HYDRINITY Advances Retinoid Innovation with RetaXome™ Daily Retinal Hydrator - The New Gold Standard in Dermatological Skincare

For the first time, RetaXome Daily Retinal Hydrator gives dermatologists and patients access to a powerful daily retinal that delivers superior results with unmatched tolerability.

NASHVILLE, Tenn., Sept. 8, 2025 /PRNewswire/ -- HYDRINITY, a leader in regenerative skin science, today announced the launch of RetaXome™ Daily Retinal Hydrator, the first and only daily-use retinal delivered by biomimetic exosome encapsulation technology. This breakthrough innovation delivers 10x the potency and faster results than traditional retinol—without the irritation, acclimation period, or redness—setting a new standard for dermatologists and patients.

"RetaXome is truly in a class of its own," said Dr. Michael Gold, board-certified dermatologist and lead clinical investigator. "We finally have a powerful retinal that delivers exceptional results with virtually no irritation, thanks to its biomimetic exosome delivery. It's a game-changer for patients seeking both performance and tolerability."

At the core of this innovation is the RetaXome Triple Action Therapy, a precision-engineered formula and delivery system designed to maximize efficacy and tolerability:

• Biomimetic Exosome Delivery System: Deep penetration down to the dermis for superior regeneration with high tolerability.
• Potent Retinal: Stabilized to deliver powerful yet gentle fast-acting results.
• Supercharged HA: Dual-weight, 100% injectable-grade hyaluronic acid delivers multi-layer hydration.

The proprietary biomimetic exosome is designed with Centella Asiatica bioactives and loaded with retinal, ensuring it mimics the cell communication needed to obtain deep dermal absorption, and optimal cell regeneration. This advanced delivery system is paired with barrier-strengthening Supercharged HA, ceramides, and an Adaptogenic Mushroom Complex for increased cellular turnover, hydration, barrier repair, and antioxidant protection in one single formula.

Key Benefits of RetaXome™ Daily Retinal Hydrator

• World's first and only retinal delivered by biomimetic exosome encapsulation technology
• 10x more potent and faster acting than traditional retinol
• No acclimation period — designed for nightly use from Day 1
• A powerful retinal formula that visibly reduces redness
• Clinically proven visible results in as little as 2 weeks

In a 12-week IRB-approved single-center clinical trial (20 female patients with mild to moderate fine lines, wrinkles, and photodamage), the investigator observed:

• 68% reduction in redness (erythema)
• 62% improvement in overall skin texture
• 55% improvement in skin tone
• 35% reduction in fine lines and wrinkles
• A statistically significant improvement in skin tone, texture, and fine lines as early as week 2 and improving through week 12

In a second multi-center, 20-subject open label study, patients reported:

At 2 weeks:

• 100% of patients experienced no irritation, burning, or inflammation
• 44% increase in measured hydration levels (via BIA digital Skin Analyzer)

At 4 weeks:

• 75% of patients reported visibly brighter, more even skin tone
• 65% of patients reported a visible reduction in brown spots and pigmentation

"With RetaXome, we've introduced the next generation of retinoid science," said Keith O'Briant, CEO of HYDRINITY Accelerated Skin Science. "Our new proprietary technology and formula represents a true category breakthrough, combining regenerative medicine with transformative performance to create a product that sets the new gold standard of what a retinal can achieve."

RetaXome™ Daily Retinal Hydrator is available now through our premier dermatologist and aesthetic professional partners and at hydrinity.com.

About HYDRINITY Accelerated Skin Science:
HYDRINITY Accelerated Skin Science, the fastest-growing professional skincare brand in the U.S. according to Kline + Company, is a leader in novel, patented, and proprietary regenerative technologies including Supercharged HA™, MicroFusion™, and RetaXome™. Founded as a regenerative medicine company developing advanced wound care and drug delivery systems for oncology and hematology patients, HYDRINITY has since redefined dermatological skincare with clinically backed formulations featuring injectable-grade hyaluronic acid and other breakthrough delivery platforms designed to deliver accelerated results and optimal skin health. Since launching in 2022, HYDRINITY has rapidly expanded into more than 4,000 professional U.S. practices and 30 countries globally, continuing to set new standards in skin regeneration. For more information, visit the brand on Facebook, Instagram, TikTok or at Hydrinity.com.

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Rebel Gail Communications | Jessica Goldberg

Contact: 
Jessica Goldberg
212.675.8555
[email protected]

SOURCE HYDRINITY Accelerated Skin Science