Why the Metabolic Plan Deanna Protocol® Is Helping ALS Patients

CORAL SPRINGS, Fla., June 22, 2016 /PRNewswire/ -- 2016 has seen a lot of new findings, discoveries, and some progress for ALS, but no viable cure has yet been discovered. Many people with ALS (PALS) are suffering from the disease.  The importance of extending life and easing symptoms until a cure is found is critical, and the Deanna Protocol is a Metabolic Plan that has been shown to help ALS patients with symptoms and quality of life.

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The HBO VICE episode "Die Trying" is particularly timely given the Right to Try bill recently introduced by Senator Ron Johnson (R-Wis.) - legislation that would give terminal patients the right to try experimental drugs that could potentially ease their symptoms or even save their lives.

Life expectancy after [an ALS] diagnosis typically ranges from two to five years, although the Cambridge, Massachusetts based non-profit biotech ALS Therapy Development Institute notes that at least one in 10 patients live more than 10 years following diagnosis.[1]

Why is the Deanna Protocol (DP) helping PALS? The metabolic plan focuses on cell metabolism. The plan works to produce additional energy to help keep the nerve cells alive in some ALS patients.

The DP™ Plan delivers Alpha-ketoglutarate (AKG) to the Krebs Cycle in the neurons. The increase in AKG enables their mitochondria to produce enough energy to keep cells alive, despite their exposure to an unhealthy amount of extracellular glutamate. [2]

Other nutrients in the DP help support the impact and deterioration caused by ALS. Understanding why these nutrients help is important.

GABA: PALS experience excitotoxicity. This causes uncontrollable muscle twitching and makes it nearly impossible for their muscles to function properly, even before those with ALS become paralyzed. GABA, an inhibitory neurotransmitter, is used to reduce excitotoxicity. This in turn reduces twitching and enables those with ALS to maintain control of the muscles and limbs.     

CoQ10, Niacin, and 5HTP: These are the precursors to NADH. NADH is one of the ingredients necessary for cells to produce the energy. Winning the Fight suggests that individuals with ALS take these three substances, which will allow their bodies to make NADH. (Taking NADH orally will not suffice because the body cannot absorb it orally, which is why we recommend taking the precursors.)

Everyone's body is different so the metabolic plan benefits vary with each individual. Reported responses by PALS taking the DP has been positive noting improvement. Winning the Fight plans to also begin researching the DP™ Plan and its effectiveness in conditions other than ALS.

Other neurodegenerative conditions (such as stroke, traumatic brain injury, concussion, Alzheimer's Disease, Parkinson's Disease, Multiple Sclerosis, and more) may have different causes, but they all share one common denominator: Glutamate. Regardless of the disease/condition, all nerve cells release excess glutamate into the extracellular space when they die and this glutamate will kill neighboring cells. Therefore, nerve cell death probably spreads throughout the nervous system the same way in all of these conditions. Since the DP™ Plan manages the spread of neuron death, it could likely help manage all neurodegenerative conditions, regardless of their initial cause. [3]

The DP is a natural metabolic solution that laboratory studies have proven effective in mice and anecdotal evidence has shown to be effective in humans. A 2014 study published on the NIH website concluded that "the metabolic therapy with Deanna Protocol supplementation delays disease progression and extends survival in amyotrophic lateral sclerosis (ALS) mouse model. Targeting energy metabolism with metabolic therapy produces a therapeutic effect in ALS mice which may prolong survival and quality of life in ALS patients." Until a cure or definitive treatment is discovered the right to try a natural metabolic therapy seems like a common sense approach to many PALS.[4]

About Simplesa®

Simplesa® was founded in 2013 because it saw a need and had a solution. ALS patients were having success following the Deanna Protocol, but it was too complex and expensive the way it was distributed. Simplesa® formulated products specifically for these ALS patients to simplify their regimen and lower the cost of the products they take. The brand is continuously on the lookout for other similar situations to help patients keep their supplemental and nutritional regimes simple.

Corporate Contact

Steve Margolis
[email protected]

References:

[1] https://alsnewstoday.com/2016/06/15/20160614die-trying-fridays-vice-on-hbo-episode-addresses-als

[2] http://www.winningthefight.org/why-the-deanna-protocolreg-plan-works.html

[3] http://www.winningthefight.org/why-the-deanna-protocolreg-plan-works.html

[4] http://www.ncbi.nlm.nih.gov/pubmed/25061944

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SOURCE Simplesa