Hot Melt Extrusion: Accelerating Drug Development for Poorly Soluble APIs, Upcoming Webinar Hosted by Xtalks

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Aug 27, 2025, 08:30 ET

In this free webinar, gain an overview of common formulation challenges in global pharmaceutical development, particularly for APIs with poor solubility and varying physicochemical properties. Attendees will learn about hot melt extrusion (HME) as a leading technology for improving solubility and bioavailability. The featured speakers will share key considerations in pre-formulation, formulation development, process design and scale-up to commercial manufacturing. Attendees will gain practical guidance on how to design HME-based formulations and define critical process parameters to allow for rapid and right-first-time product development.

TORONTO, Aug. 27, 2025 /PRNewswire/ -- In today's pharmaceutical landscape, over 80% of R&D candidates in the global pipeline suffer from poor solubility, creating a significant challenge for effective drug delivery. To ensure that innovative medicines reach patients worldwide, advanced formulation and process technologies are necessary to overcome bioavailability issues, such as lipid-based systems and amorphous solid dispersions.

https://extruders.leistritz.com/en/start

This webinar offers a special focus on hot melt extrusion (HME), providing a comprehensive guide to formulation and process development, equipment design and scale-up. Attendees will benefit from insights into how to make informed decisions when analyzing and choosing technology options for their processes.

The session provides practical instruction on setting up HME processes. Based on a case study, this webinar will also provide evidence regarding strategies that can significantly accelerate formulation and overall product development.

Register for this webinar to benefit from the combined perspectives from market leaders in the CDMO area and extrusion technologies, offering a holistic view on HME implementation from formulation to equipment design.

Join Dr. Klaus Pollinger, Group Director Global Product Development, Aenova Group; Dr. George Shlieout, Head of MS&T, Aenova Group; and Kathrin Reusch, Product Manager Pharma & Life Science, Leistritz Extrusionstechnik GmbH, for the live webinar on Wednesday, September 17, 2025, at 9am EDT (3pm CEST/EU-Central).

For more information, or to register for this event, visit Hot Melt Extrusion: Accelerating Drug Development for Poorly Soluble APIs.

ABOUT XTALKS

Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars and digital content to the global life science, food, healthcare and medical device communities. Every year, thousands of industry practitioners (from pharmaceutical, biotechnology, food, healthcare and medical device companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps professionals stay current with industry developments, regulations and jobs. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

To learn more about Xtalks, visit www.xtalks.com
For information about hosting a webinar, visit www.xtalks.com/why-host-a-webinar/

Contact:
Vera Kovacevic
Tel: +1 (416) 977-6555 x371
Email: [email protected]

SOURCE Xtalks