Knox Lane Partners with HCEsquared

Positions HCEsquared to Accelerate Growth Trajectory and Expand Operations

SAN FRANCISCO and VAIL, Colo., March 19, 2025 /PRNewswire/ -- Knox Lane, a growth-oriented investment firm, today announced a significant strategic investment in Healthcare Experts Squared ("HCEsquared" or the "Company"), a leading education, information and services platform serving healthcare professionals to ultimately elevate patient care. HCEsquared leadership will remain in their roles with management investing alongside Knox Lane. Terms of the transaction were not disclosed.

HCEsquared, the management company of Dermsquared and CMEsquared, was founded in 2001 with the mission of keeping the nation's top dermatologists connected to the latest diagnoses and most advanced treatments. The Company has established itself as a leader in the U.S. medical dermatology market. Serving over 90% of U.S. dermatology healthcare professionals with more than 100 industry partners, the Company is a trusted platform connecting the entire medical, aesthetic and surgical dermatology community.

Knox Lane's partnership will support the Company's growth across new services, geographies and specialties. HCEsquared is well-positioned to execute on its significant expansion opportunities in adjacent therapeutic areas, international markets and new market segments through a continued focus on innovation, digital and product development and strong industry relationships.

"We're thrilled to join forces with Knox Lane to build on our success and strengthen our leadership in serving health care professionals," said Eric Bruno, CEO of HCEsquared. "We are excited to have a partner who shares our core customer-centric values, and we look forward to benefitting from Knox Lane's deep sector and operational expertise as we continue to provide practical solutions for the biggest opportunities in dermatology and beyond. Together, we will bring our platform to an even higher level of excellence as we work to elevate patient care."

"We look forward to leveraging Knox Lane's experience to help take the Company to the next level, while maintaining HCEsquared's 25-year track record in serving the needs of healthcare professionals and their patients," said Darrell Rigel, MD, MS, Senior Clinical Advisor to HCEsquared, speaking on behalf of clinical advisors and medical directors, April Armstrong, MD, MPH, Mathew Avram, MD, JD, Jim Del Rosso, DO, Seemal Desai, MD, Linda Stein Gold, MD, Gary Goldenberg, MD, Mark Kaufmann, MD, Mark Lebwohl, MD, Lauren Miller, MPAS, PA-C and Mark Nestor, MD, PhD.

"We are excited to welcome HCEsquared to the Knox Lane family," said John Bailey, Managing Partner at Knox Lane, and Brent Gunderson, Managing Director at Knox Lane. "HCEsquared has a comprehensive product portfolio of integrated, market-leading solutions managed by an exceptional management team with a track record of success. The U.S. dermatology market is large and growing, and HCEsquared is well-positioned to address critical needs for healthcare professionals and expand across adjacent specialties, new segments and geographies. We look forward to leveraging our resources and experience to further advance the Company as a preeminent, differentiated dermatology services platform."

HCEsquared marks Knox Lane's fourth platform investment in the pharmaceutical and healthcare services sectors, building on recent investments in All Star Healthcare Solutions, Spectrum Science and Fingerpaint Group.

BrightTower LLC served as financial advisor and Shulman Rogers LLP acted as legal counsel to HCEsquared. Houlihan Lokey, Inc. served as financial advisor and Kirkland & Ellis LLP acted as legal counsel to Knox Lane.

About HCEsquared

Healthcare Experts Squared ("HCEsquared") is a leading management platform which drives enterprise support services across its portfolio of companies that are built by healthcare professionals for healthcare professionals. The Company finds innovative ways to maximize the value of the portfolio through scaled systems and services, strategic leadership, and acquisition opportunities. HCEsquared focuses on the management of companies providing services anchored in information services, insights and solutions, and medical education for professionals to elevate patient care. HCEsquared is currently focused on dermatology with CMEsquared providing accredited medical education and Dermsquared providing non-accredited education, information and services while also serving as a distribution channel for CMEsquared content. For more information, visit www.hcesquared.com.

About Knox Lane

Based in San Francisco, Knox Lane is a growth-oriented investment firm comprised of a team of accomplished investors and operators with a shared work history and a strong track record of partnering with leading companies to accelerate transformational growth. Knox Lane employs an investor-operator mindset and seeks to provide support across a number of business components, including human capital, brand management, end-to-end digital transformation, sourcing, supply chain and logistics, strategic acquisitions and business development. For more information, please visit www.knoxlane.com.

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SOURCE Knox Lane