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European Wellness colabora con la Universidad de Heidelberg en la publicación en una revista
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Apr 28, 2023, 12:15 ET

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-  European Wellness colabora con la Universidad de Heidelberg en la publicación en una revista de "Antienvejecimiento sinérgico mediante la reprogramación específica de células senescentes"

HEIDELBERG, Alemania, 28 de abril de 2023 /PRNewswire/ -- European Wellness Academy (EWA), rama educativa de European Wellness Biomedical Group (Grupo EW), ha colaborado con la Universidad de Heidelberg en la publicación de una revista. El proyecto de investigación, titulado "antienvejecimiento sinérgico mediante la reprogramación específica de células senescentes", ha sido financiado por la EWA y publicado en una prestigiosa revista científica.

Este método es el preferido para la reprogramación parcial cuidadosamente regulada con el fin de reducir la probabilidad de cáncer y fallos orgánicos causados por la pérdida de identidad celular. El enfoque fue capaz de improvisar el fenotipo secretor asociado a la senescencia (SASP), que a su vez redujo el estado inflamatorio crónico relacionado con el envejecimiento y la senescencia secundaria en las células adyacente.

Esta investigación estudiará la posibilidad de que la intervención sobre la senescencia celular pueda mejorar el proceso de envejecimiento y la reparación de daños con el objetivo de prolongar la vida sana y reducir el riesgo de fragilidad. Se destacan las limitaciones y los retos que plantea el uso de estos avances para investigar hipótesis y orientaciones prospectivas para futuras investigaciones de importancia traslacional.

Los tratamientos de reprogramación en células senescentes tienen la capacidad de mantener componentes beneficiosos en comparación con la eliminación de células senescentes. El estudio también demostró que la senescencia potencia la reprogramación, sirviendo potencialmente como mecanismo de automodificación, permitiendo que el mismo nivel de expresión de los factores de reprogramación sea más eficaz en el entorno senescente. Cuando el entorno senescente se atenúa o invierte, la eficacia de la reprogramación disminuye, lo que evita los daños causados por la sobreinducción.

Cuando el rejuvenecimiento se hace más prominente, la reprogramación local pierde el estímulo del SASP y se integra con un mecanismo de inducción regulado para evitar tumores y la pérdida de funciones celulares. Este método debería ejecutarse en tejidos no mortales, como el adiposo, la fascia en contraposición al miocardio y los nervios.

La colaboración entre ambas instituciones representa un importante paso adelante en el campo de la investigación antienvejecimiento. Los resultados del estudio proporcionan una base sólida para la investigación y el desarrollo en este campo, con el potencial de transformar la forma de abordar el proceso de envejecimiento.

European Wellness Academy

Una academia sin ánimo de lucro del Grupo EW, ubicada en Alemania, Reino Unido, Suiza, Grecia y Malasia, como organismo autorizado de DPC con un ala de formación y desarrollo de primera calidad que resuelve en torno a modalidades de Medicina Bio-Regenerativa de vanguardia para profesionales e investigadores. Cuenta con muchos años de experiencia clínica combinada y un equipo académico central formado por médicos y científicos cualificados con numerosas afiliaciones y acreditaciones internacionales.

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