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10.000 Proteindesigns, ein Nasslabor: Poreva Open startet erste Challenges

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News provided by

MegaRobo Technologies

Oct 19, 2026, 10:27 ET

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Fünf Herausforderungen im Proteindesign. Standardisierte Validierung im Nasslabor. Offenlegung experimenteller Daten. Die Anmeldung beginnt am 19. Oktober.

SUZHOU, China, 19. Oktober 2026 /PRNewswire/ -- Ein vielversprechendes Proteindesign ist nur der Anfang. Die eigentliche Bewährungsprobe findet im Labor statt.

MegaRobo Technologies, ein Technologieunternehmen, das eine „Intelligenz-Infrastruktur für die physische Welt" aufbaut, hat „Poreva Open" ins Leben gerufen – einen neuen globalen KI-Wettbewerb zum Proteindesign, bei dem Teams aus aller Welt aufgefordert sind, KI-generierte Entwürfe auf die Probe zu stellen. Mehr als 10.000 Entwürfe werden standardisierten Laborversuchen unterzogen, um einen gemeinsamen, experimentell fundierten Maßstab für KI-gesteuertes Proteindesign zu schaffen.

Das Ziel ist es, über Vorhersagen hinauszugehen und KI-entworfene Proteine näher an reale wissenschaftliche Anwendungen heranzuführen.

Poreva Open gab heute die ersten drei Herausforderungen bekannt; die Anmeldung beginnt am 19. Oktober. Der Wettbewerb wird unter anderem von Tencent Cloud, Twist Bioscience, Galatek, Vazyme, Guangzhou Pharmaceutical Digital Technology, Future Capital und dem Innoangel Fund unterstützt.

Ein experimenteller Standard, offen für alle Ansätze

Poreva Open steht nun Teams aus akademischen Einrichtungen, Forschungsorganisationen, Universitätslabors sowie Biotech- und KI-Unternehmen weltweit offen. Den Teilnehmern steht es frei, beliebige Modelle, Algorithmen oder Entwurfsmethoden zu verwenden.

Alle eingereichten Beiträge durchlaufen eine standardisierte, doppelblinde experimentelle Bewertung im Megalaxy Lab von MegaRobo. Ergebnisse und experimentelle Daten, einschließlich Daten zu erfolglosen Entwürfen, werden nach dem Wettbewerb unter Beachtung der Anforderungen hinsichtlich geistigen Eigentums und Compliance öffentlich zugänglich gemacht.

Fünf Herausforderungen, echte experimentelle Ergebnisse

Der erste Wettbewerb von Poreva Open umfasst fünf Herausforderungen, deren experimentelle Validierung eine Reihe von Messgrößen abdeckt, darunter Bindungsaffinität, thermische Stabilität, artübergreifende Reaktivität, pH-Selektivität, unspezifische Bindung und zelluläre Funktion.

Die ersten drei Herausforderungen konzentrieren sich auf EGFR, TNF-α und GLP-1R; zwei weitere Herausforderungen werden in der zweiten Runde bekannt gegeben. Ausgewählte Molekülkandidaten können in weitere Tests in biologischen Modellen, einschließlich Organoiden, übergehen.

Preise und wichtige Termine

Poreva Open stellt Preisgelder in Höhe von insgesamt 250.000 US-Dollar (1,7 Millionen RMB) bereit. Megalaxy Lab stellt den Teilnehmern zusätzlich Gutschriften für Laboruntersuchungen im Wert von 150.000 US-Dollar (1 Million RMB) kostenlos zur Verfügung. Die zehn besten Teilnehmer haben zudem die Chance, potenzielle Investitionen in Höhe von bis zu 1,5 Millionen US-Dollar zu erhalten.

  • 19. Okt. – 18. November: Anmeldung und Einreichungen für die Challenges 1-3
  • 9. November – 8. Dezember: Einreichungen für die Clannges 4-5
  • Bis März 2027: Experimentelle Validierung
  • April 2027: Ergebnisse und Veröffentlichung experimenteller Daten
  • April 2027: Team-Roadshow & Preisverleihung

Mehr erfahren und anmelden: https://porevaopen.megalaxylab.com/

Poreva Open — Beweise statt Versprechen.

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