New lab testing option for GI disorders.
DEERFIELD BEACH, Fla., May 21, 2014 /PRNewswire/ -- Distinguishing the cause of gut disorders can be complicated. Therefore, Cell Science Systems, Corp. today announced the launch of a new test to help clinicians reach a diagnosis; and, suggest dietary strategies to improve whatever gut malady a person may have. The Gut Health Profile or, GHP, is a blood test profile that evaluates GI health and risks on a genetic, antibody and cellular level. The GHP may be of use to physicians in determining risk of celiac and other GI conditions as well as identifying disease triggering foods other than gluten.
Understanding celiac disease and non-celiac gluten sensitivity
Celiac disease affects about 1% of the population. However, some experts believe the disease is underdiagnosed. Moreover, non-celiac gluten sensitivity, which may present symptoms similar to celiac disease are believed to be a much larger problem.
Dr. Alessio Fasano, a celiac researcher from Harvard, has identified a link between gluten intolerance and various non celiac gastrointestinal problems; including diarrhea, bloating, and indigestion; which could, under the right circumstance and with the right co-factors, progress to full blown celiac. Dr Fasano States, "Celiac disease and gluten sensitivity are subsets of gluten intolerance. Anyone who has celiac disease or gluten sensitivity is, by definition, gluten intolerant." Dr. Fasano concludes that sensitivity to gluten exists on a spectrum, from some people who are terribly sensitive as with celiac disease, to others who have no sensitivity at all — a spectrum that includes many, many people at every point in between. The Gut Health Panel is designed to help clarify where someone is on the spectrum
About the Gut Health Profile (GHP)
The genetic testing portion of the profile determines the genetic predisposition necessary for developing celiac. In order to develop celiac disease, a person must have one or both of two genetic factors; HLA-DQ2.5 and HLA-DQ8. This test has very high negative predictability; meaning, that if you don't have either or both of those genetic factors the chances of developing celiac are slim to none. It helps to alleviate concern if one tests negative.
The GHP's antibody analysis indicates, quantitatively, whether specific protective antibodies (secretory IgA) are deficient; or, if others types of antibodies, indicative of disease, are present. This analysis can help the physician differentiate between celiac, ulcerative colitis, and Crohn's disease, all of which may present with similar symptoms.
The ALCAT test for food and chemical sensitivity and intolerance portion of the test may help identify grains, including gluten containing grains, and others, as well as other foods that are causing an inflammatory cellular reaction and should therefore be considered for avoidance.
Last week researchers from Yale School of Medicine, who are studying the Alcat test, reported at the International Research Conference on Integrative Medicine, in Miami, early findings showing a clear cut association between Alcat test results and activation of other well-known inflammatory pathways. With their continued research efforts the medical profession may come closer to understanding more of the biochemical pathways linking food intolerance and various GI disorders. Yale researchers will also be commencing next month a clinical trial evaluating the benefits of an Alcat based diet on Irritable Bowel Syndrome patients.
For more information about the Gut Health Profile (GHP) visit www.alcat.com/pages/ghp-what-is-it/.
About Cell Science Systems
Cell Science Systems (www.alcat.com) is a specialty clinical laboratory that develops and performs laboratory testing in immunology, cell biology, molecular diagnostics, and other specialties supporting the personalized treatment and prevention of chronic disease. Cell Science Systems, Corp. operates a CLIA certified laboratory and is a FDA inspected registered, cGMP medical device manufacturer meeting ISO EN13485 standards. Cell Science Systems is best known for pioneering the Alcat Test for food and chemical sensitivities. The company operates subsidiaries in Europe and Asia.
*This press release is not intended to imply any endorsement from Dr. Alessio Fasano or the Center for Celiac Research at Harvard University or the Yale School of Medicine.
SOURCE Cell Science Systems
Share this article