BURLINGTON, Mass., Dec. 6, 2010 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that the continued uptake of Celgene's Revlimid in the first-line setting and the launch of several premium-priced emerging therapies will drive robust 7.2 percent annual growth through 2019 in the multiple myeloma drug market.
The Pharmacor 2010 findings from the topic entitled Multiple Myeloma which will publish later this month reveal that although the first-line setting is currently dominated by Takeda/Janssen-Cilag/Janssen's Velcade in terms of patient and market share, sales of Velcade will be rapidly eclipsed by the dramatic growth of Revlimid. The findings also reveal that sales of Celgene's Thalidomide/Thalomid and Fujimoto Seiyaku's Thaled will be more aggressively eroded compared with Velcade, owing to the approval of Revlimid in the first-line setting.
Sales of both Revlimid and Velcade will also increase in the relapsed/refractory setting, despite the entrance of novel emerging therapies such as Celgene's pomalidomide and Onyx Pharmaceuticals/Ono Pharmaceutical's carfilzomib. Revlimid will be used in combination with carfilzomib, while Velcade will experience increased uptake in the relapsed/refractory setting in combination with other emerging agents such as Keryx Biopharmaceuticals/AEterna Zentaris's perifosine, Merck's Zolinza and Novartis's panobinostat.
"The most commercially promising emerging therapies in development -- pomalidomide and carfilzomib -- belong to the same drug classes as the highly successful currently available therapies, but these two agents will struggle to attain the same market share as well-established agents," said Decision Resources Analyst Andrew Merron, Ph.D. "Other promising emerging agents such as perifosine, Zolinza and panobinostat will introduce novel mechanisms of action into the myeloma treatment paradigm."
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SOURCE Decision Resources