MOBILion Systems to Highlight Customer Use Cases from its MOBIE® Platform and Unveil Plans for their Next Generation Proteomics Platform at ASMS 2025

CHADDS FORD, Pa., May 27, 2025 /PRNewswire/ -- MOBILion Systems, Inc., a leader in separation science innovation, will attend and exhibit at the 73rd Annual American Society for Mass Spectrometry (ASMS) Conference in Baltimore, MD from June 1–5. The company will highlight the transformative impact its MOBIE^® High-Resolution Ion Mobility product is having across a wide range of applications and showcase early performance of its next-generation proteomics system, BILLIE™.

More than 50 abstracts including oral and poster presentations will demonstrate how independent researchers across pharmaceutical development, chiral molecule analysis, lipidomics and PFAS research are driving innovation with the MOBIE system. These real-world applications reflect growing market adoption and the expanding impact of MOBILion's existing MOBIE product across critical and emerging workflows. Alongside its commercial platform, MOBILion will present the latest data and collaborator results powered by its most recent advancement: Parallel Accumulation Mobility Aligned Fragmentation (PAMAF). This novel mode of operation is the foundation for the forthcoming BILLIE platform, enabling increased speed, sensitivity, and selectivity for LC-HRMS-based proteomics.

"ASMS is the ideal venue to highlight the exciting breakthroughs our users are achieving with the MOBIE system, and to share where we are heading with BILLIE," said Melissa Sherman, Ph.D., CEO of MOBILion Systems. "Our team has been on a journey to improve separation science, holistically. There is nothing more rewarding than seeing our users show to industry peers the characterization boundaries being broken with the MOBIE product. This year is particularly exciting for the MOBILion team because we are also providing a first look of our next product in development. The performance improvements BILLIE will offer through PAMAF represent a true step-change in mass spectrometry workflows allowing researchers to push the boundaries of what's possible in proteomics and beyond."

PAMAF is designed to address the long-standing limitations of traditional tandem quadrupole mass spectrometry by replacing the slow and lossy quadrupole isolation step with high-resolution ion mobility separation. This allows BILLIE to deliver MS/MS fragmentation at over 500 Hz and utilize nearly 100% of available ions, resulting in faster data acquisition, greater signal sensitivity, and improved quantitative accuracy in even the most challenging biological samples.

Daniel DeBord, Ph.D., Chief Technology Officer at MOBILion, added, "For over two decades, scientists have worked to overcome the speed and sensitivity limitations of traditional MS workflows. PAMAF enables fragmentation data with dramatically higher signal-to-noise at speeds up to five times faster than conventional systems. We're excited to showcase this next frontier in proteomics at ASMS."

What to Expect from MOBILion at ASMS 2025

Breakfast Seminars (June 2–4, 7:00–8:15 a.m., Room 321, Baltimore Convention Center)

Monday, June 2:

• Dr. Sarah Choyke (Eurofins Specialty Services)
  How MOBIE enhances forensic PFAS analysis by improving separation, reducing ambiguity, and accelerating workflows for faster, more confident results.
• Dr. Andrew Feilden (Bicycle Therapeutics)
  Exploring analytical challenges of Bicycle peptides, focusing on structural characterization and impurity identification in clinical development.

Tuesday, June 3:

• Prof. Birgit Schilling & Dr. Joanna Bons (Buck Institute for Research on Aging)
  Using PAMAF to reveal significant succinylation and proteome changes in acute kidney injury, identifying potential targets for intervention and protection.
• Dr. Ben Orsburn (University of Pittsburgh School of Medicine)
  How PAMAF enables near 100% ion utilization to improve sensitivity and efficiency in single-cell proteomics.

Wednesday, June 4:

• Dr. John R. Yates (The Scripps Research Institute)
  How PAMAF accelerates and enhances the DeGlyPHER workflow for precise N-glycosylation analysis, improving speed, sensitivity, and insights in SARS-CoV-2 and other vaccine development.
• Dr. Daniel DeBord (MOBILion Systems)
  A look at how PAMAF boosts speed, sensitivity, and depth in proteomic analysis through enhanced LC-MS performance.

Space is limited — register here to reserve your spot.

Full ASMS Schedule – Posters & Presentations:

Explore all scientific sessions, posters, and talks featuring MOBILion's technologies and collaborations.

Exhibition Booth #434

Meet the team and learn how MOBILion is transforming LC-MS workflows through HRIM-powered platforms.

Hospitality Suite Afterparty

Join us on the evening of Monday, June 2, from 8:00–11:00 PM in the Poe Room at the Hilton Baltimore for an exclusive ASMS afterparty. Enjoy mocktails, temporary tattoos, and a silent disco —connect with peers and celebrate innovation in a fun, relaxed setting.

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About MOBILion Systems Inc.
MOBILion Systems is Revealing What Others Leave Unseen®, transforming next-generation separation science with its proprietary SLIM (Structures for Lossless Ion Manipulation) technology. When integrated with mass spectrometry, SLIM enables high-resolution, rapid, and reproducible analyses—empowering researchers to more deeply, accurately, and efficiently characterize complex samples. This innovation is accelerating breakthroughs in proteomics, drug development and characterization, biomarker discovery, diagnostics, food safety, and environmental testing. Headquartered in Chadds Ford, Pennsylvania, MOBILion is advancing molecular characterization in the heart of Philadelphia's biopharmaceutical and medical innovation corridor. Learn more at mobilionsystems.com or connect with us on LinkedIn.

Media contact:
Hannah Steele
The Scott Partnership
[email protected]
+44 1477 539 539

SOURCE MOBILion Systems