New Study: Prunes Have Promising Effect on Men's Bone Health, Adding to Growing Body of Research

ROSEVILLE, Calif., Nov. 29, 2021 /PRNewswire/ -- New research from San Diego State University's School of Exercise and Nutritional Sciences reports that eating prunes daily has a protective effect on bone health in men over 50. This study is the first of its kind to examine the beneficial prune effect on bones in men. It is estimated that 2 million men are battling osteoporosis and another 16.1 million men have low bone mass, or osteopenia (Wright et al., 2014). Despite these statistics, bone disease in men is often overlooked.

"We've already seen significant evidence that prunes have a positive effect on bone health in women, so it's particularly exciting to find that prunes can also play a beneficial role in men's bone health. We look forward to continuing to study the 'prune effect' on bone and other health outcomes in men," said lead researcher Professor Shirin Hooshmand, PhD, RD, School of Exercise and Nutritional Sciences, San Diego State University.

In this randomized-controlled clinical study, 57 healthy men aged 50-79 years old were assigned to either consume 100 grams of prunes every day or no prunes for twelve months. At the conclusion of 1-year, the prune consumers showed significant decreases in biomarkers of bone breakdown, while no changes were observed in the control group (Hooshmand et al., 2021). The study authors also reported the men who ate prunes showed improvements in bone geometry indicating greater bone strength.

Historically, research has focused on osteoporosis and bone health in women, already indicating a favorable bone response to prunes specifically among postmenopausal women. Several studies have suggested that eating 50 to 100 grams of prunes everyday could lead to increased bone mass and decreased bone breakdown (Arjmandi et al., 2001; Hooshmand et al., 2011, 2014, 2016). Moreover, a recent case study published in the Bone Reports earlier this year reported that total bone mineral density increased in a postmenopausal woman with osteopenia after she consumed 50 grams of prunes daily for 16 months (Strock et al., 2021).

"Bone health is not just a concern for women. Men need to think about how to protect their bones as well," said Leslie Bonci, MPH, RDN and consultant with the California Prune Board. "Prunes are a shelf-stable and nutrient-packed food that provide a preventive, proactive, palatable option for men to optimize their bone health."

While San Diego State University's newest research is an exciting addition to existing prune-focused literature, more investigations into the effect of prunes on human bone health are currently underway. An upcoming study from Pennsylvania State University examines how consuming different amounts of prunes affects health outcomes in postmenopausal women over a one-year period. The study not only explores the impact of prunes on bone health, but it will also look at the prune-effect on inflammation and gut health.

The men's bone study by Hooshmand et al. (2021) can be found here.

FUNDING
The Journal of Medicinal Food study was funded by the San Diego State University Grant Program and the California Prune Board (No. 57114A; ClinicalTrials.gov, No. NCT02325895).

The Bone Reports study was funded by the California Prune Board.

REFERENCES

Wright, N. C., Looker, A. C., Saag, K. G., Curtis, J. R., Delzell, E. S., Randall, S., & Dawson-Hughes, B. (2014). The recent prevalence of osteoporosis and low bone mass in the United States based on bone mineral density at the femoral neck or lumbar spine. Journal of one and mineral research: the official journal of the American Society for Bone and Mineral Research, 29(11), 2520–2526. https://doi.org/10.1002/jbmr.2269

Hooshmand, S., Gaffen, D., Eisner, A., Fajardo, J., Payton, M., & Kern, M. (2021). Effects of 12 Months Consumption of 100 g Dried Plum (Prunes) on Bone Biomarkers, Density, and Strength in Men. Journal of Medicinal Food, 10.1089/jmf.2021.0080. Advance online publication. https://doi.org/10.1089/jmf.2021.0080

Arjmandi B. H. (2001). The role of phytoestrogens in the prevention and treatment of osteoporosis in ovarian hormone deficiency. Journal of the American College of Nutrition, 20(5 Suppl), 398S–420S. https://doi.org/10.1080/07315724.2001.10719175

Hooshmand, S., Chai, S. C., Saadat, R. L., Payton, M. E., Brummel-Smith, K., & Arjmandi, B. H. (2011). Comparative effects of dried plum and dried apple on bone in postmenopausal women. The British journal of nutrition, 106(6), 923–930. https://doi.org/10.1017/S000711451100119X.  

Hooshmand, S., Brisco, J. R., & Arjmandi, B. H. (2014). The effect of dried plum on serum levels of receptor activator of NF-κB ligand, osteoprotegerin and sclerostin in osteopenic postmenopausal women: a randomised controlled trial. The British journal of nutrition, 112(1), 55–60. https://doi.org/10.1017/S0007114514000671

Hooshmand, S., Kern, M., Metti, D., Shamloufard, P., Chai, S. C., Johnson, S. A., Payton, M. E., & Arjmandi, B. H. (2016). The effect of two doses of dried plum on bone density and bone biomarkers in osteopenic postmenopausal women: a randomized, controlled trial. Osteoporosis international: a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 27(7), 2271–2279. https://doi.org/10.1007/s00198-016-3524-8

Strock, N., Koltun, K. J., Weaver, C., & De Souza, M. J. (2021). Dried plum consumption improves bone mineral density in osteopenic postmenopausal woman: A case report. Bone reports, 14, 101094. https://doi.org/10.1016/j.bonr.2021.101094

ABOUT THE CALIFORNIA PRUNE BOARD
Created in 1952, The California Prune Board aims to amplify the premium positioning and top-of-mind awareness of California Prunes through advertising, public relations, promotion, nutrition research, crop management and sustainability research, and issues management. The California Prune Board represents approximately 800 prune growers and 28 prune, juice, and ingredient handlers under the authority of the California Secretary of Food and Agriculture.

SOURCE California Prune Board