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Male Menopause Affects More Than Five Million Men


News provided by

Northwestern Memorial Hospital

Aug 20, 2010, 11:24 ET

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Low testosterone levels to blame for low libido, fatigue and weight gain

CHICAGO, Aug. 20 /PRNewswire-USNewswire/ -- While most frequently associated with women's health, age-related hormone changes, often dubbed menopause, can occur in men as well, causing symptoms of fatigue, mood swings, decreased desire for sex, hair loss, lack of concentration and weight gain.  Experts estimate that more than 5 million men are affected, yet worry the number may be considerably higher since symptoms are frequently ignored.  

Male hypogonadism, as it's referred to in the medical community, occurs when the testicles do not produce enough testosterone, the hormone that plays a key role in masculine growth and development.  When hormone levels drop, men can experience significant mental and physical changes.  

"This is a highly prevalent disorder," said Robert Brannigan, MD, urologist at Northwestern Memorial Hospital.  "Unfortunately, we estimate that 95 percent of cases are undiagnosed and therefore untreated.  When ignored, symptoms can seriously disrupt one's quality of life."

"My body was telling me that something wasn't right.  I was always tired, it didn't matter how much sleep I got, I constantly wanted to take a nap," said Michael Andruzzi, a 40-year-old man diagnosed with male hypogonadism and a patient at Northwestern Memorial.  

Brannigan explains hormone variations are a normal aspect of getting older.  "In females, ovulation comes to an end and hormone production declines in a relatively quick period of time, whereas men experience hormone shifts more slowly, with testosterone levels dropping around one percent each year beginning in a man's late thirties," adds Brannigan, who is also an associate professor of urology at the Northwestern University Feinberg School of Medicine.

Brannigan goes on to explain that by age seventy, the reduction in a male's testosterone level could be as high as fifty percent or more compared to baseline levels, but notes that aging men are not the only ones at risk.  A number of genetic causes can impact males from birth and are usually diagnosed with failure to progress normally through puberty during the teenage years.  

Treatment options for male hypogonadism include hormone replacement therapy (HRT) via absorbable pellet implants, topical gels, patches, and injections.  Through HRT, doctors can restore sexual function and muscle strength.  In addition, men often experience an increase in energy and an improved overall sense of well-being.

"Once I began treatment, I felt better very quickly," said Andruzzi.  "My energy level shot back up; I regained strength and felt I could concentrate much better."

"We are seeing more men affected by male hypogonadism than we saw ten years ago," said Brannigan.  "However, many men continue to suffer in silence due to a lack of awareness surrounding the disorder.  Because male hypogonadism can significantly impact the quality of one's life, it's important that men pay attention to their body and openly discuss symptoms with their physician in order to prevent overlooking the cause and avoid missing an opportunity for appropriate therapy."

Although research to determine the exact association continues, doctors also warn that male hypogonadism has been linked to chronic medical conditions such as high cholesterol, diabetes and cardiovascular disease.  It's also closely associated with infertility.

"This disorder is not something that should be ignored," said Brannigan, who is working to educate patients and physicians about the symptoms and treatments available in order to ensure therapies are made available to men in need.  

Male hypogonadism is most commonly diagnosed through a simple blood test.  Brannigan notes hormone replacement therapy is not appropriate for all patients especially those with history of prostate and breast cancer and men trying to conceive.  He suggests consulting your doctor if you are experiencing symptoms.  

For more information or to schedule an appointment call 312-926-8400.  

About Northwestern Memorial HealthCare

Northwestern Memorial HealthCare is the parent corporation of Chicago's Northwestern Memorial Hospital, an 854-bed academic medical center hospital and Northwestern Lake Forest Hospital, a 215-bed community hospital located in Lake Forest, Illinois. 

About Northwestern Memorial Hospital

Northwestern Memorial Hospital is one of the country's premier academic medical centers and is the primary teaching hospital of the Northwestern University Feinberg School of Medicine.  Along with its Prentice Women's Hospital and Stone Institute of Psychiatry, the hospital comprises 854 beds, 1,603 affiliated physicians and 7,144 employees.  Northwestern Memorial is recognized for providing exemplary patient care and state-of-the art advancements in the areas of cardiovascular care; women's health; oncology; neurology and neurosurgery; solid organ and soft tissue transplants and orthopaedics.

Northwestern Memorial possesses nursing Magnet Status, the nation's highest recognition for patient care and nursing excellence, and it is listed in 12 clinical specialties in U.S. News & World Report's 2010 "America's Best Hospitals" guide. For 10 years running, it has been rated among the "100 Best Companies for Working Mothers" guide by Working Mother magazine. The hospital is a recipient of the prestigious National Quality Health Care Award and has been chosen by Chicagoans as the Consumer Choice according to the National Research Corporation's annual survey for 11 years.  

SOURCE Northwestern Memorial Hospital

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