AO+ Probiotic Topical Mist Returns -- Now in Two New Higher-Concentration Formulas

The original topical probiotic, previously sold under the Mother Dirt brand, relaunches adding two new higher concentration 2x Pro and 5x Max versions in response to customer demand

CAMBRIDGE, Mass., Oct. 20, 2026 /PRNewswire/ -- AOBiome, the inventor and sole manufacturer of every bottle of AO+ Mist ever sold — including those sold under the Mother Dirt name — today announced the relaunch of the AO+ Probiotic Topical Mist, along with two new higher-concentration formulas: AO+ Pro Mist (2x concentration) and AO+ Max Mist (5x concentration).

Key facts:

• The AO+ Mist, originally launched in 2014, is the first patented topical probiotic of its kind
• Trusted by more than 100,000 customers
• Suitable for all skin types, including problem skin
• Most customers see and feel results within 2 to 4 weeks
• Just four natural ingredients — simple and safe

An accidental beginning

The AO+ Mist story began in 2014, when The New York Times published "My No-Soap, No-Shampoo, Bacteria-Rich Hygiene Experiment", providing reporter Julia Scott's first-person account of using the AO+ Mist for 30 days. The response to the article was overwhelming, and a category-defining skincare product was born.

The science: restoring what modern life wiped out

AO+ Mist is powered by patented ammonia-oxidizing bacteria (AOB). On the skin, AOB convert the ammonia in sweat into by-products that are beneficial to the look and feel of your skin, including helping maintain a healthy skin pH and keeping other microorganisms in balance.

• Improves skin's clarity, tone, and texture for skin that looks and feels smoother
• Restores balance to dry, oily, and problem skin
• Improves the appearance of pores, fine lines, and wrinkles
• Good for sensitive skin - no harsh chemicals, preservatives, or fragrances
• Safe to use anywhere on skin: face, scalp, underarms, back, groin, hands, feet, etc.

About AOB

AOB once lived naturally on human skin. But over the past century, less time outdoors and the daily use of modern soaps and personal-care products have effectively eliminated them. AOB are a critical part of the nitrogen cycle and are found on nearly every living plant and animal — except modern humans.

"Our relationship with bacteria is misunderstood. We've been taught that any bacteria on the skin is problematic, and somewhere along the way we started confusing clean with sterile. In reality our skin requires having an active and diverse population of bacteria to promote health. Nearly 20 years ago, Jamie Lee Curtis and Activia Yogurt taught us about the importance of restoring good bacteria to the gut to support our overall well-being. At AOBiome, we believe the same is true for the skin." said Jim Hoffman, co-founder of AOBiome Cosmetics.

Availability

The AO+ Probiotic Topical Mist, Pro Mist (2x), and Max Mist (5x) are available now at https://aobiomecosmetics.com.

About AOBiome Cosmetics

AOBiome has pioneered the science of beneficial skin bacteria and topical probiotics for more than 12 years. The company invented and manufactures the AO+ Mist and holds numerous patents on its ammonia-oxidizing bacteria technology.  AOBiome Cosmetics is a division of AOBiome Therapeutics, Inc.

Media Contact
Jim Hoffman
[email protected]
+1.617.639.9980
AO+ Mist EPK

SOURCE AOBiome Therapeutics