COTA partners with LCP Health Analytics to advance the use of US RWD to support HTA decision making internationally

US + UK Data to Address Key Evidence Gaps in Access to Medicines

NEW YORK, July 30, 2025 /PRNewswire/ -- LCP Health Analytics is partnering with COTA to explore how US real-world data (RWD) can support health technology assessments (HTA) in the United Kingdom (UK) and European Union (EU). With growing recognition that European patients may be underserved by delays in accessing new health technologies, this initiative explores whether deidentified US multiple myeloma patient data can be leveraged to inform reimbursement decisions and accelerate access to new treatments in the UK.

By combining COTA's rich oncology data with LCP's analytical expertise supporting HTA decision-making, this partnership will develop and test methods for identifying US patient groups that closely resemble those treated under NHS guidelines in the UK. This collaboration represents the first direct comparison of US and UK real-world haematological oncology data, offering unique insights and addressing historical challenges in cross-country data access and use in the UK.

Once comparable groups are identified, the project will undertake several steps to evaluate their suitability for inclusion in UK and EU HTAs. Evaluative criteria include:

• Characterisation of patient groups using clinical and demographic data
• Examination of treatment patterns and key outcomes, such as survival rates, relevant to payers and HTA bodies
• Assessment of the potential to use these groups in future real-world studies to emulate clinical trial populations

This partnership leveraging COTA's US oncology real world dataset directly follows LCP Health Analytics' recent expansion through launching their US Access Solutions in June this year.

"We are excited about this new partnership and the insights that can be gained from the project," said Dr Ben Bray, Partner and Evidence Generation Lead at LCP Health Analytics. "By combining UK and US healthcare data and expertise, we can generate evidence to support HTA submissions and hopefully expedite access to new treatments. We hope to see more collaborative efforts like this in the future."

COTA's high-quality, comprehensive oncology real-world data (RWD) is sourced from electronic health records and reflects a 50/50 mix of academic and community care settings across the US. Its suite of artificial intelligence abstraction and curation tools will help remove the barriers to faster, more efficient RWD analyses and insight generation at scale.

Historically, the UK has relied on US clinical trial data for regulatory approvals and HTA evaluations while seeking country-specific RWD. This collaboration aims to bridge that gap. By incorporating diverse US RWD from COTA, we hope to achieve a more comprehensive understanding of the methods for identifying UK relevant treatment groups and how these cohorts can be used to support groundbreaking developments reaching the right patients, at the right time.

"The US produces huge quantities of rich healthcare data," said Dr Andrew Thompson, Senior Epidemiologist at LCP Health Analytics. "Exploring ways to use this in the UK context is a key step in generating robust evidence and driving regulatory innovation for the benefit of patients."

"Real-world data and AI have expanded what was once possible for cancer treatments, yet fragmentation and regulatory nuances continue to add complexity and confusion", said CK Wang, MD, Chief Medical Officer of COTA. "Our collaboration with LCP Health Analytics will enable regulatory bodies and life sciences organizations to leverage more comprehensive and robust data sets of patient cohorts to accelerate treatment at a global scale.

About LCP

We have market-leading capabilities across pensions and financial services, energy, health and sports analytics and bring a breadth of knowledge and specialist skills that help our clients solve problems and embrace opportunities. 

Behind every piece of data, there are numerous possibilities. By fusing human instinct with analytical insight to identify sparks of opportunity, we help our clients navigate clearly through complexity to make decisions that matter to their business and to our wider society. We are powered by our desire to solve important problems to create a positive future.

Visit www.lcp.uk.com for more information. LCP has around 1200 experts based at locations in London, Winchester, Edinburgh, Cambridge and Paris. 

About COTA, Inc.

Founded by oncologists, COTA is committed to creating a precise, patient-first approach to cancer care using real-world data. The company leverages technology-supported data abstraction methods to make sense of complex, fragmented patient data from the real world. Offering the highest quality oncology real-world data from leading academic and community-based cancer centers and an advanced analytics platform, COTA partners with leading life sciences companies, providers, and payers to ensure that everyone touched by cancer has a clear path to the right care. To learn more about COTA and how to fast-track improvements in cancer care and treatment with comprehensive and diverse real-world data and analytics, visit cotahealthcare.com.

Press Contacts

For COTA
Jared Rosen
[email protected]

For LCP
Lauren Keith
[email protected] 

SOURCE Cota, Inc.