Blood: The Worldwide Market for Blood Products, Blood Testing, Blood Equipment, and Synthetic Blood Products
LONDON, April 29, 2014 /PRNewswire/ -- Reportbuyer.com has added a new market research report:
Blood: The Worldwide Market for Blood Products, Blood Testing, Blood Equipment, and Synthetic Blood Products
http://www.reportbuyer.com/pharma_healthcare/medical_supplies/blood_worldwide_market_blood_products_blood_testing_blood_equipment_synthetic_blood_products.html
The global blood industry has experienced strong growth in recent years and although this brisk expansion will slow somewhat as products continue to mature and pricing pressures increase, growth will remain solid though 2017 as a result of aging populations in the U.S., Europe and Japan; ongoing technology advancements/new product introductions and indications; expansion of health coverage in the U.S. via health care reform; and continued strong promotion of blood donation by collection agencies.
This study provides an analysis of all the key market segments involved in this industry, including products, equipment and testing.
A variety of infectious agents can be present in blood, including viruses (e.g., HIV-1, hepatitis B and C, HTLV, West Nile virus), bacteria, protozoans, Chagas disease, Lyme Disease and prions (e.g., the agent of variant Crueutzfeldt-Jakob disease, which is the human form of mad cow disease). As of 2013, the main residual risk is due to hepatitis B virus - ranging from 10 in Spain to 1.6 per million donations in France and Germany – although other conditions such as variant Creutzfeldt-Jakob disease (vCJD) or HIV may pose high risk in certain regions.
Testing markets covered include:
• Blood Banking and Plasmapheresis Testing
• Blood Typing
• Human Immunodeficiency Virus (HIV) Testing
• Hepatitis A Virus Testing
• Hepatitis B Virus Testing
• Hepatitis C Virus Testing
• Human T-Cell Leukemia Virus Testing
• West Nile Virus Testing
• Other Safety Testing
The market for human blood and blood components continues to expand as a result of the growing and aging populations, particularly in the developed nations. Aside from RBCs, other blood products are also often required in such procedures. Organ transplants, for example, typically require platelets, cryoprecipitate and frozen plasma. Synthetic blood products are not derived from human blood, but instead represent oxygen-carrying volume-replacement solutions. Although efforts are underway to develop artificial cells or to culture red blood cells (RBCs) from stem cells, present synthetic blood products do not contain cells, antibodies, coagulation factors, or any of the other myriad components of blood itself. One of the primary reasons for their development is to ease the projected shortage in the blood supply.
Blood products covered in the report include:
• Red Blood Cells (RBCs)
• Immunoglobulins
• Albumin
• Other Plasma Products
• Synthetic HBOC and PFC Agents
• Recombinant Factors
Donated blood is collected by specialized collection centers. After collection, whole blood is separated into its three main components: red blood cells (RBCs), platelets, and plasma. Sometimes a fourth component called cryoprecipitate (a fraction of plasma highly concentrated in some clotting factors such as Factor VIII or antihemophilic factor, fibrinogen, and von Willebrand factor) is also generated. Several different types of organizations currently collect blood. While most operate on a not for profit basis, some pay donors.
Blood equipment revenues and forecasts are provided for:
• Blood Collection Equipment
• Automated Blood Collection Equipment
In addition to complete market data, including forecasts to 2017, the study reports:
• Product demand estimates by region
• Collection and transfusion estimates
• High-blood-loss procedure estimates
• Reimbursement rates
• Epidemiology of key conditions requiring blood products
• Products on the market and in development
CHAPTER ONE: EXECUTIVE SUMMARY
THE GLOBAL BLOOD INDUSTRY
SCOPE AND METHODOLOGY
OVERVIEW
Blood Collection
Blood Typing and Testing for Diseases
Blood Testing
Blood Storage And Processing
Blood Transfusions
Blood Management And Safety Issues
Synthetic Blood Products
Blood Products Market
Blood Testing And Typing Products Market
Plasma and Blood Collection Equipment Market
Synthetic Blood Products Market
CHAPTER TWO: OVERVIEW
The Global Blood Industry
History of the Blood Industry
United States
Europe
Asia
Current Blood Industry Issues
Effects of the Economy
Changes from Health Care Reform
Demographic Shifts
Blood and its Components
Red Blood Cells (Erythrocytes)
White Blood Cells (Leukocytes)
Platelets
Plasma
Immunoglobulin Products
Blood Transfusions
Diseases Contracted from Blood Transfusions and Related Identification Testing
Donor Deferral and Special Populations of Donors
Efforts to Create a Virus-Free Blood Supply
Plasma Treatment
Red Blood Cell Treatments
Synthetic Blood Products
Blood Volume Expanders
Hemoglobin Based Oxygen Carriers
Immunologic Properties
Vasoactive Properties
Performance
Perflurocarbon (PFC) Based Blood Products
Developmental Status
Commercialization Challenges
Factor Products for Hemophilia A
Synthetic Platelets
CHAPTER THREE: THE BLOOD MANAGEMENT SYSTEM: BLOOD COLLECTION, PROCESSING AND USE
Blood Collection
Organizations Collecting Blood
Not For-Profit Blood Collection
Red Cross
Community Blood Banks
Hospitals
Other Blood Collection Sites
For-Profit Blood Collection
National Donor Deferral Registry
Donor Donation Demographics
Donor Recruitment
Blood Screening and Evaluation
Methods for Collecting Blood from Donors
Manual Blood Collection
Automated Blood Collection
Plateletpheresis
Leukopheresis
Red Blood Cell Apheresis
Cord Blood Collection
Plasma Collection
Plasma Fractionators
Distributors/Brokers
Blood Typing and Testing for Diseases
Blood Typing
Methods of Blood Typing
Manual Blood Typing Methods
Automated Blood Typing and Screening Methods
Blood Testing
Nucleic Acid Amplification Testing (NAT)
Polymerase Chain Reaction (PCR) Amplification
CBER Licensed PCR Screening Tests
Immunoassay
Enzyme-Linked Immunosorbent Assay
Basic ELISA
Alternate ELISA Methods
Sandwich Method
Reverse Sandwich Method
Reverse Sandwich Inhibition Method
Costs and Other Barriers
Blood Storage
Blood Processing
Cohn Fractionation
Newer Fractionation Methods
Advanced Fractionation Methods
Cascade Plasma Fractionation
Automated Fractionation
Blood Transfusions
Testing Before Transfusion
Coombs Test
Manual Cross-Match Techniques
Major Cross-Match
Minor Cross-Match
Antibody Screen
Types of Transfusions
Whole Blood
Packed Red Blood Cells
Platelets
Leukocytes
Fresh Frozen Plasma (FFP)
Cryoprecipitate
Immune Serum Globulin/IMIG/IGIV
Factor IX and Factor IX Complex
C1 Inhibitor
Fibrin/Thrombin
Therapeutic Apheresis
Blood Management Issues
Availability
Safety Issues
Reducing Blood Typing Errors
Improving Donor Screening
Improving Viral Screening
Increasing Repeat Donation Rates
Enhancing Viral Inactivation Processes
Increasing Voluntary Donation
Preventing Bacterial Infections
Biovigilence
Other Safety Precautions
CHAPTER FOUR: THE HUMAN BLOOD AND BLOOD PRODUCTS MARKET
Driving Forces of the Human Blood Industry
Variables Influencing the Demand for Blood Transfusions
Market Size
Changing Patterns of Transfusion Procedures
Leukocyte Reduction
Impact of Autologous Donations
Types of Autologous Donations
Pricing of Blood
National Blood Exchange
RBCs and Leukoreduced RBCs
Washed Red Blood Cells
Deglycerolized Red Blood Cells
Single-Donor Platelets and Random-Donor Platelets
Fresh Frozen Plasma and Pooled Frozen Plasma
Cryoprecipitate
Granulocytes
Gamma-Irradiated Blood
Average Cost of Transfusion
Plasma and Plasma Derived Products
Plasma Market Size
Market Dynamics
Immunoglobulins
Immunoglobulin Market Dynamics
Immunoglobulin Market Size
Hepatitis B Immunoglobulin
RhoD Immunoglobulin
Tetanus Immunoglobulin
Rabies Immunoglobulin
Varicella Immunoglobulin
Vaccinia Immunoglobulin
Novel Immunoglobulins
Albumin
Albumin Market Dynamics
Albumin Market Size
Prothrombin Complex Concentrates
Alpha-1 Proteinase Inhibitors
Fibrin Sealants
Clotting Factors and Factor VIIa
CHAPTER FIVE: THE BLOOD TESTING AND TYPING MARKETS
Blood Testing Products for Donor Screening
Market Size
Latin America
China
Immunoassays
Nucleic Acid Testing
Market Participants
Immunoassays
Nucleic Acid Testing
Blood Typing Products
Market Size
Market Participants
Plasma and Blood Collection Equipment
Market Size
Market Participants
CHAPTER SIX: SYNTHETIC BLOOD PRODUCTS MARKET
Driving Forces of the Synthetic Blood Products Industry
Variables Influencing the Supply and Demand of Donated Blood
Recombinant Factor Market
Market Size
Market Participants
Oxygen Carrier Market
Market Size
Synthetic Blood Products in Clinical Development
Hemopure (OPK BioTech)
Oxygent (Sanguine Corp.)
Oxycyte (Oxygen Biotherapeutics)
Perftoran (Perftoran)
PHER-O2 (Sanguine Corp.)
MP4OX (Sangart)
Advate (Baxter)
Recombinant Factors
Stem Cell Approaches
Other Research Initiatives
Jerome H. Holland Laboratory
Program in Cellular and Molecular Medicine
National Blood Foundation
CHAPTER SEVEN: TOTAL BLOOD PRODUCTS MARKET
The Blood Products Industry
Market Size
CHAPTER EIGHT: COMPANY PROFILES
AABB
Abbott Laboratories
America's Blood Centers
American Red Cross
Baxter International
Bio-Rad Laboratories
BioTime Inc.
Gen-Probe Inc. /Hologic
Fenwal/Fresenius Kabi
Grifols Biologicals, Inc.
Novartis Diagnostics
Novo Nordisk A/S
OPK BioTech
Oxygen Biotherapeutics
Perftoran
Roche
Sanguine Corp.
LIST OF EXHIBITS
CHAPTER ONE: EXECUTIVE SUMMARY
Exhibit 1-1
Global Blood Products Market, 2012
Exhibit 1-2
Total Global Market for Blood Collection Equipment: 2007 – 2017
Exhibit 1-3
Recombinant Factor and High Blood Loss Market: 2012 - 2017
CHAPTER TWO: OVERVIEW
Exhibit 2-1
Timeline of Global Blood Industry Development 1922 - 2013
Exhibit 2-2
Composition of Blood Plasma
Exhibit 2-3
Viral Inactivation Methods for Viruses Found in Platelets
Exhibit 2-4
Viral Inactivation Methods for Viruses Found in Red Blood Cells
CHAPTER THREE: THE BLOOD MANAGEMENT SYSTEM: BLOOD COLLECTION, PROCESSING AND USE
Exhibit 3-1
Worldwide Annual Blood Collection by Component
Exhibit 3-2
Basic Blood Types
Exhibit 3-3
Blood Transfusion Compatibility
Exhibit 3-4
PCR-Based Screening Tests Licensed by CBER
Exhibit 3-4 (cont'd.)
PCR-Based Screening Tests Licensed by CBER
Exhibit 3-5
Comparison of Direct and Indirect ELISA Tests
Exhibit 3-6
Results of Cohn Fractionation Method
Exhibit 3-7
Plasma Proteins of Therapeutic Interest
Exhibit 3-8
Factor VIII Products in Development, 2013
Exhibit 3-11
Risk of Contamination
Exhibit 3-12
Viral Inactivation by Procedure
CHAPTER FOUR: THE HUMAN BLOOD AND BLOOD PRODUCTS MARKET
Exhibit 4-1
Geographical Distribution of RBC Demand by Region (United States, Europe, Japan, ROW), 2012
Exhibit 4-2
Projected World Demand for RBCs, 2012-2017
Exhibit 4-3
Worldwide Demand for RBCs for Acute and Chronic Conditions, 2012
Exhibit 4-4
Number of High Blood Loss Surgical Procedures by Type, 2012
Exhibit 4-5
Average Blood and Component Requirements by Condition
Exhibit 4-6
Global Blood Products Market by Type, Number of Units, Average Price and Total Value, 2012
Exhibit 4-7
Global Blood Collection and Transfusion Estimates (Millions of Units), 2012-2017
Exhibit 4-8
Global Plasma Collection and Transfusion Estimates , 2012-2017
Exhibit 4-9
Countries Conducting Routine Leukocyte Reduction, 2013
Exhibit 4-10
Surgical Procedures Amenable to Autologous Blood Donation
Exhibit 4-11
CMS Blood Product Reimbursement Rates, 2013
Exhibit 4-12
CMS Blood Transfusion Reimbursement Rates, 2013
Exhibit 4-13
Selected Plasma Derived Product Approvals, 2005 - 2012
Exhibit 4-14
The Global Market for Plasma and Plasma Derived Products, 2007 - 2017
Exhibit 4-15
Selected Plasma Industry Shifts, 2003 - 2012
Exhibit 4-16
Sales and Market Shares of Leading Suppliers of Plasma and Plasma Derived Products, 2012
Exhibit 4-17
Global Market for Immunoglobulins by Manufacturer 2012 - 2017
Exhibit 4-18
Global Market for Human Albumin Products by Brand, 2012 - 2017
Exhibit 4-20
Leading Factor IX Products, 2013
CHAPTER FIVE: THE BLOOD TESTING AND TYPING MARKETS
Exhibit 5-1
Total Global Market for Immunoassay versus Nucleic Acid Testing Equipment: 2007 – 2017
Exhibit 5-2
Global Blood Banking and Plasmapheresis Testing by Molecular Diagnostics: 2012 – 2017
Exhibit 5-3
U.S. Blood Banking and Plasmapheresis Testing by Molecular Diagnostics: 2012 – 2017
Exhibit 5-4
Global Projected Blood Banking and Plasmapheresis Molecular Diagnostics Testing Market Potential: 2012 – 2017
Exhibit 5-5
Projected Blood Banking and Plasmapheresis Molecular Diagnostics Testing Market Potential in the United States: 2012 – 2017
Exhibit 5-6
Selected Commercially Available Molecular (Nucleic Acid) Tests for Blood, Plasma and Organ Donor Screening in the United States, 2005 - 2012
Exhibit 5-7
Total Global Market for Blood Collection Equipment: 2007 – 2017
Exhibit 5-8
Global Market for Automated Blood Collection Equipment: 2007 – 2017
CHAPTER SIX: SYNTHETIC BLOOD PRODUCTS MARKET
Exhibit 6-1
World Recombinant Factor Market by Brand, 2010 - 2017
Exhibit 6-2
High Blood Loss Market HBOC and PFC Agent Revenues 2012 - 2017
Exhibit 6-3
Leading Recombinant Factor Products in Clinical Trials, 2013
CHAPTER SEVEN: TOTAL BLOOD PRODUCTS MARKET
Exhibit 7-1
Global Blood Products Market by Segment, 2012
Exhibit 7-2
Global Blood Products Market Forecast by Segment, 2012 -
Exhibit 7-3
Global Blood Products Market by Segment, 2017
CHAPTER EIGHT: COMPANY PROFILES
Read the full report:
Blood: The Worldwide Market for Blood Products, Blood Testing, Blood Equipment, and Synthetic Blood Products
http://www.reportbuyer.com/pharma_healthcare/medical_supplies/blood_worldwide_market_blood_products_blood_testing_blood_equipment_synthetic_blood_products.html
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