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Seahorse Bioscience Announces Neuroscience 2012 Travel Award Winners

XF Technology Brings a New Perspective to Neuroscience Research


News provided by

Seahorse Bioscience

Oct 12, 2012, 09:39 ET

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BILLERICA, Mass., Oct. 12, 2012 /PRNewswire/ -- Seahorse Bioscience, the world leader in manufacturing instrumentation and assay kits for measuring cell metabolism, announces travel award recipients, who will be presenting data generated with the Seahorse XF Analyzer at the Neuroscience 2012 Conference, in New Orleans, Oct 13-17.

  • Shannon Rose Ph.D., postdoctoral fellow in Autism Research, at the Arkansas Children's Hospital Research Institute, in Little Rock, AR. Poster title: Increased Susceptibility to Reactive Oxygen Species in Autism Lymphoblastoid Cells is mediated by Mitochondrial Dysfunction.
  • Nathan Fried, Ph.D. candidate of Dr. Michael Oshinsky at the Jefferson Headache Centre, Department of Neurology, at Thomas Jefferson University, in Philadelphia, PA. Poster title: Mitochondrial Dysfunction in a Rat Model of Chronic Migraine.
  • Emily Cronin-Furman, Ph.D. candidate of Dr. Patricia A. Trimmer at the Virginia Commonwealth University, in Richmond, VA. Poster title: Decline in mitochondrial function after autophagic stress in a human Parkinson's disease cell model.

Seahorse XF Extracellular Flux Analyzers and stress test kits are the industry Gold Standard for simultaneously measuring the two major energy pathways of the cell - mitochondrial respiration and glycolysis - in a microplate, in real-time.  

"Our lab is using the Seahorse XF to help explore the specific mitochondrial electron transport chain deficiencies observed in a novel human Parkinson's Disease cell model. The opportunity to study mitochondrial bioenergetics in adherent cells is unique to the Seahorse XF technology," stated Dr. Patricia A. Trimmer, Ph.D., Associate Professor, Virginia Commonwealth University.  "With our cell model, we hope to use the Seahorse to develop therapies that can specifically improve mitochondrial function in Parkinson's Disease."

Seahorse supports the exploration of cell metabolism through travel awards that are offered to graduate students, post-doctoral researchers, and young investigators who present a talk or poster citing data generated on the XF platform at scientific meetings and conferences. Through this program, Seahorse seeks to increase the body of knowledge that is enabling new discoveries about the role of cell metabolism in pathophysiology.

"XF technology provides us with a means to investigate the functional significance of mitochondrial dysfunction in children with Autism Spectrum Disorders (ASD)," stated Shannon Rose Ph.D., postdoctoral fellow in Autism Research, at the Arkansas Children's Hospital Research Institute, in Little Rock, AR. "While poorly understood, mitochondrial dysfunction is one of the most common metabolic abnormalities affecting children with ASD. We believe mitochondrial dysfunction in children with ASD, and our findings, indicate that it may be associated with the cognitive and behavioral characteristics of the disorders. In addition, our studies on the XF have provided us with in vitro support for a clinical trial of N-acetyl-cysteine in children with ASD."

"These young researchers are to be congratulated. They are leading the way in neuroscience research, and by embracing XF technology are reaching new levels of discovery into cell metabolism and disease," stated Cynthia Egan, Director of Marketing at Seahorse Bioscience.

The XF Analyzer and stress test kits standardize the measurement of mitochondrial dysfunction detecting subtle changes in neuronal cell metabolism, before the development of observable neurodegeneration. This knowledge is enabling scientists to better understand the connection of physiological traits of cells with genomic and proteomic data, leading to a greater understanding, and new treatments of neurological disease.

About Seahorse Bioscience

Seahorse Bioscience XF Analyzers and stress test kits are the industry standard in cell metabolism measurements. Over 2,500 scientists worldwide are advancing their research in understanding the role of bioenergetics in Neurodegeneration, Aging, Cancer, Cardiovascular, Cell Physiology, Toxicology & Hepatobiology, Immunology, Infectious Diseases, Mitochondrial Diseases, Model Organisms, Obesity, Diabetes, Metabolic Disorders, Screening, and Translational Medicine. Founded in 2001, Seahorse Bioscience is headquartered in Billerica, Massachusetts, U.S., and has regional offices in Copenhagen, Denmark; and Shanghai, China.  Learn more about Seahorse Bioscience at www.seahorsebio.com.

About the Arkansas Children's Hospital Research Institute

Arkansas Children's Hospital Research Institute is the research home of UAMS and ACH physicians and scientists. Located in Little Rock on the ACH campus, ACHRI supports an interdisciplinary team with expertise and experience that span the breadth of medical disciplines. Learn more at achri.archildrens.org.

About Virginia Commonwealth University

Virginia Commonwealth University is a major, urban public research university with national and international rankings in sponsored research. Located in downtown Richmond, VCU enrolls more than 31,000 students in 222 degree and certificate programs in the arts, sciences and humanities. Sixty-six of the programs are unique in Virginia, many of them crossing the disciplines of VCU's 13 schools and one college. MCV Hospitals and the health sciences schools of Virginia Commonwealth University compose the VCU Medical Center, one of the nation's leading academic medical centers. Learn more at www.vcu.edu.

Press Contact:
Cynthia Egan
Director of Marketing
Seahorse Bioscience
[email protected]
978-671-1600

SOURCE Seahorse Bioscience

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