INSTYTUTUM Clinical Study Shows a Three-Year Reduction in Calculated Skin Biological Age in 84 Days
Swiss longevity skincare brand reveals new clinical data supporting a new approach to skin health, biological aging and skinspan
NEW YORK, Sept. 28, 2026 /PRNewswire/ -- INSTYTUTUM, the Swiss longevity skincare brand founded by longevity scientist and biotech innovator Dr. Natalia Bobok, PhD, today announced results from a new independent clinical-instrumental study demonstrating a three-year reduction in calculated skin biological age after 84 days of use of the complete INSTYTUTUM skincare routine.*
The findings reinforce INSTYTUTUM's longevity-first approach to skincare: moving beyond visible signs of aging to address the biological processes that shape how skin changes over time. Combining biotechnology and clinical research, INSTYTUTUM focuses not simply on better-looking skin today, but on a longer skinspan, more years of healthy, resilient, high-functioning skin.
THE RESULTS: 3-YEAR REDUCTION IN CALCULATED SKIN BIOLOGICAL AGE IN 84 DAYS
Conducted by an independent European clinical testing center, the 84-day open-label study evaluated 21 women ages 35–60 with visible signs of chrono and/or photo-aging. Participants used the complete seven-product INSTYTUTUM morning and evening routine, with assessments conducted at baseline and Days 28, 56 and 84.
By Day 84, the study showed:
- -3.0 years — average reduction in calculated skin biological age
- +16.2% — improvement in skin firmness
- 100% — reported improved skin hydration, smoother texture, and increased radiance
Calculated skin biological age continued to decrease throughout the study, from 49.7 years at baseline to 46.6 years at Day 84. Unlike chronological age, skin biological age reflects measurable changes in the skin over time.
INSTYTUTUM turns longevity science into high-performance skincare. High concentrations of next-generation active ingredients are engineered to work in synergy, while advanced delivery technologies optimize their performance, bringing professional-level efficacy home with immediate impact and long-lasting results. The complete INSTYTUTUM routine is clinically tested to reduce calculated skin biological age, setting a new benchmark for what high-performance skincare can achieve.
About INSTYTUTUM
INSTYTUTUM is the Swiss longevity brand designed to manage biological age. Founded by Dr. Natalia Bobok, PhD — Longevity Scientist, Biotech Innovator & Serial Beauty Entrepreneur. INSTYTUTUM is named by Forbes USA as the next industry disruptor. Dr. Natalia Bobok was recognized by Entrepreneur Middle East as "one of the most influential voices shaping the future of beauty, and a defining longevity scientist of her generation." In 2026, INSTYTUTUM was named a finalist in the Best Breakthrough Beauty Brand category of the 2026 BeautyMatter Awards, recognizing standout achievement and the people, brands, and businesses pushing the beauty industry forward. INSTYTUTUM is trusted by Oscar nominees, Grammy performers, leading doctors, and 200,000+ clients worldwide.
For those who invest in their healthspan — not just their lifespan.
High Res Imagery: HERE
**Based on an 84-day open-label clinical study of the full 7-product INSTYTUTUM AM/PM routine among 21 women aged 35–60. The claimed reduction in calculated skin biological age is an average age equivalent based solely on periocular (crow's feet) wrinkle depth measurement and does not constitute a medical or comprehensive assessment of biological age. Individual results may vary. Full disclaimer: https://us.instytutum.com/en/biological-age-research/
SOURCE INSTYTUTUM
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