Choose Health Launches Most Comprehensive At-Home Liver Function Test with 20+ Biomarkers and Clinical Risk Scores

New Test Brings Fatty Liver Risk Screening Home as Roughly 100 million Americans Live with Liver Disease, Most Undiagnosed

AUSTIN, Texas, Aug. 28, 2026 /PRNewswire/ -- Choose Health, an at-home blood testing company, announced the launch of the Comprehensive Liver Function Test, a self-collection blood test measuring 20+ liver health markers for a disease that affects roughly one third of U.S. adults but remains undiagnosed in the majority of cases.

"Fatty liver disease is arguably the most underdiagnosed condition in America," said Mark Holland, Founder of Choose Health. "The tragedy is that it's largely preventable and often reversible when identified early, but without universal screening, cases slip through until the damage is done. We built this test to change that."

A Silent Epidemic

Metabolic dysfunction-associated steatotic liver disease (MASLD) affects an estimated 38% of adults globally, projected to exceed 55% by 2040. In the U.S., roughly one third of adults may be affected, with only a fraction diagnosed.

Its trajectory can often be changed: AASLD guidance indicates 3 to 5% weight loss can improve steatosis, with above 10% needed to improve steatohepatitis and fibrosis.
 

What does the Choose Health Comprehensive Liver Function Test measure?

The test measures AST, ALT, GGT, total bilirubin and albumin; fasting glucose, HbA1c, fasting insulin and HOMA-IR; LDL, HDL, triglycerides, VLDL, ApoA1 and ApoB; and iron, UIBC, ferritin and transferrin saturation, alongside calculated scores: Fatty Liver Index, Hepatic Steatosis Index and AST:ALT ratio.

"These calculated scores are what actually matter clinically," said Dr. Alan Farrell, MB BCh BAO MSc, Chief Medical Officer at Choose Health and preventative medicine expert. "One elevated ALT reading doesn't say much. But when you combine multiple biomarkers into published indices like the Fatty Liver Index, patterns of steatosis and metabolic risk become much clearer."

Why does a liver test include metabolic and lipid markers?

Liver enzymes alone give an incomplete picture. Glucose, HbA1c, insulin and HOMA-IR add context on insulin resistance, commonly associated with MASLD. Lipid markers characterize cardiometabolic risk, and iron markers can surface results warranting clinical follow-up. FLI and HSI combine these with personal characteristics to estimate the likelihood of hepatic steatosis.

"We've been focused on liver health since 2018 because we saw this epidemic coming," said Holland. "With the rise of GLP-1 medications and awareness of metabolic health, now is the moment for consumers to take liver health as seriously as cholesterol or blood sugar."

Availability

The Comprehensive Liver Function Test is available across 48 states (excluding New York and Rhode Island). The test uses a finger-prick sample collected at home and returns physician-reviewed results in days.

About Choose Health

Choose Health is an Austin, Texas-based health technology company specializing in at-home blood testing for liver and metabolic health, founded in 2018. Choose Health has conducted over 200,000 tests processed through CAP-accredited and CLIA-certified laboratories, with results reviewed by licensed physicians.

Media Contact: Claire Gallaudet, 206-459-0665, [email protected]

The indices and calculations in this release are not intended to diagnose. Individuals with elevated or unexpected results should consult a healthcare professional.

SOURCE Choose Health