Microbiome Clinical Trial Pipeline Space Brims with Novel Emerging Therapies with 130+ Key Players Working in the Domain | DelveInsight

Microbiome clinical trial pipeline constitutes 130+ key companies continuously working towards developing 200+ microbiome drugs, analyzes DelveInsight

LAS VEGAS, Nov. 9, 2022 /PRNewswire/ -- DelveInsight's 'Microbiome Competitive Landscape – 2022' report provides comprehensive global coverage of available, marketed, and pipeline microbiome drugs in various stages of clinical development, major pharmaceutical companies are working to advance the pipeline space and future growth potential of the microbiome competitive domain.

Key Takeaways from the Microbiome Pipeline Report

• Over 130+ microbiome companies are evaluating 200+ microbiome pipeline therapies in various stages of development, and their anticipated acceptance in the microbiome market would significantly increase market revenue. 
• Leading microbiome companies such as Evelo Biosciences, Vedanta Biosciences, MatriSys Biosystem, 4D Pharma, AOBiome, Caelus Health, DA Volterra, Debiopharm, Enterome Bioscience, Rebiotix, Finch Therapeutics Group, Igen Biotech Group, ImmuneBiotech, Precigen Inc, Immuron, Kaleido Biosciences, YSOPIA Bioscience, MaaT Pharma, Microbiome Therapeutics, MyBiotics, Naked Biome, Nubiyota, OxThera, Pylum Biosciences, Ritter Pharmaceuticals, Seres Therapeutics, Symberix, Symbiotix Biotherapies, Xycrobe Therapeutics, Boehringer Ingelheim, BSN Medical GmbH, GlaxoSmithKline, Pfizer, Summit Therapeutics, Institut Pasteur, MetaboGen AB, Johnson & Johnson, Access Business Group, Integrative Skin Science and Research, Verdure Sciences, Seraphic Group Inc, Viome, Sytheon Ltd., Mead Johnson Nutrition, VastBiome, Lei Li, FemTec Health Inc., General Mills, Biotax Labs LTD, HyGIeaCare, Inc., AceTech, Eisai Inc., RenovoDerm, Northwell Health, Napo Pharmaceuticals, Inc., Origimm Biotechnology GmbH, Freya Biosciences ApS, Igenomix, Ganeden Biotech, Inc., BioGaia AB, Ardigen, YUN NV, Persephone Biosciences, Biofortis, Merieux NutriSciences, Lonza Inc., Merck Sharp & Dohme LLC, Evolve BioSystems, Paratek Pharmaceuticals, Winclove Bio Industries BV, Mundipharma Manufacturing Pte Ltd., Bio-Strath AG, Clinical Nutrition Research Center, Illinois Institute of Technology, Igy Nutrition, Pathnostics, Thorne Research Inc., Danone Asia Pacific Holdings Pte, Ltd., NHS Tayside, Varian Medical Systems, Senda Biosciences, Rho Federal Systems Division, Inc., Nutricia, Inc., Ortho Dermatologics, Nestlé, and others are evaluating novel microbiome drugs candidate to improve the treatment landscape.
• Key Microbiome pipeline therapies in various stages of development include VE-202, MSB-01, Blautix, B244, MRx 518, Thetanix, ABI-M201, ABI-M301, AZT-04, CP 001, DAV 132, Debio 1453, Debio 1454, Debio 1454M, EB-8018, EDP 1503, RBX 2660, MaaT 013, MaaT 033, RBX 7455, FIN-525, FIN-524, Antibody-toxin conjugates, CP101, FIN-211, IMM-529 , IMM-124E, AG 019, AG017, KB 195, KB174, KB 109, Yso1, Yso 2, Yso3, Yso4, Yso5, MaaT 03X, MSB 3163, MSB 5710, MSB 2040, MSB 2179, MSB 6005, MSB 4249, SER-109, SER-155, SER 287, SER 301, and others.
• In October 2022, Seres Therapeutics' Biologics License Application (BLA) for SER-109, an investigational oral microbiome therapeutic for the prevention of recurrent Clostridium difficile infection (rCDI), was accepted for review by the FDA.
• On 20 October 2022, Summit Therapeutics Inc. and its product candidate, ridinilazole, had an oral podium presentation at IDWeek 2022.
• In July 2022, Tate & Lyle, a leading global provider of food and beverage ingredients and solutions, is delighted to announce that it is extending its partnership with APC Microbiome Ireland, a Science Foundation Ireland (SFI) Research Centre, through a new two-year research project to increase understanding of how dietary fibers can impact the functioning of the gut microbiome.
• In June 2022, Microbiome DX company Genetic Analysis AS ("GA") and Servatus Biopharmaceuticals Ltd ("Servatus"), have entered a Strategic Collaboration Agreement to combine their respective expertise to advance the microbiome diagnostics and therapeutics markets further. The collaboration will bring together Servatus' world-class knowledge of biotherapeutics and GA's microbiome diagnostic signature analysis to ultimately develop new diagnostic markers and treatment options to improve patients' lives worldwide.
• In May 2022, Gnubiotics Sciences SA (Gnubiotics) announced a strategic partnership agreement with ADM, a global leader in human and animal nutrition. The strategic partnership is centered on the commercialization of innovative microbiome solutions for companion animal health and wellbeing. This strategic partnership provides ADM with unique access to cutting-edge technologies and a pipeline of microbiome-focused innovation from Gnubiotics.
• In January 2022, BiomeBank, which has recently launched its Series-A funding round, has signed a four-year collaborative agreement with Hudson Institute to translate current and future microbiome research into microbial therapies. This includes a recent deal granting BiomeBank access to important research on how the microbiota could treat pediatric IBD, which is unique because the research used culturing and high-resolution microbial analysis of the colon rather than stool samples. The partnership strengthens Hudson Institute's business case for an Australian-first National Centre for Inflammation Research ("NCIR") and will initially focus on the development of defined and targeted microbial therapies to treat the unmet medical needs of patients with Inflammatory Bowel Disease ("IBD").

Request a sample and discover the recent advances in the microbiome therapeutics landscape @Microbiome Competitive Landscape Report

Microbiome Overview

The term "microbiome" refers to a grouping of microbes and their interactions with the human body. The microbiome is important in human physiology and disease. The interaction of microbes with the human body demonstrates various aspects of human biology. If the microbiome is well understood, it can be used to create personalized medicine tailored to the patient's needs.

As there are currently no approved microbiome drugs on the market, many companies are racing to develop new drugs or aiming to develop therapies that can alter the microbiome for the benefit of human health. Proper microbial flora monitoring has the potential for early disease diagnosis and can thus be used as a treatment strategy for conditions that have proven untreatable with conventional methods.

Find out more about bacteria in human microbiome @Human Microbiomes

Microbiome Pipeline Analysis: Drug Profile

B244: AOBiome

AOBiome's B244 is a patented, proprietary topical formulation containing a single live strain of Nitrosomonas eutropha D23, an ammonia-oxidizing bacteria (AOB). It metabolizes sweat ammonia to produce nitrite and nitric oxide, both of which have anti-inflammatory and anti-infective properties. The therapeutic drug was created to repopulate the skin microbiome with AOBs, which are naturally present in the body but are removed by most soaps.

Blautix: 4D Pharma

4D Pharma is developing Blautix, an orally administered drug. The drug is in Phase II development for the treatment of irritable bowel syndrome (IBD). Blautix is a single-strain human gut commensal bacterium with a unique metabolism that may be used to treat IBS. Blautix consumes gases in the gut that are known to cause bloating, abdominal pain, and changes in bowel frequency. The company completed a successful Phase Ib clinical study of Blautix in IBS patients, and the results were encouraging, according to the company, and provided a solid foundation for moving Blautix into larger clinical studies and further evaluation as a potential treatment for IBS.

A snapshot of the Microbiome Pipeline Drugs mentioned in the report:

Learn more about the microbiome drug development @Microbiome Clinical Trials

Scope of the Microbiome Competitive Landscape Report 

• Coverage: Global 
• Key Microbiome Companies: Evelo Biosciences, Vedanta Biosciences, MatriSys Biosystem, 4D Pharma, AOBiome, Caelus Health, DA Volterra, Debiopharm, Enterome Bioscience, Rebiotix, Finch Therapeutics Group, Igen Biotech Group, ImmuneBiotech, Precigen Inc, Immuron, Kaleido Biosciences, YSOPIA Bioscience, MaaT Pharma, Microbiome Therapeutics, MyBiotics, Naked Biome, Nubiyota, OxThera, Pylum Biosciences, Ritter Pharmaceuticals, Seres Therapeutics, Symberix, Symbiotix Biotherapies, Xycrobe Therapeutics, Boehringer Ingelheim, BSN Medical GmbH, GlaxoSmithKline, Pfizer, Summit Therapeutics, Institut Pasteur, MetaboGen AB, Johnson & Johnson, Access Business Group, Integrative Skin Science and Research, Verdure Sciences, Seraphic Group Inc, Viome, Sytheon Ltd., Mead Johnson Nutrition, VastBiome, Lei Li, FemTec Health Inc., General Mills, Biotax Labs LTD, HyGIeaCare, Inc., AceTech, Eisai Inc., RenovoDerm, Northwell Health, Napo Pharmaceuticals, Inc., Origimm Biotechnology GmbH, Freya Biosciences ApS, Igenomix, Ganeden Biotech, Inc., BioGaia AB, Ardigen, YUN NV, Persephone Biosciences, Biofortis, Merieux NutriSciences, Lonza Inc., Merck Sharp & Dohme LLC, Evolve BioSystems, Paratek Pharmaceuticals, Winclove Bio Industries BV, Mundipharma Manufacturing Pte Ltd., Bio-Strath AG, Clinical Nutrition Research Center, Illinois Institute of Technology, Igy Nutrition, Pathnostics, Thorne Research Inc., Danone Asia Pacific Holdings Pte, Ltd., NHS Tayside, Varian Medical Systems, Senda Biosciences, Rho Federal Systems Division, Inc., Nutricia, Inc., Ortho Dermatologics, Nestlé, and others
• Key Microbiome Pipeline Therapies: VE-202, MSB-01, Blautix, B244, MRx 518, Thetanix, ABI-M201, ABI-M301, AZT-04, CP 001, DAV 132, Debio 1453, Debio 1454, Debio 1454M, EB-8018, EDP 1503, RBX 2660, MaaT 013, MaaT 033, RBX 7455, FIN-525, FIN-524, Antibody-toxin conjugates, CP101, FIN-211, IMM-529 , IMM-124E, AG 019, AG017, KB 195, KB174, KB 109, Yso1, Yso 2, Yso3, Yso4, Yso5, MaaT 03X, MSB 3163, MSB 5710, MSB 2040, MSB 2179, MSB 6005, MSB 4249, SER-109, SER-155, SER 287, SER 301, and others.

Dive deep for rich insights into microbiome therapeutics; visit @Best Microbiome Supplements

Table of Contents

For further information on the microbiome analysis, reach out @Microbiome Research

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