New Published Research Study Confirms Effectiveness Of Novel Sensitive Toothpaste
DALLAS, Sept. 1, 2015 /PRNewswire/ -- Participants in a clinical study of a new toothpaste for sensitive teeth reported significant relief after just two days, according to a recent paper published in The Open Dentistry Journal http://benthamopen.com/FULLTEXT/TODENTJ-9-92. About half the participants claimed a significant reduction in their pain after 48 hours. At the end of two weeks, about three-quarters of the patients reported significant pain relief.
The study, "Reduction in Dental Hypersensitivity with Nano-Hydroxyapatite, Potassium Nitrate, Sodium Monofluorophosphate and Antioxidants," concluded that the toothpaste "applied daily significantly decreased tooth pain of dentin hypersensitivity within a two-day and a two-week time period."
Dentin hypersensitivity (DH) is a short, sharp tooth pain caused by cold or heat, sweets, or touch, that affects approximately 85 percent of the population. Before trying professional treatments for DH, most dentists recommend over-the-counter toothpaste. According to Samuel B. Low, DDS, MS, MEd, the lead researcher in the study, "Typically, so-called sensitive toothpastes, which contain potassium nitrate or sodium monofluorophosphate take several weeks before the patient feels any relief. Shortening that time before a patient feels relief is a momentous breakthrough."
About 60 patients participated in the study. One unique aspect of this study is that participation was restricted to patients who had tried commercial toothpastes designed for sensitivity without success. Most of the patients had DH due to an exposed tooth root. Other causes included sensitivity due to teeth whitening or unknown causes. Participants were given the sensitive formula toothpaste and instructed how to use it in their daily oral hygiene regimen. They were also instructed not to use any other toothpaste or treatment during the two-week study period.
To measure the effects of the toothpaste, the participants filled out a questionnaire that rated the degree of their tooth pain, its duration, its intensity and its tolerability at the initiation of the study, after two days of using the toothpaste, and again at the end of two weeks. The researchers gathered and analyzed the data and validated the significance of the results.
Edward P. Allen, DDS, PhD, a periodontist and co-author of the study, believes that the rapid effectiveness of the new toothpaste used in the study may be due in part to an ingredient called nano-hydroxyapatite. "It's a calcium-based compound found in the natural tooth structure that actually seems to replace some of the minerals in the enamel and dentin," says Allen. "The other ingredients in the toothpaste, monofluorophosphate and potassium nitrate, are routinely used in 'sensitive' toothpastes. However, most patients require at least one week to feel any difference in their pain."
The study also suggests that the antioxidants phloretin, ferulic acid and silymarin in this formula may further contribute to the rapid effectiveness of the test toothpaste. Additional research is planned to pinpoint the biochemical reasons why.
The toothpaste used in the study and marketed as SENSITIVE AO ProToothpaste by PerioSciences, is available through dental professionals. To learn more about PerioSciences please visit www.periosciences.com or call 800.915.8110.
The study was supported in part by Dallas-based PerioSciences LLC, which conducts ongoing scientific research on the effectiveness of topical antioxidants in oral care.
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SOURCE PerioSciences
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