512


      2,709,965



      291,030








      11


      75


      2,719,704


      548,005


      674,694

      (5)

      4,367

      (5)

      187,512

      (5)

      4,134,282



      1,527,252


      2021 acquisitions






      87


      91%


      10,665,825


      1,982,808


      3,497,781


      2,805,408


      426,460


      18,407,160


      $

      5,469,154



























      (1)

      We expect to provide total estimated costs and related yields for development and redevelopment projects in the future, subsequent to the commencement of construction. Refer to "New Class A development and redevelopment properties: current projects" in our Supplemental Information for additional details on active development and redevelopment projects.

      (2)

      Represents the operating component of our value-creation acquisitions that is not expected to undergo development or redevelopment.

      (3)

      Represents total square footage upon completion of development or redevelopment of a new Class A property. Square footage presented includes RSF of buildings currently in operations with future development or redevelopment opportunities. We intend to demolish and develop or to redevelop the existing properties upon expiration of the existing in-place leases. Refer to "Definitions and reconciliations" in our Supplemental Information for additional details on value-creation square feet currently included in rental properties.

      (4)

      We pre-leased the entire building by executing leases aggregating 403,892 RSF prior to closing of the acquisition in December 2021.

      (5)

      We expect the acquisitions completed during the three months ended December 31, 2021 to generate initial annual net operating income of $14.8 million for the twelve months following acquisition. These acquisitions included 11 operating properties with a weighted-average acquisition date of October 19, 2021 (weighted by initial annual net operating income).

      Acquisitions (continued)
      December 31, 2021
      (Dollars in thousands)











      Square Footage














      Acquisitions With Development/Redevelopment Opportunities(1)








      Property


      Submarket/Market


      Date of

      Purchase


      Number of
      Properties


      Operating

      Occupancy


      Future
      Development


      Active
      Development/
      Redevelopment


      Operating With
      Future
      Development/
      Redevelopment


      Operating(2)


      Operating


      Total(3)


      Purchase
      Price


      Completed in January 2022:

























      421 Park Drive(4)


      Fenway/Greater Boston


      1/13/22


      —


      N/A


      202,997

      (4)

      —


      —


      —


      —


      202,997


      $

      81,119


      225 and 235 Presidential Way


      Route 128/Greater Boston


      1/28/22


      2


      100%


      —


      —


      440,130


      —


      —


      440,130



      124,673


      3301, 3303, 3305, and 3307 Hillview
         Avenue


      Greater Stanford/
         
      San Francisco Bay Area


      1/6/22


      4


      100


      —


      —


      292,013


      —


      —


      292,013



      446,000


      Costa Verde by Alexandria


      University Town Center/

         San Diego


      1/11/22


      1


      100


      537,000


      —


      8,730


      —


      —


      545,730



      125,000


      Alexandria Center® for Life Science –
         Durham


      Research Triangle/Research
         Triangle


      1/11/22


      —


      N/A


      1,175,000


      —


      —


      —


      —


      1,175,000



      99,428


      104 and 108/110/112/114 TW
         Alexander Drive, 2752 East NC
         Highway 54, and 10 South Triangle
         Drive(5)


      Research Triangle/Research
         Triangle


      1/6/22


      4


      88


      750,000


      —


      69,484


      —


      —


      819,484



      80,000


      Other


      Various


      Various


      7


      92


      228,250


      —


      428,097


      381,760


      —


      1,038,107



      263,620








      18


      96%


      2,893,247


      —


      1,238,454


      381,760


      —


      4,513,461



      1,219,840


      Pending acquisitions:

























      Mercer Mega Block


      Lake Union/Seattle


      February
      2022


      —


      N/A


      800,000


      —


      —


      —


      —


      800,000



      143,500


      Intersection Campus


      Texas


      February
      2022


      9


      81%


      —


      —


      998,304


      —


      —


      998,304



      402,000


























      545,500


      Other targeted acquisitions(6)
























      1,234,660


      2022 acquisitions (midpoint)























      $

      3,000,000




























      2022 guidance range





















      $2,500,000 – $3,500,000




























      (1)

      We expect to provide total estimated costs and related yields for development and redevelopment projects in the future, subsequent to the commencement of construction.

      (2)

      Represents the operating component of our value-creation acquisitions that is not expected to undergo development or redevelopment.

      (3)

      Represents total square footage upon completion of development or redevelopment of a new Class A property. Square footage presented includes RSF of buildings currently in operation with future development or redevelopment opportunities. We intend to demolish and develop or to redevelop the existing properties upon expiration of the existing in-place leases. Refer to "Definitions and reconciliations" in our Supplemental Information for additional details on value-creation square feet currently included in rental properties.

      (4)

      Represents the incremental purchase price related to the achievement of additional entitlement rights of 202,997 SF at our Alexandria Center® for Life Science – Fenway mega campus.

      (5)

      Represents the acquisition of fee simple interests in the land underlying our recently acquired 108/110/112/114 TW Alexander Drive buildings, which were previously subject to ground leases.

      (6)

      Includes a land parcel aggregating 680,000 RSF of future development opportunity at 1150 El Camino Real in our South San Francisco submarket. The property is a transit-oriented opportunity with a BART station located on premises that will combine with other contiguous land that was recently acquired, including 1122 and 1178 El Camino Real, to create a new mega campus consisting of 2.0 million RSF of future development opportunities.

      Dispositions and Sales of Partial Interest
      December 31, 2021
      (Dollars in thousands)

      Property


      Submarket/Market


      Date of
      Sale


      Interest
      Sold


      RSF


      Capitalization    
      Rate    


      Capitalization   
      Rate   

      (Cash Basis)   


      Sales Price(1)


      Sales Price
      per RSF


      Gain or
      Consideration
      in Excess of
      Book Value


























      Completed in YTD 3Q21









      1,011,263








      $                       663,283




      $     201,490





























      Completed in 4Q21:


























      50 and 60 Binney Street


      Cambridge/Inner Suburbs/
         
      Greater Boston


      12/15/21


      66%



      532,395


      4.3%



      3.9%



      782,259


      $       2,226


      457,529

      (3)




























      409 and 499 Illinois Street


      Mission Bay/San Francisco Bay Area


      10/5/21


      35%

      (2)


      455,069


      5.0%



      4.2%



      274,681


      $       1,366


      113,756

      (3)


      1500 Owens Street


      Mission Bay/San Francisco Bay Area



      25.1%

      (2)


      158,267

































      455 Mission Bay Boulevard
         South


      Mission Bay/San Francisco Bay Area


      12/16/21


      75%



      228,140


      4.1%



      3.8%



      381,355


      $       1,295


      221,868

      (3)


      1700 Owens Street


      Mission Bay/San Francisco Bay Area





      164,513



































      Menlo Gateway


      Greater Stanford/San Francisco Bay
         Area


      12/21/21


      (4)



      772,983


      5.4%



      5.1%



      397,851

      (5)

      $       1,430


      101,050

      (6)


      2301 5th Avenue


      Lake Union/Seattle


      12/22/21


      100%



      197,135


      6.3%



      4.9%



      118,707


      $          602


      23,175

      (6)


      Other


      Various


      Various


      100%



      79,007


      N/A



      N/A



      12,000


      N/A


      —












      2,587,509








      1,966,853




      917,378



      2021 dispositions and sales of partial interest







      3,598,772








      $                    2,630,136

      (7)



      $  1,118,868

      (8)




























      (1)

      For sales of partial interests; represents the contractual sales price for the percentage interest of the property sold by us.

      (2)

      We recapitalized these consolidated real estate joint ventures and sold: (i) a 35% interest in 409 and 499 Illinois Street and (ii) a 25.1% interest in 1500 Owens Street, resulting in an acquisition by the investor of a 75% ownership interest in each joint venture, including the interest held by our previous joint venture partners.

      (3)

      For each partial interest sale, we retained control over the newly formed real estate joint venture and therefore continued to consolidate this property. We accounted for the difference between the consideration received and the book value of the interest sold as an equity transaction, with no gain or loss recognized in earnings.

      (4)

      We sold our 49.0% interest in Menlo Gateway, which represents our entire equity interest in the unconsolidated real estate joint venture.

      (5)

      Represents a sales price of $541.5 million less our share of the debt held by the unconsolidated real estate joint venture assumed by the buyer aggregating $143.6 million.

      (6)

      We sold our entire interest in this property and recognized the related gain in earnings, classified within gain (loss) on sales of real estate in our consolidated statements of operations.

      (7)

      Represents the highest total volume of dispositions in Company history, at a weighted-average capitalization rate (cash basis) of 4.1%.

      (8)

      We achieved a weighted-average value-creation margin of 75% on our completed dispositions and sales of partial interest.

      Dispositions and Sales of Partial Interest (continued)
      December 31, 2021
      (Dollars in thousands)


      Property


      Market


      Date of
      Sale


      Interest
      Sold


      RSF


      Sales Price

















      Partial interest sale


      Greater Boston


      1Q22


      TBD



      TBD


      $         650,000

      –

      $         750,000


      Other real estate dispositions and partial interest sales




      1Q22


      TBD



      TBD


      50,000

      –

      150,000


      Other targeted real estate dispositions and partial interest sales











      600,000

      –

      1,200,000

















      2022 guidance range











      $      1,300,000

      –

      $      2,100,000

















      Guidance
      December 31, 2021
      (Dollars in millions, except per share amounts)


      The following guidance is based on our current view of existing market conditions and assumptions for the year ending December 31, 2022. There can be no assurance that actual amounts will not be materially higher or lower than these expectations. Also, refer to our discussion of "forward-looking statements" on page 9 of this Earnings Press Release for additional details.


      Projected 2022 Earnings per Share and Funds From Operations per Share Attributable to
         Alexandria's Common Stockholders – Diluted

      Earnings per share(1)


      $2.65 to $2.85

      Depreciation and amortization of real estate assets


      5.65

      Allocation to unvested restricted stock awards


      (0.04)

      Funds from operations per share(2)


      $8.26 to $8.46

      Midpoint


      $8.36







      Key Assumptions


      Low


      High


      Occupancy percentage in North America as of December 31, 2022


      95.2%


      95.8%


      Lease renewals and re-leasing of space:






      Rental rate increases


      30.0%


      35.0%


      Rental rate increases (cash basis)


      18.0%


      23.0%


      Same property performance:






      Net operating income increase


      5.5%


      7.5%


      Net operating income increase (cash basis)


      6.5%


      8.5%


      Straight-line rent revenue


      $            150


      $            160


      General and administrative expenses


      $            168


      $            176


      Capitalization of interest


      $            269


      $            279


      Interest expense


      $              90


      $            100














      Key Credit Metrics


      2022 Guidance

      Net debt and preferred stock to Adjusted EBITDA – 4Q22 annualized


      Less than or equal to 5.1x

      Fixed-charge coverage ratio – 4Q22 annualized


      Greater than or equal to 5.1x




      Key Sources and Uses of Capital


      Range


      Midpoint


      Certain

      Completed
      Items

      Sources of capital:











      Net cash provided by operating activities after
         dividends


      $    275


      $    325


      $

      300




      Incremental debt


      1,375


      1,025



      1,200



      Real estate dispositions and partial interest sales
         (refer to page 7)


      1,300


      2,100



      1,700




      Common equity


      2,250


      3,250



      2,750


      $  1,691


      Total sources of capital


      $ 5,200


      $ 6,700


      $

      5,950




      Uses of capital:











      Construction


      $ 2,700


      $ 3,200


      $

      2,950




      Acquisitions (refer to page 5)


      2,500


      3,500



      3,000


      $  1,220


      Total uses of capital


      $ 5,200


      $ 6,700


      $

      5,950




      Incremental debt (included above):











      Issuance of unsecured senior notes payable


      $ 1,200


      $ 1,700


      $

      1,450




      Unsecured senior line of credit, commercial paper,
         and other


      175


      (675)



      (250)




      Incremental debt


      $ 1,375


      $ 1,025


      $

      1,200















      (1)

      Excludes unrealized gains or losses after December 31, 2021 that are required to be recognized in earnings and are excluded from funds from operations per share, as adjusted.

      (2)

      Refer to "Funds from operations and funds from operations, as adjusted, attributable to Alexandria's common stockholders" in the "Definitions and reconciliations" of our Supplemental Information for additional details.



      Earnings Call Information and About the Company
      December 31, 2021

      We will host a conference call on Tuesday, February 1, 2022, at 3:00 p.m. Eastern Time ("ET")/noon Pacific Time ("PT"), which is open to the general public, to discuss our financial and operating results for the fourth quarter and year ended December 31, 2021. To participate in this conference call, dial (833) 366-1125 or (412) 902-6738 shortly before 3:00 p.m. ET/noon PT and ask the operator to join the call for Alexandria Real Estate Equities, Inc. The audio webcast can be accessed at www.are.com in the "For Investors" section. A replay of the call will be available for a limited time from 5:00 p.m. ET/2:00 p.m. PT on Tuesday, February 1, 2022. The replay number is (877) 344-7529 or (412) 317-0088, and the access code is 10161869.

      Additionally, a copy of this Earnings Press Release and Supplemental Information for the fourth quarter and year ended December 31, 2021, is available in the "For Investors" section of our website at www.are.com or by following this link: http://www.are.com/fs/2021q4.pdf.

      For any questions, please contact Joel S. Marcus, executive chairman and founder; Stephen A. Richardson, co-chief executive officer; Peter M. Moglia, co-chief executive officer and co-chief investment officer; Dean A. Shigenaga, president and chief financial officer; Paula Schwartz, managing director of Rx Communications Group, at (917) 322-2216; or Sara M. Kabakoff, vice president – communications, at (626) 578-0777.

      About the Company

      Alexandria Real Estate Equities, Inc. (NYSE:ARE), an S&P 500® urban office real estate investment trust ("REIT"), is the first, longest-tenured, and pioneering owner, operator, and developer uniquely focused on collaborative life science, agtech, and technology campuses in AAA innovation cluster locations, with a total market capitalization of $44.0 billion as of December 31, 2021, and an asset base in North America of 67.0 million square feet ("SF"). The asset base in North America includes 38.8 million RSF of operating properties and 4.8 million RSF of Class A properties undergoing construction, 8.7 million RSF of near-term and intermediate-term development and redevelopment projects, and 14.7 million SF of future development projects. Founded in 1994, Alexandria pioneered this niche and has since established a significant market presence in key locations, including Greater Boston, the San Francisco Bay Area, New York City, San Diego, Seattle, Maryland, and Research Triangle. Alexandria has a longstanding and proven track record of developing Class A properties clustered in urban life science, agtech, and technology campuses that provide our innovative tenants with highly dynamic and collaborative environments that enhance their ability to successfully recruit and retain world-class talent and inspire productivity, efficiency, creativity, and success. Alexandria also provides strategic capital to transformative life science, agtech, and technology companies through our venture capital platform. We believe our unique business model and diligent underwriting ensure a high-quality and diverse tenant base that results in higher occupancy levels, longer lease terms, higher rental income, higher returns, and greater long-term asset value. For additional information on Alexandria, please visit www.are.com.

      ***********

      This document includes "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Such forward-looking statements include, without limitation, statements regarding our 2022 earnings per share attributable to Alexandria's common stockholders – diluted, 2022 funds from operations per share attributable to Alexandria's common stockholders – diluted, net operating income, and our projected sources and uses of capital. You can identify the forward-looking statements by their use of forward-looking words, such as "forecast," "guidance," "goals," "projects," "estimates," "anticipates," "believes," "expects," "intends," "may," "plans," "seeks," "should," "targets," or "will," or the negative of those words or similar words. These forward-looking statements are based on our current expectations, beliefs, projections, future plans and strategies, anticipated events or trends, and similar expressions concerning matters that are not historical facts, as well as a number of assumptions concerning future events. There can be no assurance that actual results will not be materially higher or lower than these expectations. These statements are subject to risks, uncertainties, assumptions, and other important factors that could cause actual results to differ materially from the results discussed in the forward-looking statements. Factors that might cause such a difference include, without limitation, our failure to obtain capital (debt, construction financing, and/or equity) or refinance debt maturities, lower than expected yields, increased interest rates and operating costs, adverse economic or real estate developments in our markets, our failure to successfully place into service and lease any properties undergoing development or redevelopment and our existing space held for future development or redevelopment (including new properties acquired for that purpose), our failure to successfully operate or lease acquired properties, decreased rental rates, increased vacancy rates or failure to renew or replace expiring leases, defaults on or non-renewal of leases by tenants, adverse general and local economic conditions, an unfavorable capital market environment, decreased leasing activity or lease renewals, failure to obtain LEED and other healthy building certifications and efficiencies, and other risks and uncertainties detailed in our filings with the Securities and Exchange Commission ("SEC"). Accordingly, you are cautioned not to place undue reliance on such forward-looking statements. All forward-looking statements are made as of the date of this Earnings Press Release and Supplemental Information, and unless otherwise stated, we assume no obligation to update this information and expressly disclaim any obligation to update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise. For more discussion relating to risks and uncertainties that could cause actual results to differ materially from those anticipated in our forward-looking statements, and risks to our business in general, please refer to our SEC filings, including our most recent annual report on Form 10-K and any subsequent quarterly reports on Form 10-Q.

      Alexandria®, Lighthouse Design® logo, Building the Future of Life-Changing Innovation™, That's What's in Our DNA®, Labspace®, Alexandria Center®, Alexandria Technology Square®, Alexandria Technology Center®, and Alexandria Innovation Center® are copyrights and trademarks of Alexandria Real Estate Equities, Inc. All other company names, trademarks, and logos referenced herein are the property of their respective owners.

      Consolidated Statements of Operations
      December 31, 2021
      (Dollars in thousands, except per share amounts)



      Three Months Ended


      Year Ended



      12/31/21


      9/30/21


      6/30/21


      3/31/21


      12/31/20


      12/31/21


      12/31/20

      Revenues:















      Income from rentals


      $       574,656


      $       546,527


      $       508,371


      $       478,695


      $       461,335


      $    2,108,249


      $    1,878,208

      Other income


      2,267


      1,232


      1,248


      1,154


      2,385


      5,901


      7,429

      Total revenues


      576,923


      547,759


      509,619


      479,849


      463,720


      2,114,150


      1,885,637
















      Expenses:















      Rental operations


      175,717


      165,995


      143,955


      137,888


      136,767


      623,555


      530,224

      General and administrative


      41,654


      37,931


      37,880


      33,996


      32,690


      151,461


      133,341

      Interest


      34,862


      35,678


      35,158


      36,467


      37,538


      142,165


      171,609

      Depreciation and amortization


      239,254


      210,842


      190,052


      180,913


      177,750


      821,061


      698,104

      Impairment of real estate


      —


      42,620


      4,926


      5,129


      25,177


      52,675


      48,078

      Loss on early extinguishment of debt


      —


      —


      —


      67,253


      7,898


      67,253


      60,668

      Total expenses


      491,487


      493,066


      411,971


      461,646


      417,820


      1,858,170


      1,642,024
















      Equity in earnings of unconsolidated real estate joint ventures


      3,018


      3,091


      2,609


      3,537


      3,593


      12,255


      8,148

      Investment (loss) income


      (112,884)


      67,084


      304,263


      1,014


      255,137


      259,477


      421,321

      Gain (loss) on sales of real estate


      124,226

      (1)

      (435)


      —


      2,779


      152,503


      126,570

      (1)

      154,089

      Net income


      99,796


      124,433


      404,520


      25,533


      457,133


      654,282


      827,171

      Net income attributable to noncontrolling interests


      (24,901)


      (21,286)


      (19,436)


      (17,412)


      (15,649)


      (83,035)


      (56,212)

      Net income attributable to Alexandria Real Estate Equities, Inc.'s
         stockholders


      74,895


      103,147


      385,084


      8,121


      441,484


      571,247


      770,959

      Net income attributable to unvested restricted stock awards


      (2,098)


      (1,883)


      (4,521)


      (2,014)


      (5,561)


      (7,848)


      (10,168)

      Net income attributable to Alexandria Real Estate Equities, Inc.'s common
         stockholders


      $         72,797


      $       101,264


      $       380,563


      $           6,107


      $       435,923


      $       563,399


      $       760,791
















      Net income per share attributable to Alexandria Real Estate Equities, Inc.'s
         common stockholders:















      Basic


      $             0.47


      $             0.67


      $             2.61


      $             0.04


      $             3.26


      $             3.83


      $             6.03

      Diluted


      $             0.47


      $             0.67


      $             2.61


      $             0.04


      $             3.26


      $             3.82


      $             6.01
















      Weighted-average shares of common stock outstanding:















      Basic


      153,464


      150,854


      145,825


      137,319


      133,688


      146,921


      126,106

      Diluted


      154,307


      151,561


      146,058


      137,688


      133,827


      147,460


      126,490
















      Dividends declared per share of common stock


      $             1.15


      $             1.12


      $             1.12


      $             1.09


      $             1.09


      $             4.48


      $             4.24



      (1)

      Refer to "Funds from operations and funds from operations per share" of this Earnings Press Release for additional details.

      Consolidated Balance Sheets
      December 31, 2021
      (In thousands)



      12/31/21


      9/30/21


      6/30/21


      3/31/21


      12/31/20

      Assets











      Investments in real estate


      $  24,980,669


      $  23,071,514


      $  21,692,385


      $  20,253,418


      $  18,092,372

      Investments in unconsolidated real estate joint ventures


      38,483


      321,737


      323,622


      325,928


      332,349

      Cash and cash equivalents


      361,348


      325,872


      323,876


      492,184


      568,532

      Restricted cash


      53,879


      42,182


      33,697


      42,219


      29,173

      Tenant receivables


      7,379


      7,749


      6,710


      7,556


      7,333

      Deferred rent


      839,335


      816,219


      781,600


      751,967


      722,751

      Deferred leasing costs


      402,898


      329,952


      321,005


      294,328


      272,673

      Investments


      1,876,564


      2,046,878


      1,999,283


      1,641,811


      1,611,114

      Other assets


      1,658,818


      1,596,615


      1,536,672


      1,424,935


      1,191,581

      Total assets


      $  30,219,373


      $  28,558,718


      $  27,018,850


      $  25,234,346


      $  22,827,878












      Liabilities, Noncontrolling Interests, and Equity











      Secured notes payable


      $       205,198


      $       198,758


      $       227,984


      $       229,406


      $       230,925

      Unsecured senior notes payable


      8,316,678


      8,314,851


      8,313,025


      8,311,512


      7,232,370

      Unsecured senior line of credit and commercial paper


      269,990


      749,978


      299,990


      —


      99,991

      Accounts payable, accrued expenses, and other liabilities


      2,210,410


      2,149,450


      1,825,387


      1,750,687


      1,669,832

      Dividends payable


      183,847


      173,560


      170,647


      160,779


      150,982

      Total liabilities


      11,186,123


      11,586,597


      10,837,033


      10,452,384


      9,384,100












      Commitments and contingencies






















      Redeemable noncontrolling interests


      9,612


      11,681


      11,567


      11,454


      11,342












      Alexandria Real Estate Equities, Inc.'s stockholders' equity:











      Common stock


      1,580


      1,532


      1,507


      1,457


      1,367

      Additional paid-in capital


      16,195,256


      14,727,735


      14,194,023


      12,994,748


      11,730,970

      Accumulated other comprehensive loss


      (7,294)


      (6,029)


      (4,508)


      (5,799)


      (6,625)

      Alexandria Real Estate Equities, Inc.'s stockholders' equity


      16,189,542


      14,723,238


      14,191,022


      12,990,406


      11,725,712

      Noncontrolling interests


      2,834,096


      2,237,202


      1,979,228


      1,780,102


      1,706,724

      Total equity


      19,023,638


      16,960,440


      16,170,250


      14,770,508


      13,432,436

      Total liabilities, noncontrolling interests, and equity


      $  30,219,373


      $  28,558,718


      $  27,018,850


      $  25,234,346


      $  22,827,878

      Funds From Operations and Funds From Operations per Share
      December 31, 2021
      (In thousands)


      The following table presents a reconciliation of net income (loss) attributable to Alexandria's common stockholders, the most directly comparable financial measure presented in accordance with U.S. generally accepted accounting principles ("GAAP"), including our share of amounts from consolidated and unconsolidated real estate joint ventures, to funds from operations attributable to Alexandria's common stockholders – diluted, and funds from operations attributable to Alexandria's common stockholders – diluted, as adjusted, for the periods below:




      Three Months Ended


      Year Ended



      12/31/21


      9/30/21


      6/30/21


      3/31/21


      12/31/20


      12/31/21


      12/31/20

      Net income attributable to Alexandria's common stockholders


      $     72,797


      $   101,264


      $   380,563


      $       6,107


      $   435,923


      $   563,399


      $   760,791

      Depreciation and amortization of real estate assets


      234,979


      205,436


      186,498


      177,720


      173,392


      804,633


      684,682

      Noncontrolling share of depreciation and amortization from consolidated real
         estate JVs


      (21,265)


      (17,871)


      (16,301)


      (15,443)


      (15,032)


      (70,880)


      (61,933)

      Our share of depreciation and amortization from unconsolidated real estate JVs


      3,058


      3,465


      4,135


      3,076


      2,976


      13,734


      11,413

      (Gain) loss on sales of real estate


      (124,226)

      (1)

      435


      —


      (2,779)


      (152,503)


      (126,570)

      (1)

      (154,089)

      Impairment of real estate – rental properties


      —


      18,602


      1,754


      5,129


      25,177


      25,485


      40,501

      Allocation to unvested restricted stock awards


      —


      (1,472)


      (2,191)


      (201)


      (420)


      (6,315)


      (7,018)

      Funds from operations attributable to Alexandria's common stockholders – 
         diluted(2)


      165,343


      309,859


      554,458


      173,609


      469,513


      1,203,486


      1,274,347

      Unrealized losses (gains) on non-real estate investments


      139,716


      14,432


      (244,031)


      46,251


      (233,538)


      (43,632)


      (374,033)

      Significant realized gains on non-real estate investments


      —


      (52,427)


      (34,773)


      (22,919)


      —


      (110,119)


      —

      Impairment of non-real estate investments


      —


      —


      —


      —


      —


      —


      24,482

      Impairment of real estate


      —


      24,018


      3,172


      —


      —


      27,190


      15,221

      Loss on early extinguishment of debt


      —


      —


      —


      67,253


      7,898


      67,253


      60,668

      Termination fee


      —


      —


      —


      —


      —


      —


      (86,179)

      Acceleration of stock compensation expense due to executive officer resignation


      —


      —


      —


      —


      —


      —


      4,499

      Allocation to unvested restricted stock awards


      (1,432)


      149


      3,428


      (1,208)


      2,774


      710


      4,790

      Funds from operations attributable to Alexandria's common stockholders – 
         diluted, as adjusted


      $   303,627


      $   296,031


      $   282,254


      $   262,986


      $   246,647


      $  1,144,888


      $   923,795



      (1)

      Includes $101.1 million related to the sale of our entire 49.0% interest in the unconsolidated real estate joint venture at Menlo Gateway.

      (2)

      Calculated in accordance with standards established by the Nareit Board of Governors.

      Funds From Operations and Funds From Operations per Share (continued)
      December 31, 2021
      (In thousands, except per share amounts)


      The following table presents a reconciliation of net income (loss) per share attributable to Alexandria's common stockholders, the most directly comparable financial measure presented in accordance with GAAP, including our share of amounts from consolidated and unconsolidated real estate joint ventures, to funds from operations per share attributable to Alexandria's common stockholders – diluted, and funds from operations per share attributable to Alexandria's common stockholders – diluted, as adjusted, for the periods below. Per share amounts may not add due to rounding.




      Three Months Ended


      Year Ended



      12/31/21


      9/30/21


      6/30/21


      3/31/21


      12/31/20


      12/31/21


      12/31/20

      Net income per share attributable to Alexandria's common stockholders –
         diluted


      $         0.47


      $         0.67


      $         2.61


      $         0.04


      $         3.26


      $         3.82


      $         6.01

      Depreciation and amortization of real estate assets


      1.40


      1.26


      1.19


      1.20


      1.21


      5.07


      5.01

      (Gain) loss on sales of real estate


      (0.80)


      —


      —


      (0.02)


      (1.14)


      (0.86)


      (1.22)

      Impairment of real estate – rental properties


      —


      0.12


      0.01


      0.04


      0.19


      0.17


      0.32

      Allocation to unvested restricted stock awards


      —


      (0.01)


      (0.01)


      —


      (0.01)


      (0.04)


      (0.05)

      Funds from operations per share attributable to Alexandria's common
         stockholders – diluted


      1.07


      2.04


      3.80


      1.26


      3.51


      8.16


      10.07

      Unrealized losses (gains) on non-real estate investments


      0.91


      0.10


      (1.67)


      0.34


      (1.75)


      (0.30)


      (2.96)

      Significant realized gains on non-real estate investments


      —


      (0.35)


      (0.24)


      (0.17)


      —


      (0.75)


      —

      Impairment of non-real estate investments


      —


      —


      —


      —


      —


      —


      0.19

      Impairment of real estate


      —


      0.16


      0.02


      —


      —


      0.18


      0.12

      Loss on early extinguishment of debt


      —


      —


      —


      0.49


      0.06


      0.46


      0.48

      Termination fee


      —


      —


      —


      —


      —


      —


      (0.68)

      Acceleration of stock compensation expense due to executive officer resignation


      —


      —


      —


      —


      —


      —


      0.04

      Allocation to unvested restricted stock awards


      (0.01)


      —


      0.02


      (0.01)


      0.02


      0.01


      0.04

      Funds from operations per share attributable to Alexandria's common
         stockholders – diluted, as adjusted


      $         1.97


      $         1.95


      $         1.93


      $         1.91


      $         1.84


      $         7.76


      $         7.30
















      Weighted-average shares of common stock outstanding – diluted


      154,307


      151,561


      146,058


      137,688


      133,827


      147,460


      126,490
















      SOURCE Alexandria Real Estate Equities, Inc.

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