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De años a solo un mes: el modelo de moléculas de medicamentos Pangu de Huawei Cloud acelera el descubrimiento de nuevos fármacos
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News provided by

HUAWEI CLOUD

Sep 19, 2022, 12:35 ET

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BANGKOK, 19 de septiembre de 2022 /PRNewswire/ -- El 19 de septiembre, HUAWEI CONNECT 2022 comenzó en Bangkok, Tailandia. En el evento, el Sr. Ken Hu, presidente rotativo y en funciones de Huawei, pronunció un discurso de apertura titulado "Unleash Digital" ("Liberar lo digital"), en el que habló sobre cómo la empresa está ayudando a las organizaciones a aprovechar al máximo la nube para lograr un desarrollo a pasos agigantados.

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El Sr. Ken Hu pronuncia su discurso en HUAWEI CONNECT 2022 (PRNewsfoto/HUAWEI CLOUD)
El Sr. Ken Hu pronuncia su discurso en HUAWEI CONNECT 2022 (PRNewsfoto/HUAWEI CLOUD)

Durante su discurso, el Sr. Ken Hu habló sobre cómo el Primer Hospital Afiliado de la Facultad de Medicina de la Universidad Jiaotong en Xi'an utilizó la IA para acelerar la I+D farmacéutica y el descubrimiento de nuevos fármacos.

En la industria farmacéutica, en promedio se necesitan más de USD 1.000 millones y 10 años para poner un nuevo medicamento en el mercado, desde el desarrollo hasta la aprobación. Durante el desarrollo de antibióticos, se ha observado que a veces se descubren bacterias resistentes incluso antes de que los nuevos antibióticos desarrollados finalicen los ensayos clínicos.

Utilizando un servicio de diseño de medicamentos asistido por IA e impulsado por el modelo de moléculas de medicamentos Pangu de Huawei Cloud, el profesor Liu Bing del Primer Hospital Afiliado de la Facultad de Medicina de la Universidad de Jiaotong en Xi'an y su equipo desarrollaron un nuevo medicamento antimicrobiano de amplio espectro en solo un mes, y los costos de I+D se redujeron en un 70 %.

Un gran desafío en el descubrimiento de nuevos fármacos es el cribado de los cientos de millones de moléculas de fármacos existentes. Tradicionalmente, el cribado de fármacos fue realizado por expertos en laboratorios, lo cual era costoso, lento y tenía una alta tasa de fracaso.

El modelo de moléculas de medicamentos Pangu de Huawei Cloud ha sido entrenado utilizando los datos de 1.700 millones de moléculas de medicamentos, y puede predecir las propiedades fisicoquímicas de los compuestos de fármacos y calificarlos en función de su capacidad farmacológica. Los investigadores pueden realizar experimentos dirigidos para verificar los compuestos farmacológicos que tienen las puntuaciones más altas.

Además, el optimizador de estructuras moleculares del modelo de moléculas de medicamentos Pangu se puede utilizar para optimizar la estructura de los principales compuestos, a fin de minimizar los posibles efectos secundarios de los nuevos fármacos en las células humanas normales.

Hoy en día, la nube se ha convertido en un importante medio para las empresas digitales. Huawei Cloud ofrece cuatro líneas de desarrollo. Una de ellas es la línea de desarrollo de IA ModelArts, a la que los clientes y socios de todas las industrias pueden acceder a pedido a fin de poder dejar el lado técnico de la innovación digital a Huawei Cloud y dedicar su atención a lo que más les importa.

Foto:  https://mma.prnewswire.com/media/1901471/Ken_Hu_HUAWEI.jpg

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