Holy Name Medical Center Introduces Radium 223, Xofigo®, Novel Treatment For Prostate Cancer

Oct 02, 2013, 13:33 ET from Holy Name Medical Center

TEANECK, N.J., Oct. 2, 2013 /PRNewswire/ -- Holy Name Medical Center's Cancer Center announces today the introduction of Xofigo® (radium 223 dichloride) for the treatment of select patients with advanced prostate cancer.  Holy Name is the only Bergen county facility offering this break through treatment.

In May, the U.S. Food and Drug Administration (FDA) approved Xofigo® (radium Ra 223 dichloride) for the treatment of patients with bone metastasis who have hormone-resistant prostate cancer. Hormone-resistant prostate cancer, also known as androgen-insensitive or castration-resistant prostate cancer is defined by disease progression despite androgen-deprivation therapy and may present as one or any combination of a continuous rise in serum levels of prostate-specific antigen (PSA), progression of pre-existing disease, or appearance of new metastases.

Prognosis is associated with several factors, including performance status, presence of bone pain, extent of disease on bone scan, and serum levels of alkaline phosphatase. Bone metastases will occur in 90% of men with hormone resistant prostate cancer and can produce significant morbidity, including pain, pathologic fractures, spinal cord compression, and bone marrow failure.

Xofigo's active ingredient, radium 223 dichloride (radium 223) is an alpha particle-emitting radioactive therapeutic agent which undermines the development and growth of tumors on bone metastases. The treatment is administered intravenously once per month for 6 months. Xofigo is the first and only alpha particle-emitting radioactive therapeutic agent approved by the FDA that has demonstrated improvement in overall survival and delay in time to first symptomatic skeletal event compared to placebo.  The new treatment emits low levels of alpha particle radiation, sparing and exposing little surrounding tissue due to small depth of penetration.

"Xofigo is an important new treatment added to our robust nuclear therapeutics program," says Benjamin Rosenbluth, MD, Director of Radiation Oncology at Holy Name Medical Center. "We provide the patients of Bergen County with leading-edge treatments for a broad range of cancers and are proud to play a significant role in the development and delivery of important new breakthrough treatments as part of Holy Name Medical Center," states Charles Vialotti, MD, Radiation Oncologist at Holy Name.

Xofigo has the advantages of enabling a better quality of life, pain relief, prolonged survival and fewer side effects for the appropriate men with castration resistant prostate cancer. According to Jacqueline Brunetti, MD, Director of Radiology at Holy Name, "Xofigo represents a significant advance in the current armamentarium of hormonal, chemotherapeutic and immunotherapy options available to men with castration-resistant prostate cancer.  Holy Name Medical Center, as the only facility in Bergen County to offer this new targeted therapy, is a clear demonstration of our commitment to providing cutting-edge therapies for our patients."

About the Regional Cancer Center at
Holy Name Medical Center

Holy Name Medical Center's Regional Cancer Center offers leading-edge diagnostic, staging and treatment for people with cancer. The Regional Cancer Center's outstanding team of board-certified specialists cares for patients in an environment that promotes personalized service and the patient's easy access to the multidisciplinary medical team. Medical and radiation oncologists, specialized surgeons, interventional radiologists, diagnostic radiologists and pathologists work together to ensure that every patient is armed with the best plan to fight cancer. Holy Name Medical Center's Regional Cancer Center is accredited by the American College of Radiology, the American Society for Radiation Oncology, and the American College of Surgeons Commission on Cancer as a Comprehensive Community Cancer Program—the patient's assurance of access to a broad spectrum of services, high quality patient care, safety and technical standards.

Holy Name Medical Center is a fully accredited, not-for-profit healthcare facility based in Teaneck, New Jersey, with off-site locations throughout Bergen County.  Founded and sponsored by the Sisters of St. Joseph of Peace in 1925, the comprehensive 361-bed medical center offers leading-edge medical practice and technology administered in an environment rooted in a tradition of compassion and respect for every patient. Holy Name provides high quality health care across a continuum that encompasses education, prevention, early intervention, comprehensive treatment options, rehabilitation and wellness maintenance—from pre-conception through end-of-life.

SOURCE Holy Name Medical Center