Akadeum Life Sciences and BioIVT Collaborate to Provide Robust Starting Material to Developers of Cell Therapy Products

ANN ARBOR, Mich., Oct. 14, 2025 /PRNewswire/ -- Akadeum Life Sciences, the pioneer in gentle buoyant cell separation technology, and BioIVT, a leading global provider of high-quality biological specimens & research services, announce a collaboration aimed at providing healthier T cells via better qualified starting material, for developers and manufacturers of cell therapy products. As cell therapies are complex, the process is important to the success of the product - high-quality starting material is a critical first step in maximizing your results.

This collaboration underscores that reliable donor pools and upfront screening of leukopaks enable repeatable success downstream. When paired with BioIVT's LEUKOMAX™ leukopaks that are consistent in cellular makeup, the benefits of Akadeum's Human T Cell Leukopak Isolation Kit-GMP are increasingly more prominent: healthier, more viable T cells that directly address challenges faced for decades by cell therapy developers and manufacturers seeking more cost effective, repeatable and simple ways to increase cell health and subsequent effectiveness of therapeutics.

Improved Starting Material for Consistent Results, Simplified Workflows

BioIVT's LEUKOMAX™ leukopaks routinely contain fewer red blood cells (RBCs) compared to a competitor, critical for repeatability and consistency of data. When fewer RBCs are present, this lends itself to cells with better purity post-cell isolation, easier downstream processing, and reduced risk of red blood cell clumping. Akadeum has confirmed this performance advantage, with over 55 data points demonstrating very robust, consistent T cell isolation performance using their Human T Cell Leukopak Isolation Kit.

Akadeum also confirmed that BioIVT LEUKOMAX™ Leukopaks were 9 times more likely to keep red cell contamination under 40% than the other competitors leukopaks. This has enabled Akadeum to develop a workflow isolating T cells directly from leukopak material, without any cell washing instrumentation required. In-bag microbubble-based separation reduces handling time, minimizes risk of contamination, and scales quickly – enabling streamlined workflows, decentralized manufacturing opportunities, a reduction in risk and errors, and simplified training to ensure consistent performance at any scale.

"BioIVT is committed to providing our customers with the highest quality leukopaks in the industry. Our leukopak collection experts have decades of experience optimizing the LEUKOMAX™ leukopaks to meet and exceed our customers' expectations," stated Wini Luty, General Manager, Integrated CGT Operations. "We can work with our valued customers and trusted partners such as Akadeum to understand their needs, analyze collection data, and modify our protocols to provide the very best possible starting materials for research as well as therapies."

"Whether it's for research or therapeutic manufacturing, the material sourced and how it is handled at the beginning of the process is critical to success", said Brandon McNaughton, Akadeum's CEO. "Because of this we are pleased to be collaborating with a leading provider of high quality leukopaks that enable higher quality isolated cells"

Both companies are continuing to collaboratively generate additional workflow data to support a more gentle approach to cell therapy workflows - starting with better leukopaks and T cells.

An application note detailing the studies and results is forthcoming. For more information, visit www.akadeum.com and https://bioivt.com/

About Akadeum Life Sciences

Akadeum Life Sciences is dedicated to advancing cell separation technology through its unique buoyant microbubble platform, enabling researchers and manufacturers to achieve higher yields, better purity, and improved process simplicity across a range of life science applications. Our mission is to create separation technologies to advance human health. We envision a world where innovative separations empower researchers and clinicians to unlock breakthroughs in diagnostics, therapeutics, and basic research.

About BioIVT

BioIVT enables smarter science and accelerates medical breakthroughs by delivering high-quality personalized biospecimen solutions and research services to life science and diagnostic industries. Recognized as an industry leader, BioIVT specializes in control and disease state samples including human and animal tissues or preparations, ADME-Tox products and research services, cell and gene therapy products, blood, and other biofluids. By combining technical expertise and exceptional customer service with unmatched access to biological specimens, BioIVT serves the research community as a trusted partner in ELEVATING SCIENCE®.

Akadeum Media Contact: Brandon McNaughton, [email protected]

 BioIVT Media Contact: Charlie Chungu, Vice President of Marketing, [email protected] 

SOURCE Akadeum Life Sciences Inc