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Reportlinker Adds Gastrointestinal Stromal Tumors (GIST) Therapeutics - Pipeline Assessment and Market Forecasts to 2017


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Reportlinker

Apr 14, 2011, 06:32 ET

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NEW YORK, April 14, 2011 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

Gastrointestinal Stromal Tumors (GIST) Therapeutics - Pipeline Assessment and Market Forecasts to 2017

http://www.reportlinker.com/p0479823/Gastrointestinal-Stromal-Tumors-GIST-Therapeutics---Pipeline-Assessment-and-Market-Forecasts-to-2017.html

Gastrointestinal Stromal Tumors (GIST) Therapeutics - Pipeline Assessment and Market Forecasts to 2017

Summary

GlobalData, the industry analysis specialist, has released its new report, "Gastrointestinal Stromal Tumors (GIST) Therapeutics - Pipeline Assessment and Market Forecasts to 2017". The report is an essential source of information and analysis on the global Gastrointestinal Stromal Tumors market. The report identifies the key trends shaping and driving the global Gastrointestinal Stromal Tumors market. The report also provides insights on the prevalent competitive landscape and the emerging players expected to significantly alter the market positioning of the current market leaders. Most importantly, the report provides valuable insights on the pipeline products within the global Gastrointestinal Stromal Tumors sector. This report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GlobalData's team of industry experts.

Scope

The report provides information on the key drivers and challenges of the Gastrointestinal Stromal Tumors market. Its Scope includes -

- Annualized seven key markets (US, France, Germany, Italy, Spain, UK and Japan) Gastrointestinal Stromal Tumors market revenues data from 2005 to 2009, forecast for eight years to 2017.

- Pipeline analysis data providing a split across the different phases, mechanisms of action being developed and emerging trends by seven key markets. Pipeline candidates fall under major therapeutic classes.

- Analysis of the current and future competition in the seven key countries Gastrointestinal Stromal Tumors market.

- Insightful review of the key industry drivers, restraints and challenges. Each trend is independently researched to provide a qualitative analysis of its implications.

- Key topics covered include strategic competitor assessment, market characterization, unmet needs and the implications for the Gastrointestinal Stromal Tumors therapeutics market.

- Analysis of key recent licensing and partnership agreements in gastrointestinal stromal tumors market

Reasons to buy

The report will enhance your decision making capability. It will allow you to -

- Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies and by identifying the companies with the most robust pipeline.

- Develop business strategies by understanding the trends shaping and driving the global Gastrointestinal Stromal Tumors market.

- Drive revenues by understanding the key trends, innovative products and technologies, market segments and companies likely to impact the global Gastrointestinal Stromal Tumors market in future.

- Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.

- Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.

- Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.

- What's the next big thing in the global Gastrointestinal Stromal Tumors market landscape? – Identify, understand and capitalize.

1 Table of contents

1 Table of contents 2

1.1 List of Tables 4

1.2 List of Figures 5

2 Gastrointestinal Stromal Tumor (GIST) Therapeutics: Introduction 6

2.1 Overview 6

2.2 Epidemiology 6

2.3 Symptoms 7

2.4 Etiology 7

2.5 Staging of GIST 8

2.6 Diagnosis of GIST 9

2.6.1 Computed Tomography Scan (CT scan) 9

2.6.2 X-ray 9

2.6.3 Magnetic Resonance Imaging (MRI) or Positron Emission Tomography (PET scan) 9

2.6.4 Mutational Analysis 9

2.7 Treatment of GIST 9

2.7.1 Surgery 9

2.7.2 Radiation Therapy 10

2.7.3 Chemotherapy 10

2.7.4 Targeted Therapy 10

2.8 GlobalData Pipeline Report Guidance 11

3 Gastrointestinal Stromal Tumor (GIST) Therapeutics: Market Characterization 12

3.1 GIST Therapeutics Market Size (2005-2010) – Global 12

3.2 GIST Therapeutics Market Forecast (2010-2017) – Global 13

3.3 GIST Therapeutics Market Size (2005-2010) – The US 14

3.4 GIST Therapeutics Market Forecast (2010-2017) – The US 15

3.5 GIST Therapeutics Market Size (2005-2010) – France 16

3.6 GIST Therapeutics Market Forecast (2010-2017) – France 17

3.7 GIST Therapeutics Market Size (2005-2010) – Germany 18

3.8 GIST Therapeutics Market Forecast (2010-2017) – Germany 19

3.9 GIST Therapeutics Market Size (2005-2010) – Italy 20

3.10 GIST Therapeutics Market Forecast (2010-2017) – Italy 21

3.11 GIST Therapeutics Market Size (2005-2010) – Spain 22

3.12 GIST Therapeutics Market Forecast (2010-2017) – Spain 23

3.13 GIST Therapeutics Market Size (2005-2010) – The UK 24

3.14 GIST Therapeutics Market Forecast (2010-2017) – The UK 25

3.15 GIST Therapeutics Market Size (2005-2010) – Japan 26

3.16 GIST Therapeutics Market Forecast (2010-2017) – Japan 27

3.17 Drivers and Barriers for the GIST Therapeutics Market 28

3.17.1 Drivers for the GIST Therapeutics Market 28

3.17.2 Barriers for the GIST Therapeutics Market 28

3.18 Opportunity and Unmet Need Analysis 29

3.19 Key Takeaway 30

4 Gastrointestinal Stromal Tumor (GIST) Therapeutics: Competitive Assessment 31

4.1 Overview 31

4.2 Strategic Competitor Assessment 31

4.3 Product Profiles for the Major Marketed Products in the GIST Therapeutics Market 32

4.3.1 Gleevec (imatinib mesylate) 32

4.3.2 Sutent (sunitinib malate) 35

4.4 Key Takeaway 36

5 Gastrointestinal Stromal Tumor (GIST) Therapeutics: Pipeline Assessment 37

5.1 Overview 37

5.2 Strategic Pipeline Assessment 37

5.3 GIST Therapeutics Pipeline – Pipeline by Phases of Development 37

5.3.1 GIST Therapeutics – Phase III Pipeline 37

5.3.2 GIST Therapeutics – Phase II Pipeline 38

5.3.3 GIST Therapeutics – Phase I Pipeline 38

5.3.4 GIST Therapeutics – Preclinical Pipeline 38

5.3.5 Technology Trends Analytic Framework 39

5.4 GIST Therapeutics – Pipeline by Mechanism of Action 41

5.5 Molecule Profile for Promising Drugs Under Clinical Development 42

5.5.1 Masitinib 42

5.5.2 Tasigna (Nilotinib) 42

5.5.3 Nexavar (Sorafenib) 43

5.5.4 Regorafenib (BAY 73-4506) 44

5.6 Key Takeaway 45

6 Gastrointestinal Stromal Tumor (GIST) Therapeutics: Clinical Trials Mapping 46

6.1 Clinical Trials by Country (US, EU5 and Japan) 46

6.2 Clinical Trials by Phase 47

6.3 Clinical Trials by Trial Status 48

6.4 Prominent Sponsors 49

6.5 Top Companies Participating in GIST Therapeutics Clinical Trials 51

7 Gastrointestinal Stromal Tumor (GIST) Therapeutics: Strategic Assessment 52

7.1 Key Events Impacting the Future Market 52

7.2 GIST Therapeutics: Implications for Future Market Competition 53

8 Gastrointestinal Stromal Tumor (GIST) Therapeutics: Future Players 54

8.1 Introduction 54

8.2 Company Profiles 55

8.2.1 Pfizer Inc. 55

8.2.2 Novartis AG 61

8.2.3 AB Science 67

8.2.4 Bayer AG 67

8.2.5 Other Companies in the GIST Therapeutics Market 72

9 GIST Therapeutics: Licensing and Partnership Deals 74

10 GIST Therapeutics: Appendix 76

10.1 Market Definitions 76

10.2 Abbreviations 76

10.3 Research Methodology 77

10.3.1 Coverage 77

10.3.2 Secondary Research 77

10.3.3 Forecasting 78

10.3.4 Primary Research 80

10.3.5 Expert Panel Validation 80

10.4 Contact Us 80

10.5 Disclaimer 80

10.6 Bibliography 81

1.1 List of Tables

Table 1: Incidence of GIST in Seven Major Markets#, 2010 6

Table 2: Occurrence Rate of Symptoms for GIST, 2010 7

Table 3: TNM Staging, GIST, 2010 8

Table 4: GIST Therapeutics Market, Global, Revenue ($m), 2005–2010 12

Table 5: GIST Therapeutics Market, Global, Forecast ($m), 2010–2017 13

Table 6: GIST Therapeutics Market, The US, Revenue ($m), 2005–2010 14

Table 7: GIST Therapeutics Market, The US, Forecast ($m), 2010–2017 15

Table 8: GIST Therapeutics Market, France, Revenue ($m), 2005–2010 16

Table 9: GIST Therapeutics Market, France, Forecast ($m), 2010–2017 17

Table 10: GIST Therapeutics Market, Germany, Revenue ($m), 2005–2010 18

Table 11: GIST Therapeutics Market, Germany, Forecast ($m), 2010–2017 19

Table 12: GIST Therapeutics Market, Italy, Revenue ($m), 2005–2010 20

Table 13: GIST Therapeutics Market, Italy, Forecast ($m), 2010–2017 21

Table 14: GIST Therapeutics Market, Spain, Revenue ($m), 2005–2010 22

Table 15: GIST Therapeutics Market, Spain, Forecast ($m), 2010–2017 23

Table 16: GIST Therapeutics Market, the UK, Revenue ($m), 2005–2010 24

Table 17: GIST Therapeutics Market, the UK, Forecast ($m), 2010–2017 25

Table 18: GIST Therapeutics Market, Japan, Revenue ($m), 2005–2010 26

Table 19: GIST Therapeutics Market, Japan, Forecast ($m), 2010–2017 27

Table 20: Sutent – GIST Efficacy Results 36

Table 21: GIST Therapeutics – Phase III Pipeline, 2011 37

Table 22: GIST Therapeutics – Phase II Pipeline, 2011 38

Table 23: GIST Therapeutics – Phase I Pipeline, 2011 38

Table 24: GIST Therapeutics – Preclinical Pipeline, 2011 38

Table 25: Nexavar Phase II Trial – Summary of Results, 2011 44

Table 26: GIST Therapeutics – Clinical Trials by Country, 2011 46

Table 27: GIST Therapeutics - Clinical Trials by Phase, 2011 47

Table 28: GIST Therapeutics - Clinical Trials by Status, 2011 48

Table 29: GIST Therapeutics - Prominent Sponsors, 2011 50

Table 30: GIST Therapeutics - Top Companies Participating in Therapeutics Clinical Trials, 2011 51

Table 31: Pfizer Inc. – Oncology, Pipeline, 2010 57

Table 32: Pfizer Deals, 2009-2010 58

Table 33: Novartis – Oncology Pipeline, 2010 63

Table 34: Novartis Deals, 2009-2010 64

Table 35: AB Science – Oncology Pipeline, 2010 67

Table 36: AB Science Deals, 2010 67

Table 37: Bayer AG – Oncology Pipeline, 2010 69

Table 38: Bayer AG Deals, 2009-2010 70

Table 39: GIST Therapeutics Market – Future Players 72

Table 40: GIST Therapeutics, Global, Deals 74

1.2 List of Figures

Figure 1: GIST Therapeutics Market, Global, Revenue ($m), 2005–2010 12

Figure 2: GIST Therapeutics Market, Global, Forecast ($m), 2010–2017 13

Figure 3: GIST Therapeutics Market, The US, Revenue ($m), 2005–2010 14

Figure 4: GIST Therapeutics Market, The US, Forecast ($m), 2010–2017 15

Figure 5: GIST Therapeutics Market, France, Revenue ($m), 2005–2010 16

Figure 6: GIST Therapeutics Market, France, Forecast ($m), 2010–2017 17

Figure 7: GIST Therapeutics Market, Germany, Revenue ($m), 2005–2010 18

Figure 8: GIST Therapeutics Market, Germany, Forecast ($m), 2010–2017 19

Figure 9: GIST Therapeutics Market, Italy, Revenue ($m), 2005–2010 20

Figure 10: GIST Therapeutics Market, Italy, Forecast ($m), 2010–2017 21

Figure 11: GIST Therapeutics Market, Spain, Revenue ($m), 2005–2010 22

Figure 12: GIST Therapeutics Market, Spain, Forecast ($m), 2010–2017 23

Figure 13: GIST Therapeutics Market, the UK, Revenue ($m), 2005–2010 24

Figure 14: GIST Therapeutics Market, the UK, Forecast ($m), 2010–2017 25

Figure 15: GIST Therapeutics Market, Japan, Revenue ($m), 2005–2010 26

Figure 16: GIST Therapeutics Market, Japan, Forecast ($m), 2010–2017 27

Figure 17: Opportunity and Unmet Need in the GIST Therapeutics Market 29

Figure 18: GIST Therapeutics – Strategic Competitor Assessment, 2010 31

Figure 19: Gleevec Phase III Trial Results – Progression-Free Survival 33

Figure 20: Gleevec Phase III Trial Results – Overall Response Rate 34

Figure 21: Sutent – Time to Tumor Progression in GIST Patients 36

Figure 22: GIST Therapeutics – Pipeline by Phase of Development, 2010 37

Figure 23: GIST Therapeutics – Technology Trends Analytic Framework, 2011 39

Figure 24: GIST Therapeutics – Technology Trends Analytic Framework – Description, 2011 40

Figure 25: GIST Therapeutics – Pipeline by Mechanism of Action, 2011 41

Figure 26: GIST Therapeutics – Clinical Trials by Country, 2011 46

Figure 27: GIST Therapeutics – Clinical Trials by Phase, 2011 47

Figure 28: GIST Therapeutics - Clinical Trials by Status, 2011 48

Figure 29: GIST Therapeutics - Overall Sponsors, 2011 49

Figure 30: GIST Therapeutics - Prominent Sponsors, 2011 49

Figure 31: GIST Therapeutics - Top Companies Participating in Therapeutics Clinical Trials, 2011 51

Figure 32: GIST Therapeutics Market, Drivers and Restraints 2010 52

Figure 33: Implications for Future Market Competition in the GIST Therapeutics Market, 2010 53

Figure 34: GIST Therapeutics Market – Pipeline by Company, 2010 54

Figure 35: GlobalData Market Forecasting Model 79Pfizer Inc.

Novartis AG

AB Science

Bayer AG

To order this report:

: Gastrointestinal Stromal Tumors (GIST) Therapeutics - Pipeline Assessment and Market Forecasts to 2017

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Nicolas Bombourg

Reportlinker

Email: [email protected]

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Intl: +1 805-652-2626

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