How Cell-Free mRNA Templates Support Faster Research with High-Quality and Quick Turnaround, Upcoming Webinar Hosted by Xtalks

In this free webinar, learn how integrated solutions — from vector design to cell-free in vitro transcription (IVT) template preparation — can streamline the production of high-quality mRNA templates and accelerate research outcomes. Attendees will understand the critical role of poly(A) tail integrity in IVT yield, mRNA stability and translational efficiency. The featured speaker will share how vector backbone design and poly(A) strategies influence plasmid propagation and mRNA performance. The speaker will compare different IVT template formats, including linearized plasmids and emerging cell-free synthesis methods. Attendees will discover essential quality control parameters, such as linearization, residual host DNA/protein removal and purity thresholds, that affect IVT success.

TORONTO, July 30, 2025 /PRNewswire/ -- mRNA has emerged as a powerful tool across vaccines, protein replacement therapies and gene editing. Central to these innovations is the need for ultra-fast, high-quality in vitro transcription (IVT) templates. Yet, researchers often face challenges in template preparation, from poly(A) tail instability, suboptimal template formats and designs to impurities that compromise mRNA quality and downstream applications.

In this webinar, the featured speaker will outline a comprehensive strategy for designing and preparing IVT-ready DNA templates, covering:

• Vector and backbone selection to support cloning, stable propagation and efficient linearization
• UTR and poly(A) tail design, including segmented poly(A) strategies that improve plasmid stability without sacrificing translational performance
• Comparison of IVT template formats, from plasmid-based linear templates to emerging cell-free synthesis methods
• Critical quality control parameters, including verification of linearization, removal of host-derived contaminants and purity thresholds that directly affect IVT outcomes
• Future directions in IVT template development, with a focus on scalable, automated and cell-free workflows that accelerate research timelines

In addition, the featured speaker will introduce GenScript's latest innovation, the Cell-Free IVT Template service, which delivers IVT-ready DNA starting from gene synthesis in as fast as six business days. This platform combines speed, purity and consistency to support efficient IVT and reliable mRNA output.

Whether focused on early discovery, high-throughput screening or translational research, this session will provide practical guidance to streamline mRNA workflows.

Register now to learn how integrated solutions — from vector design to cell-free IVT template preparation — can streamline the production of high-quality mRNA templates and accelerate research outcomes.

Join Andrew Tsao, Global Product Manager, GenScript, for the live webinar on Friday, August 22, 2025, at 1pm EDT (10am PDT).

For more information, or to register for this event, visit How Cell-Free mRNA Templates Support Faster Research with High-Quality and Quick Turnaround.

ABOUT XTALKS

Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars and digital content to the global life science, food, healthcare and medical device communities. Every year, thousands of industry practitioners (from pharmaceutical, biotechnology, food, healthcare and medical device companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps professionals stay current with industry developments, regulations and jobs. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

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Contact:
Vera Kovacevic
Tel: +1 (416) 977-6555 x371
Email: [email protected]

SOURCE Xtalks