NORCROSS, Ga., April 2, 2015 /PRNewswire/ -- Thermo-Rx® brand Acacia Rigidula Extract is a quantum leap in the field of weight loss backed by a clinical study -- one showed an increase in the metabolism by 22% in 45 minutes. The results seen with Thermo-Rx® brand Acacia Rigidula Extract were compared by Hi-Tech Researchers to previous studies on Ephedrine* -- the Gold Standard for OTC diet aids. The findings were amazing as Thermo-Rx® brand Acacia Rigidula Extract was found to be over 20% stronger than 30mg Ephedrine and 82% stronger than 10mg Ephedrine. The findings of the present study indicate that the increase in resting metabolic rate exhibited with 250 mg Acacia Rigidula (12+%) are comparable to the findings of previous studies which reported that 10 to 30 mg ephedrine increased energy expenditure by 6.6% to 10%.
Since the controversy with ephedrine began several several years ago, companies have searched high and low to find an alternative ingredient for their weight loss products. Acacia Rigidula is not only such an alternative, but it may actually be superior to ephedra*. Thermo-Rx® is a unique proprietary plant extract derived from Acacia rigidula. Hi-Tech's overseas supplier worked with Hi-Tech to isolate four active ingredients from the plant. This highly purified plant extract is is standardized to 95% phenylethylamines. The four phenylethylamine alkaloids are chemically similar to ephedrine alkaloids. Phenylethylamine (PEA) is considered by chemists to be the top choice of all stimulants because it is structurally clean and because of its ability to elevate the mood and provide an overall sense of well-being. The alkaloid profile in Thermo-Rx® is unmatched by any other Acacia species due to its phenylethylamine content, as well as numerous other alkaloids and amines. Thermo-Rx® brand Acacia Rigidula Extract is a state-of the-art weight loss ingredient proprietary to and manufactured by Hi-Tech Pharmaceuticals - where science never stands still™!
Phenylethylamine is a sympathomimetic amine found in the leaves of Acacia rigidula. Phenylethylamine also naturally occurs in chocolate, and is responsible for its effects on mood, appetite, and sense of well-being. Phenylethylamine is probably the cleanest stimulant ever researched. Its ability to stimulate the central nervous system without causing a nervous feeling or the "jitters" is remarkable. Phenylethylamine acts on alpha-receptors in the brain, as do norepinephrine and ephedrine. It is also believed by chemists and scientists in the industry to cause the release of dopamine in the pleasure sensing areas of the brain.
With FDA's harsh stance on DMAA-containing supplements, the sale of dietary supplements containing Thermo-Rx® brand Acacia Rigidula Extract has increased dramatically. Hi-Tech has worked diligently over the past 2 years to ramp up raw material production as we continue to get major brands wanting to include this one-of-a-kind weight loss ingredient in their formulas. Hi-Tech has many other major brands launching Acacia products in the next few months.
"The ability to increase our production of this amazing dietary supplement is an important development for men and women who struggle with being overweight and need help with weight management beyond diet and exercise," said Jared Wheat, Hi-Tech's President and Chief Executive Officer. "We thank our entire team and the people who participated in our clinical trial programs for making this achievement possible." Hi-Tech expects Acacia usage to grow, but recommends caution as many companies have tried to use inferior Acacia extracts that are not backed by a clinical study nor contain the Phenylethylamine alkaloid profile necessary to boost the resting metabolic rate. "Acacia rigidula is a lifesaver for the weight loss market and could not have come at a better time considering that more than a third of U.S. adults, 78.6 million, are overweight, according the federal Centers for Disease Control and Prevention," said Wheat.
In the clinical study*, analysis indicated that there were no significant differences between groups in values of VO2 at baseline. However, Acacia produced significantly greater values of VO2 at 1hr, 2hrs, and 3hrs post compared with Placebo and Caffeine displayed significantly greater values over Placebo at 1hr and 2hrs post (p's<0.05). The relative increase of VO2 with Acacia at 1hr and 2hrs (12.0%, 9.3%) was slightly higher than caffeine (9.9%, 8.5%). At 3hrs post ingestion, VO2 with Caffeine reduced to 3.5% over baseline which was no longer significantly different than Placebo. In contrast at 3hrs post ingestion, Acacia was still 12.5% over baseline and was significantly greater than Placebo (p<0.05).
These findings** indicate that Acacia Rigidula promotes significant increases in resting energy expenditure (12+%) still evident 3 hrs post ingestion with modest increases in hemodynamic measures (4-5% for HR, SBP). At this time, it is not known for what time period energy expenditure remains elevated.
- In contrast, 300 mg caffeine produced similar (10%) increases in resting energy expenditure at 1hr post ingestion but values fell dramatically to 3.5% over resting values at 3 hrs post ingestion.
- The differing responses of Acacia Rigidula and Caffeine support the established position that these two compounds exert distinctly different mechanisms.
- The specific responses of Acacia Rigidula and Caffeine suggest that a combination of these compounds may provide effective enhancement of metabolic activity as part of a total weight loss program, without the potentially dangerous hemodynamic stresses associated with products primarily based on central nervous system stimulants.
Acacia rigidula is found in Lipodrene® and other Hi-Tech weight loss products. The alkaloids from Acacia rigidula are biologically similar to those found in ephedra and possess properties that are shared with ephedrine alkaloids. The most obvious similarity is that the Acacia alkaloids, like the ephedra alkaloids, readily pass cross the blood brain barrier. This is because the structures of ephedrine and several of those in Acacia, both possess the B-methyl substituent of the aliphatic side chain, which is characteristic of ephedrine and its congeners, thus further increasing lipophilicity. "Acacia rigidula is just the answer the diet industry has been waiting on for years!" said Wheat.
Thermo-Rx® brand Acacia Rigidula Extract has been used for over a decade by Hi-Tech in many of their Diet & Energy products. Some of the Hi-Tech brands utilizing this Diet & Energy amazing ingredient are as follows: Lipodrene®, Fastin XR®, Fastin® Rapid Release, Black Widow®, Stimerex®-ES, and HydroxyElite® to name a few. Hi-Tech Pharmaceuticals -- one of the industry's largest contract manufacturers -- produces many other top brands weight loss products that have utilized Thermo-Rx® successfully to build top diet products. Some of these products are Jetfuel® Superburn and Jetfuel® T-300 by GAT; Dexaprine® XR, Thermoxyn® and Conquer™ by IFORCE; Black Bombs® by Dorian Yates Nutrition; IFORCE Dexaprine XR Viper Hyperdrive® by ALRI; ThermaLean™ by NICWL; and Phenadrine® by APS Nutrition.
The Acacia Rigidula alkaloids produce extreme energy and promote a sense of well-being. In a recent published study*, these alkaloids produced a 12% increase in metabolic rate at the 3 hour mark. It was compared head-to-head with caffeine and caffeine only produced a 3.5% increase at the 3 hour mark. These results show Acacia is 400% greater at stimulating the metabolic rate than caffeine 3 hours after consumption. This was also 20% stronger than 30mg Ephedrine and 82% stronger than 10mg Ephedrine. If you are interested in trying a product with Thermo-Rx®, all of the Hi-Tech Diet & Energy aids will help you achieve your weight loss goals. "The products by Hi-Tech Pharmaceuticals are all manufactured with Thermo-Rx® brand Acacia rigidula extract, and will help you lose weight and feel great! †" said Wheat.
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to treat, cure, diagnose, or prevent any disease.
Hi-Tech Pharmaceuticals, Inc. is a leading global healthcare supplier that develops, manufactures and distributes dietary supplements, over-the-counter (OTC) and prescription pharmaceuticals, beverages, bulk dietary raw materials, and consumer products. Hi-Tech Pharmaceuticals is an enormously successful company that creates, manufactures and sells high-quality herbal products sold by the large, major retailers across the United States. These retailers include: GNC, Rite Aid, Vitamin Shoppe, NBTY, Kroger, Albertson's, CVS, Kmart, Hannaford, Cardinal Health, Mckesson Corporation, AmerisourceBergen, Harmon Stores, Fred Meyer, Osco Drugs, Supervalu, Roundy's, Sav-On Drugs, Meijer, Fruth Pharmacy, Kinney Drug, Kinray, A&P, Stop & Shop, Giant Eagle, HEB, Winn Dixie, Ingles, Food Lion, Harris Teeter, Bed Bath & Beyond, Amazon.com, and over 5,000 health food retailers and adult novelty stores, as well as in more than 80,000 convenience stores throughout the United States. Hi-Tech owns the brand names Hi-Tech Pharmaceuticals, Advanced Performance Supplements (APS), Nature's Essentials, and ALR Industries.
SOURCE Hi-Tech Pharmaceuticals, Inc.