Avenda Health Expands Private Practice Network with the Deployment of Unfold AI at Arizona Urology, Bringing AI Prostate Cancer Mapping to the Southwest

Leading Phoenix urology practice adopts advanced AI cancer mapping to personalize surgical planning, enhance patient visualization, and pave the way for outpatient treatments

• Avenda Health deploys Unfold AI at Arizona Urology, bringing AI-powered 3D prostate cancer mapping to its three Phoenix-area locations.
• The implementation supports Unfold AI's expansion across U.S. private urology practices, bringing access to advanced prostate cancer treatment planning into community-based care settings.
• Arizona Urology plans to use Unfold AI to identify candidates for outpatient focal therapy, supporting minimally invasive treatment options for appropriate prostate cancer patients.

CULVER CITY, Calif., Sept. 17, 2026 /PRNewswire/ -- Avenda Health, an AI healthcare company creating the future of personalized prostate cancer care, today announced that Arizona Urology, a premier private urology practice with three locations across Phoenix, has adopted its Unfold AI platform. This first implementation in the state supports a key commercial expansion for Unfold AI in the Southwest U.S. and introduces advanced AI-driven prostate cancer mapping to support more precise treatment planning and patient counseling for localized prostate cancer.

One in eight men are diagnosed with prostate cancer in their lifetime. Today, clinicians predominantly rely on standard imaging and biopsy methods that can miss or underestimate clinically significant disease, creating ongoing challenges in determining the correct course of treatment. This diagnostic gap is particularly critical for the state's growing elderly population and patients referred from rural Arizona communities, who rely on regional care networks to access specialized treatment in the Phoenix metro area.

Unfold AI is an FDA-cleared, multimodal AI platform that combines patient-specific data to create a personalized 3D cancer map, revealing the true size and extent of disease and helping to uncover hidden cancer. By delivering a more complete and accurate view of the tumor and disease spread, Unfold AI empowers physicians to make better informed, patient-specific treatment decisions and reduces the risk of over- or under-treatment.

Unfold AI's clinical versatility makes it a robust tool to support patients and physicians throughout the entire prostate cancer care journey. Its interactive 3D maps serve as a powerful visual guide for patient counseling and decision support, helping patients and clinicians confidently select their treatment path. In the operating room, Unfold AI's spatial mapping actively guides procedures such as robotic prostatectomies, providing surgeons with more precise visualization of tumor boundaries. This level of precision assists clinicians in making critical margin decisions that allow them to better preserve the patient's erectile and urinary function while ensuring no disease is left behind, ultimately improving surgical success and protecting patient quality of life.  

"AI is incredibly powerful in modern medicine, and it is changing how we approach disease staging and treatment planning," said Pankaj Jain, MD, MBA, of Arizona Urology. "Bringing Unfold AI's clinical capabilities to our practice allows us to visually educate patients about the nature of their cancer, taking away the abstraction. We believe it will significantly improve our confidence in making surgical decisions and also establish the foundation needed to accurately guide treatment options across the care spectrum." 

Extensive, peer-reviewed research has demonstrated Unfold AI dramatically improves physician identification of tumor extent, increasing sensitivity from 37% to 97%, and helps physicians predict the cancer's spread into nearby anatomy with 92% accuracy, compared to 52% using MRI alone. For Arizona Urology, where prostate cancer cases make up to 40% of its high-volume clinical practice, Unfold AI serves as a vital precursor to identifying ideal candidates for successful, outpatient ablative procedures. The practice will primarily utilize the platform's 3D mapping for robotic radical prostatectomy planning and intrasurgical guidance, providing the advanced precision needed to guide margin decisions in real-time.

"We're thrilled to partner with Dr. Jain and the team at Arizona Urology as we expand Unfold AI's clinical footprint into the Southwest," said Shyam Natarajan, PhD, co-founder and CEO of Avenda Health. "By putting 3D precision mapping directly into the hands of community urologists, we are fulfilling our mission to democratize advanced cancer care and ensure that patient quality of life remains a top priority."

To support rapid clinical adoption, Unfold AI is backed by established billing pathways. It is the first urology AI tool to receive a Category III CPT code from the American Medical Association and a national Medicare payment rate for its use in outpatient hospital settings. The platform is now reimbursable by Medicare in physician office settings across the West Coast and Mountain West regions, giving private practices in Arizona and surrounding areas a direct pathway to offer this advanced care.

For more information on Avenda Health or to find a provider who offers Unfold AI, visit: avendahealth.com 

About Avenda Health
Avenda Health is creating a more personalized future of prostate cancer care. Using deep learning, Avenda Health software maps a patient's cancer in 3D, giving physicians precise information and the confidence to make care decisions. Dedicated to bringing this cutting-edge technology to all practices and physicians treating prostate cancer patients, Avenda Health aims to improve outcomes, preserve quality of life, and create a new standard of cancer care. To learn more, visit: avendahealth.com

About Arizona Urology
Arizona Urology is a premier medical clinic that provides the Valley with first-rate, patient-centered, and comprehensive urological health care. The practice has three clinics, conveniently located in Goodyear, Glendale, and Gilbert, Arizona. The board-certified physicians and medical staff provide high-quality and attentive care across the fields of urinary incontinence, robotics, laparoscopy, and treatments for urologic cancers of the bladder, prostate, testicle, and kidney. More information is available at https://www.arizona-urology.com.

SOURCE Avenda Health