NNB Nutrition Showcased Next-Generation Sweeteners, Naturally Occurring Dipeptides, Ultra-Pure Creatine and Fermented Actives at SupplySide Global 2026

Ingredient innovator launched SweetVantage® with stevia Reb M9 and brazzein and the VasoRush™ dipeptide complex, and showcased its latest innovations in dipeptides, fermentation and ingredient purification in Las Vegas

BOISE, Idaho, Nov. 4, 2026 /PRNewswire/ -- NNB Nutrition, the ingredient company behind the tagline "Pure. Potent. Precise Ingredients," showcased its latest innovations at SupplySide Global 2026, held October 28–30 at Mandalay Bay in Las Vegas. At Booth #5952, the NNB team met with formulators, brand owners and media across four areas of innovation: natural sweetener technology, dipeptide-based performance ingredients, ultra-pure creatine, and fermentation-derived actives for longevity and cognition.

"The conversations at SupplySide confirmed what we've been hearing all year. More brands are moving into the functional food space and creating what we call ready-to-consume supplementation: drinks, snacks, gummies and more. They're looking not only for clean ingredients, but for low-dose, high-potency ingredients as well. With our fermentation technology, we can satisfy both of those needs," said Dustin Elliott, Chief Brand Officer, NNB Nutrition USA.

Sweetener innovation: SweetVantage® and SweetVantage®+ with brazzein

SweetVantage® is a fermented steviol glycoside blend that now features NNB's patented stevia Reb M9, the result of three years and $2.5 million in research. It is designed to target the front, middle and back of the palate for a rounder, more sugar-like sweetness, with lower astringency than other natural sweeteners and a lower cost than stevia Reb M. In a research panel, stevia Reb M9 performed closest to sugar versus other natural sweeteners, and the entire blend can be labeled simply as "Steviol Glycosides."

SweetVantage®+ takes the platform further by adding brazzein, a fermented, sweet, non-caloric protein. The patent-pending combination of stevia Reb M9 and brazzein is designed for bitterness masking and enhanced sweetness perception, giving formulators a natural option for hard-to-flavor products such as EAAs, herbal extracts, protein, greens and complex sports formulas — applications that have traditionally relied on sucralose or bitter blockers. NNB can tailor the brazzein ratio to each formula's sweetness and bitter-blocking needs.

Dipeptide innovation: VasoRush™ and DL 185®

Dipeptides are pairs of amino acids bonded together with a peptide bond. Both of NNB's dipeptide ingredients occur in nature.

VasoRush™ is a 2:1 di-citrulline + di-arginine peptide complex designed to rethink nitric oxide delivery by focusing on vasodilation efficiency through cGMP, the signaling molecule that drives vascular relaxation. These dipeptides occur naturally in peptide structures found in food and human biology, and qualify as legal dietary ingredients that do not require new regulatory registrations. In the EU, a legal assessment concluded that di-arginine and di-citrulline should not be classified as novel foods. In NNB's in-house pre-clinical testing at a human-equivalent dose of 2.7 g/day, VasoRush™ increased plasma cGMP by 85%, kept nitric oxide elevated for up to six hours, and increased running time to exhaustion by 15.9% versus exercise control, outperforming higher 8 g doses of citrulline, citrulline malate and arginine.

DL 185® is dileucine (L-Leucyl-L-Leucine), two L-leucine molecules enzymatically bonded together. DL 185® is naturally occurring in protein foods, but at very low levels: it would take 159 g of whey protein concentrate or 219 g of pea protein to equal a single 2 g serving. In human research, 2 g of DL 185® delivered 86% more leucine to muscles within 30 minutes and a 60% greater increase in muscle protein synthesis compared with the same amount of leucine (Paulussen et al., 2021), and supported strength gains compared with placebo in a multi-week training study (Hagele et al., 2024). DL 185® is patented and available exclusively from NNB Nutrition.

The world's purest creatine: Pürest Creatine™

Pürest Creatine™ is NNB's answer to quality shortcuts in creatine manufacturing. Produced through a proprietary synthesis method that avoids reaction pathways that create hazardous byproducts, it delivers the industry's lowest levels of DCD, DHT and creatinine, verified through third-party testing, with less than 1.0 ppm of each heavy metal. Every lot is tested for major contaminants using a validated method with Eurofins to detect previously undetectable levels of DCD and DHT. Every lot is tested for impurities with retain samples held. Pürest Creatine™ is vegan, allergen-free,non-GMO, Informed Choice and is priced at nearly half the cost of other high-purity creatines.

It also recently won an award at Health Ingredients & Food Ingredients Asia-China (Hi & Fi Asia-China). The Greater Bay Area Selected Healthy Ingredients Gold Award recognized its exceptional purity standards and revolutionary manufacturing process.

Fermented ingredients: MitoPrime® and SalidroPure™

MitoPrime® is a pure L-isomer of L-ergothioneine produced through a patented natural fermentation process. It would take 20 g of fresh king oyster mushroom to reach an active dose of MitoPrime®. Compared with extracted ergothioneine, the fermentation process requires less biomass, uses no harsh solvents and carries a lower carbon footprint. MitoPrime® is self-affirmed GRAS, and in human research a 20 mg dose produced a 2.3x increase in plasma ergothioneine and improvements in subjective sleep quality (Okumura et al., 2025). It is positioned for longevity, mitochondrial, cognitive and recovery formulas.

SalidroPure™ is pure, fermented, non-GMO salidroside — one of the key active compounds in Rhodiola rosea. With Rhodiola now subject to international trade restrictions under CITES, high-concentration extracts have become harder to source. SalidroPure™ offers a sustainable alternative: a 20–30 mg dose provides the salidroside found in roughly 2,000 mg of Rhodiola rosea, in a format small enough for gummies, smaller capsules and dissolving strips. SalidroPure™ is self-affirmed GRAS up to 87.2 mg and is designed for nootropic, adaptogen, mood and stimulant-free energy formulas.

Ready to consume: the OnSwitch concept drink

NNB also brought the ready-to-consume trend to life at its booth with OnSwitch, a ready-to-drink concept beverage formulated to go beyond caffeine. OnSwitch combines NNB's fermentation-derived, low-dose actives, including MitoPrime® fermented L-ergothioneine and SalidroPure™ fermented salidroside, with [confirm full ingredient list, e.g., enfinity® paraxanthine, GeniusPure® Alpha-GPC and MitoBurn® L-BAIBA] to support energy, focus and resilience. The concept showed brands how NNB ingredients can move beyond capsules and powders into drinks and other functional food formats.

Continue the conversation

Formulators and brand owners who missed NNB at SupplySide Global, or who want to follow up on a conversation from the show, can request samples, technical data or a meeting at info@nnbnutrition.com.

About NNB Nutrition

NNB Nutrition develops science-backed, patented and fermentation-derived ingredients for the dietary supplement, sports nutrition and functional food and beverage industries. Learn more at www.nnbnutrition.com.

Media contact: Dustin Elliott, dustin@nnbusa.com

NNB Nutrition provides ingredient information as a resource for claim development. Brands are responsible for ensuring their finished-product claims are substantiated and compliant with applicable regulations.

SOURCE NNB Nutrition