Emerging Research Suggests Mango Consumption Holds Potential to Positively Impact Blood Sugar in Obese Individuals and Mango Polyphenols May Contribute to Anti-Inflammatory Activity in Cells

BOSTON, April 23, 2013 /PRNewswire/ -- Two of the most serious health conditions facing Americans today—obesity and cancer—are the subject of new mango nutrition research presented this week at the Federation of American Societies for Experimental Biology (FASEB) in Boston. This preliminary research identifies important findings that merit further investigation to determine whether mangos can potentially have a positive effect on blood sugar in obese individuals and help to limit inflammation.

Preliminary research examines effects on blood sugar
A study led by Edralin Lucas, Ph.D., associate professor of nutritional sciences at Oklahoma State University, examined the effects of daily mango consumption on clinical parameters and body composition in obese subjects (body mass index, BMI ≥ 30kg/m²). Twenty adults (11 males and 9 females) participated in the study, which included daily dietary supplementation with 10 grams of freeze dried mango (equivalent to approximately 100 grams of fresh mango, according to Dr. Lucas) for 12 weeks.  

Blood sugar levels at the conclusion of the study were significantly lower than the baseline in both male and female subjects. There were no significant changes in body composition for either gender, and BMI increased significantly in female subjects but not male subjects compared to baseline. These findings are the result of a single study and more research is needed on the effects of mango consumption on human health. 

"The results of this study support what we learned in our recent animal model[1],[2], which found that mango improved blood glucose in mice fed a high fat diet," said Dr. Lucas. "Although the mechanism by which mango exerts its effects warrants further investigation, we do know that mangos contain a complex mixture of polyphenolic compounds. Research has shown that several other plants and their polyphenolic compounds, such as isoflavone from soy[3], epigallocatechin gallate from green tea[4], and proanthocyanidin from grape seed[5], have a positive effect on adipose tissue."

Exploring anti-inflammatory properties of mango polyphenols
Research led by Susanne Mertens-Talcott, Ph.D., Assistant Professor and Director for Research, Institute for Obesity Research and Program Evaluation of Texas A&M University, examined the effects of polyphenols found in fresh mangos on cancerous and non-cancerous breast cells. This study suggests that mango polyphenols may limit inflammatory response in both cancerous and non-cancerous breast cells. Because this was an in vitro study, more research is needed to determine whether mango polyphenols can have the same effect in humans.

Mangos deliver antioxidants, vitamins, and minerals
A nutrient rich fruit, mangos contain over 20 different vitamins and minerals, supporting optimal function of processes throughout the body. Mangos are an excellent source of the antioxidant vitamins C and A. Vitamin C is important for wound healing and immune function; and vitamin A is critical for vision and helps maintain healthy skin. In addition, mangos are rich in folate, which helps the body make blood cells and DNA. Mangos also provide fiber, which slows the absorption of sugar in the blood stream and may help support weight management by increasing feelings of fullness.

For more information on mango nutrition research, visit www.mango.org.

About The National Mango Board
The National Mango Board is a national promotion and research organization, which is supported by assessments from both domestic and imported mangos. The board was designed to drive awareness and consumption of fresh mangos in the U.S. One cup of mango is only 100 calories, an excellent source of vitamins A and C, a good source of fiber and an amazing source of tropical flavor.

Mango availability per capita has increased 32 percent since 2005 to an estimated 2.47 pounds per year in 2012. Mango import volume for 2012 was 804 million pounds. Learn more at www.mango.org.

[1] Lucas A, Li W, Brown A, Li W, Peterson SK, Wang Y, Perkins-Veazie P, Clarke SL, Smith BJ. Mango Modulates Blood Glucose Similar to Rosiglitazone without Compromising Bone Parameters in Mice Fed High Fat Diet.  J Pharm Nutr Sci. 2012; 2: 115-126.

[2] Lucas A, Li W, Peterson SK, Brown A, Kuvibidila S, Perkins-Veazie P, Clarke SI, Smith BJ. Mango modulates body fat and plasma glucose and lipids in mice fed a high-fat diet. Brit J Nutr. 2011; 106: 1495-1505.

[3] Kim HK, Nelson-Dooley C, Della-Fera MA, Yang JY, Zhang W, Duan J, Hartzell DL, Hamrick MW, Baile CA. Genistein decreases food intake, body weight, and fat pad weight and causes adipose tissue apoptosis in ovariectomized female mice. J Nutr. 2006 Feb;136(2):409-14.

[4] Hasegawa N, Yamda N, Mori M. Powdered green tea has antilipogenic effect on Zucker rats fed a high-fat diet. Phytother Res. 2003 May;17(5):477-80.

[5] Tsuda T, Horio F, Uchida K, Aoki H, Osawa T.   Dietary cyanidin 3-O-beta-D-glucoside-rich purple corn color prevents obesity and ameliorates hyperglycemia in mice. J Nutr. 2003 Jul;133(7):2125-30.

Contact:
Allison Beadle
512.963.6930
[email protected]

SOURCE The National Mango Board