Subsalt Launches Secure Runtime for Broader Health Data Analysis Following Datavant Privacy Evaluation

New secure computing environment allows health systems to authorize analysis involving PHI without exposing patient-level data; Datavant evaluated Secure Runtime's privacy controls under HIPAA's Expert Determination standard.

CHARLOTTE, N.C., Sept. 14, 2026 /PRNewswire/ -- Subsalt today announced the general availability of Subsalt Secure Runtime, a secure computing environment that gives health systems a new way to make protected health information (PHI) available for analysis without exposing patient-level data.

Within Secure Runtime, anyone authorized by the health system can use Python to calculate metrics, test hypotheses, and visualize results through heatmaps, charts, and scatterplots. Organizations retain control over who can access the data, how it can be used, and which analytical outputs can be exported.

"Healthcare data is one of the most important assets for improving human health. But data-driven innovation can't come at the expense of patient privacy," said Ben Winokur, Chief Executive Officer of Subsalt. "The new secure computing environment in the Subsalt platform uniquely treats both data access and patient privacy as first-class concerns so that our customers can innovate quickly and responsibly."

Secure Runtime extends Subsalt's privacy-preserving health data platform, which generates de-identified digital twin patient populations from an institution's data. Datavant previously evaluated and certified Subsalt's digital twin technology under HIPAA's Expert Determination method.

In a new evaluation, Datavant extended its assessment to Secure Runtime, reviewing its aggregate outputs and the automated privacy tests that govern what can leave the environment. Datavant has now certified Subsalt's de-identification technology across both components of the platform.

"Subsalt demonstrated a clear commitment to data privacy through their active collaboration with our team, working closely with Datavant's privacy experts to integrate rigorous risk assessment metrics for attribute and membership disclosure risks and align with the 'very small' risk HIPAA Expert Determination standard," said Dr Emily Payne, Senior Data Scientist and Privacy Expert (Privacy Solutions) at Datavant.

Alongside Secure Runtime, Subsalt is making Subsalt MCP available to customers. Subsalt MCP enables AI chat tools to connect to an organization's custom de-identified datasets, subject to its existing access and governance controls.

"Historically, getting answers from health data has required clinical expertise to frame the question and technical expertise to navigate the underlying systems," said Luke Segars, Chief Technology Officer at Subsalt. "Natural-language interfaces help close that gap by allowing clinical experts to interact directly with the systems that hold the answers, including through agents acting on their behalf. Subsalt MCP makes that possible."

Subsalt Secure Runtime and Subsalt MCP are now generally available to new and existing Subsalt customers.

Subsalt will demonstrate both products at booth 5122 during Becker's Healthcare Health IT + Digital Health + RCM Meeting, taking place Sept. 14–17, 2026, in Chicago. Attendees can see how Claude uses Subsalt MCP to query de-identified health data.

To learn more, visit subsalt.ai.

About Subsalt

Subsalt is building the platform that unlocks faster health data access to advance healthcare innovation while keeping patient identities private. Its de-identification technology enables health systems and researchers to create high-quality de-identified digital twin data from clinical records for safer health AI, faster research, and modern education, while Subsalt Secure Runtime generates 100% accurate de-identified visuals while isolating end-users from PHI. Designed to meet HIPAA's Expert Determination standard and independently validated by Datavant, Subsalt enables healthcare to move from question to answer with greater speed and confidence. For more information, visit subsalt.ai.

About Datavant

Datavant is the data collaboration platform trusted for healthcare. With a mission to make the world's health data secure, accessible, and actionable, Datavant works with payers, providers, life sciences, legal and insurance clients globally to accelerate insights. Datavant enables more than 60 million healthcare records to move between thousands of organizations across the healthcare ecosystem, more than 80,000 hospitals and clinics, 75% of the 100 largest health systems, and 350+ real-world data partners. Datavant has office locations in Boston, Dallas, New York and San Diego, with international offices in Barcelona and Galway. To learn more about Datavant, visit www.datavant.com and follow us on LinkedIn. 

Media Contact
Hannah Drake
Head of Marketing
Subsalt
+1 (980) 449-2586
[email protected] 

SOURCE Subsalt