Unlike existing cold and flu medicines that leave consumers managing symptoms every 4-6 hours, Mucinex® 12HR Cold & Fever Multi-Symptom is a first-of-its-kind OTC medication designed to address the #1 unmet need in the cold and flu category—long-lasting symptom relief*—delivering 12 hours of relief in just one dose. With three times longer relief**, fans can stay focused on gameday from kickoff to the final whistle. It's a new 12-hour relief powerhouse designed for fans who refuse to miss a single moment.
"Cold and flu symptoms don't stick to a schedule, yet many medicines only provide four hours of relief — meaning symptoms can return, making it harder to show up for the moments that matter" said Henry Turgoose, Vice President of Marketing for Upper Respiratory at Reckitt. "For years, consumers have wanted longer-lasting symptom relief that helps them stay focused on their day, not their symptoms. With Mucinex® 12HR Cold & Fever Multi-Symptom, they can spend less time feeling their symptoms and more time staying fully engaged, from Football Sunday to everyday life."
To bring the product's all-day relief benefit to life, Mucinex® is launching "Go All 12," a new campaign inspired by one of the ultimate all-day occasions: Football Sunday. As part of the campaign, Mucinex® is teaming up with reality TV star, content creator, and entrepreneur JoJo Fletcher to show fans how they can Go All 12 without letting cold and flu symptoms interrupt their gameday traditions. As a busy working mom, wife of a former NFL player and devoted football fan, JoJo knows firsthand that cold and flu symptoms do not take a timeout on gameday.
"Jordan may not be playing anymore, but football Sundays are still an all-day event in our house," JoJo shared. "Between being a busy working mom, along with balancing Jordan's broadcasting schedule, gameday is one of those traditions we really look forward to as a family and I don't want cold and flu symptoms getting in the way. Mucinex® 12HR Cold & Fever Multi-Symptom gives me long-lasting relief so I can stay in the game all day long."
To bring the campaign into the action, JoJo Fletcher and Mucinex® hosted the Go All 12 Tailgate Experience in Tampa Bay on September 27. The activation brought football fans, media and influencers together for an immersive experience featuring branded giveaways, interactive games and exclusive VIP access.
The notorious Mr. Mucus crashed the tailgate, ready to buddy up with JoJo and Tampa fans, but to his surprise and thanks to new Mucinex® 12HR Cold & Fever Multi-Symptom, Mr. Mucus was sidelined from the fun. JoJo is now amplifying this run-in across her social channels throughout cold and flu season, showing fans how long-lasting symptom relief helps her stay in the game all day long.
In addition to the tailgate, the brand will partner with ESPN and Disney CreativeWorks on custom content featuring ESPN analyst Anthony "Booger" McFarland, integrating Mr. Mucus into football-centric storytelling across paid and owned channels. The campaign will also extend to DoorDash®, positioning Mucinex® 12HR Cold & Fever Multi-Symptom as the All-Day MVP with a special Football Sunday promotion, amplified through JoJo Fletcher, a lifestyle content creator and a social-first delivery featuring Mr. Mucus.
The fully integrated campaign includes:
- Celebrity Partnership: Mucinex® partnered with reality TV star, content creator and entrepreneur JoJo Fletcher to bring "Go All 12" to life, sharing how she manages cold and flu symptoms while staying committed to her family's football traditions across earned, paid, and owned channels.
- Tailgate Experience Activation: Mucinex® welcomed 400+ football fans to an interactive Go All 12 Tailgate Experience in Tampa Bay (September 27, 2026) hosted by JoJo Fletcher, bringing together media, influencers, and consumers for hands-on brand engagement.
- Sports Media Integration: Mucinex® partnered with ESPN and Disney CreativeWorks on football-focused content featuring analyst Anthony "Booger" McFarland. As the presenting sponsor of NFL Primetime Presented by Mucinex, the brand is bringing its Go All 12 campaign to football fans across linear, streaming, digital, and social platforms.
- Delivery Integration: Mucinex® partnered with DoorDash® to make Mucinex® 12HR Cold & Fever Multi-Symptom available nationwide, with fans receiving $2 off delivery from 11/1–12/3, while supplies last.
- Brand Mascot Integration: Inspired by the rise of the Brand Mascot Era, Mucinex® is leveling up the role of Mr. Mucus this football season, bringing him into tailgates, stadiums, and living rooms—only to be sidelined for 12 hours when Mucinex® 12HR Cold & Fever Multi-Symptom enters the scene.
- Retail Partnerships: Mucinex® will bring the campaign to life through in-store omnichannel activations at major retailers, including Walmart, Walgreens, and CVS Pharmacy.
Mucinex® 12HR Cold & Fever Multi-Symptom launched in 2026 and is a first-of-its-kind OTC medication designed to address the #1 unmet need in the cold and flu category —long-lasting symptom relief*— delivering up to 12 hours of relief in just one dose, addressing consumers' desire for longer-lasting symptom relief without needing to continually manage symptoms throughout the day. For more information on Mucinex® 12HR Cold & Fever Multi-Symptom, visit www.Mucinex.com, Walmart, Walgreens, and CVS Pharmacy.
About Mucinex®
Mucinex® always has your back when cold and flu symptoms hit, offering a wide range of formulations that can help ease discomfort, day and night. Whether you're struggling with a nasty cough, unpleasant fever and sore throat or a nose that just won't stop running, the Mucinex® family of products provide relief you can trust when it's time to kick all your worst symptoms to the curb.
For more than 20 years, Mucinex® has provided consumers with world-class mucus and congestion relief, and it is #1 in more categories than you can imagine:
- The #1 most trusted brand among physicians for cough and cold symptoms***
- The #1 most trusted brand among respiratory specialists for cough and cold symptoms****
- The #1 most trusted brand among physicians for their own family's cough & cold symptoms*****
For more information, visit Mucinex.com
About Reckitt®
Reckitt is a world-class consumer health and hygiene company on a mission to deliver better health in more hands, every day. Founded in 1840 in the United Kingdom, Reckitt is home to some of the world's most trusted and recognised brands across Germ Protection, Household Care, Intimate Wellness and Self Care, including Dettol, Durex, Finish, Gaviscon, Harpic, Lysol, Mucinex, Nurofen, Strepsils, Vanish and Veet.
Operating in more than 80 countries, Reckitt sells approximately 30 million products every day and employs around 36,000 people worldwide. Through trusted brands, science-led innovation and deep consumer understanding, Reckitt helps make health, hygiene and wellbeing more accessible for millions of people while creating sustainable value for consumers, customers, communities and shareholders.
For more information, visit www.reckitt.com/us.
Reckitt is the trading name of the Reckitt group of companies
*Source: Clear C&F U&A 2022
**Compared to 1 dose of 4-hour medicine without re-dosing.
***IQVIA, ProVoice Survey, fielded to 3,930 physicians, September 1-December 31, 2024
****IQVIA, ProVoice Survey, fielded to 570 respiratory specialists, September 1-December 31, 2024
*****IQVIA, ProVoice Survey, fielded to 3,930 respiratory specialists, September 1-December 31, 2024
SOURCE Mucinex
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