HER2-positive Gastric Cancer Market is Contemplated to Observe a Moderate Growth Rate of CAGR 3.11% for the Study Period 2018-30, Analyses DelveInsight

The unexplored market of HER2-positive Gastric Cancer is expected to observe growth which is accredited to factors such as understanding of the disease, increase in awareness and better management of the disease, also many key pharmaceuticals like AstraZeneca, Bayer, Bristol-Myers Squibb, and others are entering the disease domain to propel the HER2-positive Gastric Cancer market share

LAS VEGAS, Oct. 20, 2021 /PRNewswire/ -- DelveInsight's HER2-positive Gastric Cancer Market report offers a detailed comprehension of HER2-positive Gastric Cancer market size by treatment, epidemiology, emerging therapies, market drivers and barriers, current and forecasted HER2-positive Gastric Cancer market size from 2018 to 2030 segmented into the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), Japan, China, and South Korea.

Salient features from the HER2-positive Gastric Cancer Market Insight report

• According to an estimate by DelveInsight, China has the largest incident population of HER2-positive Gastric Cancer.
• The market size for HER2-positive Gastric Cancer was USD 1,138.1 million in 2020 in the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), Japan, China, and South Korea, and is estimated to grow at a CAGR of 3.11% during the forecast period. 
• Key pharma players working proactively in the HER2-positive Gastric Cancer therapeutic market are AstraZeneca, Bayer, Bristol-Myers Squibb, Ono Pharmaceutical Co. Ltd, Hutchison Medipharma, LintonPharm, Shanghai Henlius Biotech, MacroGenics/Zai Lab, and several others that will lead to a significant increase in the market size during the forecast period.
• The key therapies expected to launch in the HER2-positive Gastric Cancer market include Durvalumab, Regorafenib, Ipilimumab, Fruquintinib, Catumaxomab, Serplulimab, Margetuximab, and others.
• DelveInsight analyses the market size of HER2-positive Gastric Cancer, which is anticipated to increase during the study period, 2018–2030. It is due to the fact that the current understanding of HER2-positive Gastric Cancer has greatly improved in recent decades, leading to growing awareness, improved management, and better outcomes.

For further information on Market Impact by Therapies, Download HER2-positive Gastric Cancer Market sample @ HER2-positive Gastric Cancer Market Landscape   

Gastric Cancer arises from the inner lining of stomach walls and afterwards penetrates deep into the stomach walls as the development of tumour progresses. There are several different types of cancer that usually occur in the stomach, among which almost 90% of gastric cancers constitute adenocarcinoma. HER2 overexpression or amplification occurs in 20% of GCs.

The quantification of HER2-positivity is determined by various laboratory tests like immunohistochemistry (IHC) or by measurement of the number of HER2 gene copy numbers by fluorescent in-situ hybridization (FISH) techniques.

HER2-positive Gastric Cancer Epidemiology Segmentation

DelveInsight's analysis indicates that the incident cases of HER2-positive Gastric Cancer associated in 7MM + China + South Korea countries were 170,868 in 2020. Out of which, China has the largest incident population of HER2-positive Gastric Cancer.

The HER2-positive Gastric Cancer Report proffers epidemiological analysis for the study period 2018-30 in the 7MM segmented into:

• Total Incident Cases of HER2-positive Gastric Cancer
• Gender-specific Cases of HER2-positive Gastric Cancer
• Age-specific Cases of HER2-positive Gastric Cancer
• Stage-specific Cases of HER2-positive Gastric Cancer

Know how HER2-positive Gastric Cancer Epidemiological Trends are going to look like in 2030 by downloading @ HER2-positive Gastric Cancer Epidemiological Insights.

HER2-positive Gastric Cancer Market Outlook

Trastuzumab has emerged as the first targeted drug to improve overall survival when combined with chemotherapy in advanced HER2-positive Gastric Cancer. New families of targeted drugs include TRK inhibitors such as Rozlytrek, antibody-drug conjugates such as Aidixi, and monoclonal antibodies such as nivolumab, which could offer alternative treatment when trastuzumab fails.

Gastric Cancer is the third leading cause of cancer mortality in the world. In western countries, most of the patients are diagnosed when the tumour is at an unresectable stage. Key pharmaceutical companies that are working efficiently in the HER2-positive Gastric Cancer space include names like AstraZeneca, Bayer, Bristol-Myers Squibb, Hutchison Medipharma, LintonPharm, Shanghai Henlius Biotech, Jiangsu HengRui Medicine, Seagen, MacroGenics/Zai Lab, Merck Sharp & Dohme Corp., Eisai Inc, Merus N.V., OncXerna Therapeutics, Inc, Eli Lilly and Company, and others.

A few of the novel therapies in advanced HER2-positive Gastric Cancer include Durvalumab, developed by AstraZeneca - it is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody that blocks the interaction of PD-L1 with PD-1 and CD80. Blockade of PD-L1/PD-1 and PD- L1/CD80 interactions releases the inhibition of immune responses without inducing antibody-dependent cell-mediated cytotoxicity (ADCC). PD-L1 blockade with durvalumab increased T-cell activation in vitro and decreased tumour size in co- engrafted human tumor and immune cell xenograft mouse models. Another therapy is Fruquintinib by Hutchison Medipharma Limited, an oral dose, with lower off-target toxicities compared to other targeted therapies. 

Discover more about therapy set to grab substantial HER2-positive Gastric Cancer market share @ HER2-positive Gastric Cancer Market Share.

HER2-positive Gastric Cancer Market: Drivers and Barriers

DelveInsight estimates that the HER2-positive Gastric Cancer market is expected to show positive growth, mainly attributed to increased incidence, increasing disease burden due to the ageing population as well as the development of in-depth understanding of the disease pathogenesis. Also, the presence of a robust pipeline of emerging therapies, clinical development of novel biomarkers, and initiatives by regulatory agencies to advance drug development also play a pivotal role in shifting the market trends for HER2-positive Gastric Cancer.

There is also the presence of certain drawbacks that can obstruct the growth of the HER2-positive Gastric Cancer market such as lack of understanding of intratumoral heterogeneity, erosion in innovator sales, like the launch of biosimilars, lack of universal guidelines for the assessment of HER2 overexpression or amplification, and also the impact of COVID-19 i.e. delay in disease diagnosis which may lead to a significant decline in growth of HER2-positive Gastric Cancer market.

DelveInsight analyses that the treatment landscape for HER2-positive Gastric Cancer is likely to experience huge changes, with the approval of new drugs and drug combinations, in different geographies.

Know which therapy is expected to score the touchdown first @ HER2-positive Gastric Cancer Market Landscape and Forecast.

Scope of the HER2-positive Gastric Cancer Report:

• Study Period: 2018-30
• Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]  + China + South Korea
• Key Companies: AstraZeneca, Bayer, Bristol-Myers Squibb, Ono Pharmaceutical Co. Ltd, Hutchison Medipharma, LintonPharm, Shanghai Henlius Biotech, MacroGenics/Zai Lab
• Key  HER2-positive Gastric Cancer Pipeline Therapies: Durvalumab, Regorafenib, Ipilimumab, Fruquintinib, Catumaxomab, Serplulimab, Margetuximab
• Therapeutic Assessment:  HER2-positive Gastric Cancer current marketed and emerging therapies
• Market Dynamics:  HER2-positive Gastric Cancer market drivers and barriers 
• Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
• Unmet Needs
• KOL's views
• Analyst's views
• Market Access and Reimbursement

Discover more about the future market share of  HER2-positive Gastric Cancer treatment therapies @ HER2-positive Gastric Cancer Market Forecast Outlook

Table of Contents 

Get in touch with our Business executive @ HER2-positive Gastric Cancer Market Landscape Analysis 

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SOURCE DelveInsight Business Research, LLP