PRN's Omega-3 Hits Major Endpoints Against Placebo in a Study of Dry Eye Symptoms

Apr 17, 2015, 09:00 ET from ALPHAEON Corporation

IRVINE, Calif., April 17, 2015 /PRNewswire/ -- ALPHAEON Corporation and its subsidiary company PRN Physician Recommended Nutriceuticals, a leading provider of nutritional supplements, announced today the upcoming presentation of a new study assessing the effect of oral re-esterified triglyceride omega-3 fatty acids for patients with dry eye symptoms and meibomian gland dysfunction. Findings from the study will be presented at the American Society of Cataract and Refractive Surgery (ASCRS) conference on April 19, 2015 at 8:00 AM, by Dr. Eric Donnenfeld a clinical professor of ophthalmology at New York University and immediate past president of ASCRS.   

"Oral omega 3 supplementation is one of the foundations for the management of meibomian gland dysfunction and dry eye symptoms," said Dr. Donnenfeld. "The advantage of using a re-esterified triglyceride omega-3 fatty acid such as the one produced by PRN, which was studied in the trial, is that the omega-3 maintains its natural triglyceride structure which can be easily metabolized and absorbed.  Greater bioavailability translates into greater physiological value. In the study, PRN omega-3 supplementation achieved significant improvement in dry eye signs and symptoms versus placebo over a 12-week course that is superior to any study previously published, and I look forward to sharing the details of this important trial at the American Society of Cataract and Refractive Surgery."

The placebo controlled, double masked, randomized trial measured various endpoints including tear osmolarity, ocular surface disease index, tear break-up time, corneal staining and omega-3 index levels.  During the trial, subjects received PRN Dry Eye Omega Benefits® supplement for three months or a placebo. The study demonstrated that oral consumption of re-esterified triglyceride omega-3 fatty acids results in a statistically significant improvement in many of the above endpoints measured.

Edward Holland, MD, Cincinnati Eye Institute, who served as an investigator on the study stated, "The results from this study should be revealing for any ophthalmologist with dry eye patients, especially the fact that PRN's omega-3 showed significant improvement in not just one, but multiple endpoints, including tear osmolarity and tear break-up time. This data demonstrates that re-esterified triglyceride omega-3 fatty acid supplementation is an important option for patients with dry eye symptoms."

The study abstract can be viewed on the ASCRS website at the following URL:

About ALPHAEON Corporation
ALPHAEON Corporation is the first social commerce company transforming self-pay healthcare by bringing to market highly innovative products and services to promote consumer wellness, beauty and performance.  The company works in partnership with board certified physicians ensuring access to leading advancements in lifestyle healthcare.  For more information, please visit

About PRN Physician Recommended Nutriceuticals
PRN is a leading developer of omega-3 products and nutritional supplements.  Developed by doctors and recommended by world-renowned medical thought leaders, PRN's products are supported by medical evidence and offer exceptional quality and purity. PRN was recently acknowledged on the Inc. 500|5000 list of fastest growing privately held companies. PRN is a subsidiary of ALPHAEON Corporation. 


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