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European Hematology Association: La exposición retrasada a las infecciones comunes causa leucemia aguda en la infancia
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European Hematology Association Logo (PRNewsfoto/European Hematology Association)

News provided by

European Hematology Association

Jun 23, 2017, 02:30 ET

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MADRID, June 23, 2017 /PRNewswire/ --

La leucemia aguda es el tipo de cáncer más común en la infancia, y su incidencia está aumentando, sobre todo en los países socio-económicamente avanzados. Las infecciones como desencadenante del desarrollo de la leucemia en niños se ha debatido con controversia desde hace décadas, y la ocurrencia de la leucemia en agrupaciones de espacio-tiempo es un apoyo frente a esta hipótesis. Pese a la evidencia experimental, se demuestra que la conexión de la exposición a la infección y a la leucemia infantil son poco habituales. Tanto nosotros como nuestros colegas hemos establecido y caracterizado dos modelos de ratones genéticamente modificados que representan los subtipos clásicos de leucemia infantil (Pax5+/- y TEL-AML1). El ratón desarrollo leucemia linfoblástica aguda solo después de su exposición a un entorno de infección común y representa un fenotipo similar en comparación con la leucemia linfoblástica aguda de los niños. Este trabajo ofrece por primera vez una nueva visión dentro del papel de la infección en el desarrollo de la leucemia, ofreciendo además nuevas aproximaciones hacia la prevención de la leucemia.

     (Logo: http://mma.prnewswire.com/media/524821/EHA_Logo.jpg )

Presentadora: Doctora Julia Hauer

Afiliación: Clinic for Pediatric Oncology, Haematology and Clinical Immunology, Düsseldorf, Alemania

Tema: EXPOSURE TO INFECTION TRIGGERS PAX5 AND ETV6-RUNX1 CHILDHOOD BCP-ALL

El abstracto S148 se presentará por medio de Julia Hauer el viernes 23 de junio de 15:45 a 17:00 en el hall A.

Acerca del Congreso Anual de la EHA
La hematología es una especialidad que cubre todo lo relacionado con la sangre: sus orígenes en la medula ósea, enfermedades de la sangre y sus tratamientos. Se van a presentar los últimos datos acerca de la investigación y desarrollos. Los temas abarcan desde la psicología de las células madre y su desarrollo hasta la leucemia, linfoma, mieloma - diagnosis y tratamiento; células de los glóbulos rojos, células de los glóbulos blancos y enfermedades de las plaquetas; trombosis y enfermedades hemorrágicas.

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