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Altogen Biosystems Provides In Vivo Tissue Transfection Kits


News provided by

Altogen Biosystems

Sep 09, 2014, 06:40 ET

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LAS VEGAS, Sept. 9, 2014 /PRNewswire/ -- Altogen Biosystems (www.altogen.com), a manufacturer of reagents for biological research, offers a broad range of animal in vivo transfection kits targeted to a specific tissue type. The Company provides transfection reagents that enable tissue-targeted delivery of plasmid DNA expression vectors, small RNA therapeutic molecules (siRNA and microRNA), and proteins (http://www.altogen.com/mirna.php). In vivo transfection kits are laboratory tested in both mice and rats to provide effective intracellular delivery via various administration routes, including intravenous, intraperitoneal, and intratumoral injection, while not inducing an inflammatory response.

Development of novel medicines often depend on successful delivery of therapeutic molecules to the target cells and tissues. Altogen Biosystems developed tissue-targeted gene delivery technologies for many tissues, including liver, pancreas, and kidney. These kits are crucial experimental tools for oncology studies, diabetes, cirrhosis, and many other conditions.

Altogen Biosystems provides invivo transfection protocols, dosing advice and expert technical support to enable protein expression and gene silencing studies. Laboratory-proven murine delivery systems are based on cationic lipids, PEGylated liposomes, nanoparticles, or polymeric methods to achieve targeted tissue biodistribution. These complexes protect therapeutic cargo molecules and facilitate transport of the experimental molecules across the cell membrane.

Altogen in vivo transfection line of products includes:

PANCREAS-targeted In Vivo Transfection Kit
LIVER-targeted In Vivo Transfection Kit
KIDNEY-targeted In Vivo Transfection Kit
LIPID In Vivo Transfection Reagent
POLYMER In Vivo Transfection Reagent
NANOPARTICLE In Vivo Transfection Reagent
PEG-Liposome In Vivo Transfection Reagent

In vivo transfection kits supplemented by over 100 pre-optimized in vitro transfection reagents for cancer cell lines, electroporation buffers, and transfection controls (GFP plasmids, inducible expression DNA constructs, siRNA molecules that induce apoptosis, cell cycle arrest, or serve as a non-silencing RNA control in gene silencing experiments).

About Altogen Biosystems

Altogen Biosystems is a life sciences company based in Las Vegas, NV. Company scientists utilize their expertise in combinatorial chemistry and cell and molecular biology to develop advanced transfection technologies. As one of the leading developer of transfection products for biomedical research, Altogen Biosystems has been providing the research community in the United States and worldwide with state-of-the-art components for in vivo and in vitro experiments for almost a decade.

Contact

Altogen Biosystems
848 Rainbow Blvd #823
Las Vegas, NV 89107 USA
Tel: (702) 349-6103
Fax: (702) 989-0841
E-mail: [email protected]

SOURCE Altogen Biosystems

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