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El COVID-19 provoca mayor riesgo de desarrollar trastornos neurodegenerativos
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EAN Congress 2022

Jun 24, 2022, 18:01 ET

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- Congreso EAN 2022: Pacientes positivos a COVID-19 presentan un mayor riesgo de desarrollar trastornos neurodegenerativos, muestra un nuevo estudio

Los pacientes ambulatorios positivos para COVID-19 tienen un mayor riesgo de trastornos neurodegenerativos en comparación con las personas que dieron negativo para el virus, según ha demostrado un nuevo estudio presentado hoy en el 8.º Congreso de la Academia Europea de Neurología (EAN).

VIENA, 24 de junio de 2022 /PRNewswire/ -- El estudio, que analizó los registros de salud de más de la mitad de la población danesa, encontró que aquellos que habían dado positivo por COVID-19 tenían un mayor riesgo de enfermedad de Alzheimer, enfermedad de Parkinson y accidente cerebrovascular isquémico.

De las 919.731 personas que realizaron la prueba de COVID-19 en el estudio, los investigadores encontraron que las 43.375 personas que dieron positivo tenían un riesgo 3,5 veces mayor de ser diagnosticadas con la enfermedad de Alzheimer, 2,6 veces con la enfermedad de Parkinson, 2,7 veces con un accidente cerebrovascular isquémico y un 4,8 veces mayor con hemorragia intracerebral. Si bien la neuroinflamación puede contribuir a un desarrollo acelerado de los trastornos neurodegenerativos, los autores destacaron las implicaciones del enfoque científico en las secuelas a largo plazo después de la COVID-19.

El estudio analizó pacientes hospitalizados y ambulatorios daneses entre febrero de 2020 y noviembre de 2021, así como pacientes con gripe del período previo a la pandemia correspondiente. Los investigadores utilizaron técnicas estadísticas para calcular el riesgo relativo y los resultados se estratificaron por estado de hospitalización, edad, sexo y comorbilidades.

El doctor Pardis Zarifkar, autor principal del Departamento de Neurología, Rigshospitalet, Copenhague, Dinamarca, explicó: "Más de dos años después del inicio de la pandemia de COVID-19, la naturaleza precisa y la evolución de los efectos de COVID-19 en los trastornos neurológicos permaneció sin caracterizar. Estudios previos han establecido una asociación con síndromes neurológicos, pero hasta ahora se desconoce si el COVID-19 también influye en la incidencia de enfermedades neurológicas específicas y si difiere de otras infecciones respiratorias".

Sin embargo, el mayor riesgo de la mayoría de las enfermedades neurológicas no fue mayor en los pacientes con COVID-19 positivo que en las personas a las que se les había diagnosticado gripe u otras enfermedades respiratorias. Los pacientes con COVID-19 tenían un riesgo 1,7 veces mayor de accidente cerebrovascular isquémico en comparación con la gripe y la neumonía bacteriana en pacientes mayores de 80 años.

La frecuencia de otras enfermedades neurodegenerativas como la esclerosis múltiple, la miastenia grave, el síndrome de Guillain-Barré y la narcolepsia no aumentó después de la COVID-19, la gripe o la neumonía.

El doctor Pardis Zarifkar añadió: "Estos hallazgos informarán nuestra comprensión del efecto a largo plazo de COVID-19 en el cuerpo y el papel que desempeñan las infecciones en las enfermedades neurodegenerativas y los accidentes cerebrovasculares".

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